Explain the effects of the following on coagulation testing: A)Clotted sample B)Ratio of blood to anticoagulant 55% D)Greater than 1-hour difference between specimen collection and analysis

Clotted sample: Since factors are consum

Exam 39: Laboratory Testing in Coagulation

Explore all topics

Give the results (prolonged or normal) for the bleeding time, prothrombin time, activated partial thromboplastin time, and thrombin time for a patient on prolonged anticoagulant therapy.

Free

(Essay)

4.7/5

(77)

Question 1

Correct Answer:

Verified

A)BT: Bleeding time assesses primary hemostasis, so prolonged anticoagulant therapy should not affect the BT.
B)PT: If the patient is taking coumadin, the PT time will be prolonged.
C)APTT: If the patient is on heparin, the APTT will be prolonged.
D)TT: Heparin will almost certainly cause a prolonged TT.

Laboratory screening test results strongly suggest heparin contamination.Which of the following tests would help assess this finding? A)DRVVT B)Reptilase time C)APTT D)AT III activity

Free

(Essay)

4.7/5

(82)

Question 2

Correct Answer:

Verified

A patient is admitted with prolonged epistaxis and prolonged bleeding from a recent tooth extraction.Initial screening workup reports prolonged APTT and BT, and abnormal aggregation on the PFA.Which of the following tests would help define the disorder?

Free

(Multiple Choice)

4.7/5

(77)

Question 3

Correct Answer:

Verified

A patient is screened positive for APCR.What does this mean for the patient?

(Multiple Choice)

4.9/5

(75)

Question 4

A patient with a fibrinolytic deficiency would:

(Multiple Choice)

4.9/5

(83)

Question 5

Proper pecimen collection for coagulation testing must be performed to eliminate contamination of substances that will interfere with the test results.Which of the following are considered contaminates for coagulation testing?

(Multiple Choice)

4.8/5

(70)

Question 6

A patient's laboratory coagulation testing results in an immediate correction of the PT and aPTT after mixing studies, and no correction after performing the PT and aPTT after a 2-hour incubation at 37°C.What is the possible deficiency or inhibitor?

(Multiple Choice)

4.8/5

(84)

Question 7

The Thrombin Time is prolonged with a patient having:

(Multiple Choice)

4.9/5

(74)

Question 8

The anticoagulant of 3.2% sodium citrate is preferred over 3.8% because:

(Multiple Choice)

4.8/5

(94)

Question 9

The Prothrombin Time measures the clotting factors in the:

(Multiple Choice)

5.0/5

(75)

Question 10

Using the PRP, platelet-rich plasma, in the aggregation studies of a patient's blood, the results were typical of the RIPA, ristocetin-induced platelet agglutination defect.The RIPA defect was corrected by adding normal plasma to the patient's PRP.In what disease is this seen?

(Multiple Choice)

4.9/5

(86)

Question 11

Explain the clinical significance of a prolonged time with each of the following: A)Bleeding time. B)Prothrombin time. C)Activated partial thromboplastin time. D)Thrombin time.

(Essay)

4.8/5

(81)

Question 12

An outpatient has an INR of 6.5.Previous testing at the same facility had results in the normal range of 2-3 for this patient on long-term anticoagulant therapy.The appropriate next step for the laboratorian would be:

(Multiple Choice)

4.8/5

(84)

Question 13

Interpret the results below. a.PT = 32 sec b.APTT = 92 sec c.TT = 20 sec. What is the most likely reason for these aberrant results?

(Multiple Choice)

4.9/5

(76)

Question 14

Explain the effects of the following on coagulation testing: A)Clotted sample B)Ratio of blood to anticoagulant < 9:1 C)Patient hematocrit >55% D)Greater than 1-hour difference between specimen collection and analysis

(Essay)

4.9/5

(80)

Question 15

Proper collection and processing of coagulation specimens is necessary for optimum results.What should be avoided when processing the sodium citrated specimens for testing?

(Multiple Choice)

4.7/5

(91)

Question 16

Based on the following laboratory data: PT: normal APTT: prolonged Factor VIII: C assay: <1% Which of the following is the most appropriate reflex test?

(Multiple Choice)

4.9/5

(84)

Question 17

A hemophilic patient (Hemophilia A) has a severe bleed and is being treated with Factor VIII concentrate.When testing his post-infusion, the factor VIII level does not increase.The problem could be:

(Multiple Choice)

4.8/5

(90)

Question 18

In performing testing for thrombotic disorders, the ideal testing would be:

(Multiple Choice)

4.8/5

(73)

Question 19

Which of the following tests is used to assess platelet function in vivo?

(Multiple Choice)

4.9/5

(79)

Question 20

Showing 1 - 20 of 39

Exam 39: Laboratory Testing in Coagulation

Give the results (prolonged or normal) for the bleeding time, prothrombin time, activated partial thromboplastin time, and thrombin time for a patient on prolonged anticoagulant therapy.

Laboratory screening test results strongly suggest heparin contamination.Which of the following tests would help assess this finding? A)DRVVT B)Reptilase time C)APTT D)AT III activity

A patient is admitted with prolonged epistaxis and prolonged bleeding from a recent tooth extraction.Initial screening workup reports prolonged APTT and BT, and abnormal aggregation on the PFA.Which of the following tests would help define the disorder?

A patient is screened positive for APCR.What does this mean for the patient?

A patient with a fibrinolytic deficiency would:

Proper pecimen collection for coagulation testing must be performed to eliminate contamination of substances that will interfere with the test results.Which of the following are considered contaminates for coagulation testing?

A patient's laboratory coagulation testing results in an immediate correction of the PT and aPTT after mixing studies, and no correction after performing the PT and aPTT after a 2-hour incubation at 37°C.What is the possible deficiency or inhibitor?

The Thrombin Time is prolonged with a patient having:

The anticoagulant of 3.2% sodium citrate is preferred over 3.8% because:

The Prothrombin Time measures the clotting factors in the:

Using the PRP, platelet-rich plasma, in the aggregation studies of a patient's blood, the results were typical of the RIPA, ristocetin-induced platelet agglutination defect.The RIPA defect was corrected by adding normal plasma to the patient's PRP.In what disease is this seen?

Explain the clinical significance of a prolonged time with each of the following: A)Bleeding time. B)Prothrombin time. C)Activated partial thromboplastin time. D)Thrombin time.

An outpatient has an INR of 6.5.Previous testing at the same facility had results in the normal range of 2-3 for this patient on long-term anticoagulant therapy.The appropriate next step for the laboratorian would be:

Interpret the results below. a.PT = 32 sec b.APTT = 92 sec c.TT = 20 sec. What is the most likely reason for these aberrant results?

Explain the effects of the following on coagulation testing: A)Clotted sample B)Ratio of blood to anticoagulant < 9:1 C)Patient hematocrit >55% D)Greater than 1-hour difference between specimen collection and analysis

Proper collection and processing of coagulation specimens is necessary for optimum results.What should be avoided when processing the sodium citrated specimens for testing?

Based on the following laboratory data: PT: normal APTT: prolonged Factor VIII: C assay: <1% Which of the following is the most appropriate reflex test?

A hemophilic patient (Hemophilia A) has a severe bleed and is being treated with Factor VIII concentrate.When testing his post-infusion, the factor VIII level does not increase.The problem could be:

In performing testing for thrombotic disorders, the ideal testing would be:

Which of the following tests is used to assess platelet function in vivo?

Introduction

Cellular Homeostasis

Hematopoiesis

Structure and Function of Hematopoietic Organs

The Erythrocyte

Hemoglobin

The Leukocyte

Introduction to Anemia

Anemias of Disordered Iron Metabolism and Heme Synthesis

Hemoglobinopaties: Qualitative Defects

Thalassemia

Megaloblastic and Nonmegaloblastic Macrocytic Anemias

Introduction to Hemolytic Anemia

Hemolytic Anemia: Membrane Defects

Hemolytic Anemia: Enzyme Deficiencies

Hemolytic Anemia: Immune Anemias

Hemolytic Anemia: Nonimmune Defects

Nonmalignant Granulocyte and Monocyte Disorders

Nonmalignant Lymphocyte Disorders

Introduction to Hematopoietic Neoplasms

Myeloproliferative Disorders

Myelodysplastic Syndromes

Acute Myeloid Leukemias

Acute Lymphoblastic Leukemias

Lymphoid Malignancies: Chronic Lymphoid Leukemias, Lymphomas, and Plasma Cell Neoplasms

Hematopoietic Stem Cell Transplantation

Morphologic Analysis of Body Fluids in the Hematology Laboratory

Primary Hemostasis

Secondary Hemostasis and Fibrinolysis

Disorders of Primary Hemostasis

Disorders of Secondary Hemostasis

Thrombophilia

Hematology Procedures and Hemostasis

Bone Marrow Examination

Automation in Hematology and Hemostasis

Flow Cytometry

Chromosome Analysis of Hematopoietic and Lymphoid Disorders

Molecular Analysis of Hematologic Diseases

Quality Assessment in the Hematology Laboratory

Filters