Exam 8: Introduction to Anemia

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A blood sample has moderate spherocytes, schistocytes, and polychromasia on the smear.What would you expect the results of the following to be? A)Bilirubin B)LDH C)Hemoglobin D)Retic count E)M:E ratio

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Bilirubin: elevated
LDH: elevated
Hemoglobin: variable but often decreased
Retic count: elevated
M:E ratio: low in chronic cases.Normal in acute cases.

An instrument printout reveals an RDW of 33.Which of the following would best correlate with those results?

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A

An increased red cell distribution width (RDW) usually indicates what abnormality?

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D

A peripheral blood smear has an even distribution of both normocytic normochromic cells and microcytic hypochromic cells.What is this phenomenon called?

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A patient has hemolytic anemia.An instrument printout reveals a reticulocyte count of 8%, marked polychromasia and moderate schistocytes, and an MCV of 88 fl.What can be concluded about the bone marrow response to this hemolytic anemia?

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Codocytes are associated with all of the following conditions except:

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What staining method can be used to differentiate Pappenheimer bodies from reticulocytes?

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A patient presents with a RPI of greater than 2 and macrocytic morphology of the red blood cells.Which survival defect does this most likely represent?

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How would you differentiate between an acanthocyte and an echinocyte?

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What RBC inclusions cannot be seen with Romanowsky stain but can be visualized with supravital stain?

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Acanthocytes or spur cells have membranes with irregular distribution of spikes.What other significant feature does this cell possess?

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A patient sample had a retic count of 5%.The patient's hematocrit was 25%.Normal hematocrit is 45%.What other bone marrow test(s) could you perform to help determine if the bone marrow is responding to the pancytopenia?

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A patient with a bleeding problem is complaining to her physician about excessive fatigue.Physical examination reveals a thin, pale woman with pale mucosal membranes.Significant CBC findings include an MCV of 70 fl.Based on these findings follow-up testing should be ordered for:

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An instrument printout has an RPI of 1.3, a hemoglobin of 7 g/dL and an MCV of 112 fl.What can be concluded from this?

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CBC results on a pregnant patient indicate an MCV of 112 fl.What would be the most appropriate reflex test?

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Blood flow adaptations to anemia are achieved by increasing the respiration rate and _________________

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Howell-Jolly bodies are red cell inclusions associated with what disease state?

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Red blood cell survival is best measured by which of the following when hemoglobin levels are stable?

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A bone marrow aspirate is hypercellular and has an M:E ratio of 1:4.What can be concluded from this? There is:

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All of the following are classic signs of anemia except:

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