Exam 14: Mendelian Genetics

Marfan syndrome in humans is caused by an abnormality of the connective tissue protein fibrillin. Patients are usually very tall and thin, with long spindly fingers, curvature of the spine, sometimes weakened arterial walls, and sometimes eye problems, such as lens dislocation. Which of the following would you conclude about Marfan syndrome from this information?

When Mendel set up a Parental (P) cross between true breeding purple and white flowered plants to generate the F1 and then allowed the F1 to self-pollinate to generate the F2 he saw a dominant to recessive ratio of 3:1. What phenotypic ratio would be expected if he crossed the F1 with the original purple parent?

In cattle, roan coat color (mixed red and white hairs) occurs in the heterozygous (CRCW) offspring of red (CRCR) and white (CWCW) homozygotes. Which of the following crosses would produce offspring in the ratio of 1 red:2 roan:1 white?

Hutchinson-Gilford progeria is an exceedingly rare human genetic disorder in which individuals look very old even as young children, experience very early senility and severe coronary artery disease, and have a life expectancy of 13 years. Which of the following statements represents the most likely assumption regarding this disorder?

Which of the following relationships among alleles of a single gene best explains the observation that a single change in the gene encoding α-keratin results in chickens with frizzled feathers, increased food consumption, higher heart rate and delayed sexual maturity?

Assuming independent assortment at all loci, what is the probability that a cross between the following parents, AABbCc × AaBbCc, will produce an AaBbCc offspring?

Which of the following describes why Mendel continued some of his experiments into the F2 or F3 generation?

An obstetrician knows that her patient's fetus is at risk for a serious disorder that is detectable biochemically in fetal cells. The obstetrician would most reasonably offer which of the following procedures to her patient?

Which of the following statements best describes the addition rule of probability?

Albinism is a recessive trait where an individual does not produce the pigment melanin. A man and woman who both produce melanin have one child out of three who has albinism. What are the genotypes of the man and woman?

Gene S controls the sharpness of spines in a type of cactus. Cacti with the dominant allele, S, have sharp spines, whereas homozygous recessive ss cacti have dull spines. Also, a second gene, N, determines whether or not cacti have spines. Homozygous recessive nn cacti have no spines at all. The relationship between genes S and N is an example of which of the following inheritance patterns?

Gene S controls the sharpness of spines in a type of cactus. Cacti with the dominant allele, S, have sharp spines, whereas homozygous recessive ss cacti have dull spines. A second gene, N, determines whether or not cactuses have spines. Homozygous recessive nn cactuses have no spines at all. Which of the following explain why a crossing a true breeding spineless cactus with a dull-spined cactus could result in both sharp- and dull-spined offspring?

Use the figure and the following description to answer the question. In a particular plant, leaf color is controlled by gene locus D. Plants with at least one allele D have dark green leaves, and plants with the homozygous recessive dd genotype have light green leaves. A true-breeding, dark-leaved plant is crossed with a light-leaved one, and the F1 offspring is allowed to self-pollinate. The predicted outcome of the F1 cross is diagrammed in the Punnett square shown in the figure, where 1, 2, 3, and 4 represent the genotypes corresponding to each box within the square. Which of the boxes marked 1-4 correspond to plants with a heterozygous genotype?

Which of the following statements about the law of segregation is correct?

Which of the following scenarios describes an example of epistasis?

In pea plants, the tall phenotype is dominant to the dwarf phenotype. If a heterozygous pea plant is crossed with a homozygous tall pea plant, what is the probability that the offspring will be dwarf in size?

When Mendel crossed yellow-seeded and green-seeded pea plants, all the offspring were yellow-seeded. Which of the following genotypic ratios was expected when Mendel crossed the F1 yellow-seeded plants with green-seeded plants?

Ten plants of the same genotype are planted in a large flower garden. Later that year, some of the ten plants have blue flowers and others have pink flowers. This can be best explained by which of the following statements?

Two true-breeding stocks of pea plants are crossed. One parent has red, axial flowers, and the other has white, terminal flowers; all F1 individuals have red, axial flowers. Among the F2 offspring, what is the probability of producing plants with white axial flowers?

Having polydactyly (extra digits on hands and feet) is a dominant trait. A man has polydactyly. His wife and oldest daughter do not have polydactyly. The couple's second child has polydactyly. What is the probability that their next (third) child will have extra digits?