Exam 39: Laboratory Testing in Coagulation

Laboratory testing for von Willebrand factor contains variables that can result in difficulty in diagnosing the disease.Which of the factors below is identified as a variable that can contribute to this difficulty?

The international normalized ratio (INR) is used to standardize the wide variations in the reagent of prothrombin testing.What is the goal of creating the ISI value?

The platelet function analyzer standardized the bleeding time method by eliminating the variables of the method.Which of the following represents the variables of bleeding time?

A patient has a prolonged APTT with a normal PT.There were no errors in specimen collection.What does this mean for the patient?

Which of the following tests can be used to monitor coumadin therapy?

What preanalytical quality control prospect is necessary when performing platelet aggregation studies?

Justify the need for molecular marker testing in the workup of a hemostatic problem.

List the tests that are commonly utilized in the workup of the following: A)von Willebrand's disease B)Hemophilia A C)Factor VIII inhibitor D)Bernard-Soulier syndrome E)TTP

Which of the following is needed to perform an activated partial thromboplastin time?

What does the administration of recombinant factor VIIa concentrate do to the PT levels?

Choose the correct statement regarding proper specimen collection for coagulation testing from the choices listed below:

A patient has severe liver disease.What test results would you expect?

Which of the following tests does not measure activation of the hemostatic mechanism using markers of fibrin formation and fibrinolysis?

According to the International Society on Thrombosis (ISTH), the guidelines for diagnostic criteria for LA/aPL are the demonstration of which of the following?

A citrated blood sample is tested with the following results: -PT = 60.0 seconds -APTT = 100.0 seconds Pending further testing, what is the most probable reason for these results?

A patient has prolonged PT and APTT.Which of the following tests would not be warranted to follow up these findings?

Why is normal pooled plasma used as the diluent in a mixing study?

What is the purpose of the INR?

The aPTT is the most common procedure used to monitor the unfractionated heparin therapy.Which of the reagents used in the testing provides the activation of the formation of the fibrin clot?