Exam 18: Nonmalignant Granulocyte and Monocyte Disorders

A 45-year-old male goes to his physician for a routine checkup.His ANC (absolute neutrophil count) result comes back as 8.5 x 10⁹/L.Which of the following conditions could explain these results?

Which of the following disorders is characterized by a defect in sphingomyelinase, which results in macrophages with a foamy appearance?

How does immediate neutrophilia differ from acute neutrophilia?

A patient's smear shows clumping of neutrophils.The ANC shows a neutropenia. What can be done to obtain a reliable neutrophil count?

Interpret the following results: WBC count 1.4 x 10⁹/L; bone marrow shows myeloid hypoplasia with a decreased M:E ratio of 1:1.There is no history of medications or drug Exposure.What can be concluded from this?

A patient presents with splenomegaly and bone pain.Laboratory findings reveal large macrophages with small eccentric nuclei, and cytoplasm with a wrinkled appearance. Further testing shows leukopenia, thrombocytopenia, and anemia.What is the probable Cause?

A patient has a high fever, leukopenia, thrombocytopenia, and elevated liver enzymes.A blood smear shows WBCs with large basophilic, spherical cellular inclusions.What could be The cause?

Name a type of condition which might cause the following alterations in morphology. a.Toxic granulation b.Vacuolization c.Morulae d.Eosinophilia

A patient presents with neutrophilia of 50 x 10⁹/L with many circulating immature cells.The blood contains many bands, metamyelocytes, myelocytes, promyelocytes, and a rare blast.There are no nucleated erythrocytes present.What disease state is most likely with these results?

A technologist is scanning a blood smear and notices that many of the neutrophils have more than six lobes.Which of the following would be consistent with that finding?

A patient presents with a leukocyte count of 120 x 10⁹/L and splenomegaly.The blood smear reveals a shift to the left with promyelocytes and blasts.The platelets are increased, and the LAP is decreased.Which condition is associated with these results?

Define leukoerythroblastosis, and name a condition in which this is seen.

List three laboratory results that can distinguish a leukemoid reaction from CML.

Which of the following characteristics is associated with the neutrophilia that accompanies bacterial infection?

A patient has a WBC count of > 50 x 10⁹/L with many circulating leukocyte precursors and a normal RBC count.What can be concluded from these findings?

A 45-year-old female came back from a trip abroad having had nausea and diarrhea, and then later muscle aches, fever, and chills.She is admitted to a local hospital, and is diagnosed With trichinosis.Which of the following is most consistent with this disease?

What disease state correlates highly with the presence of cytoplasmic vacuoles in freshly drawn blood?

A peripheral blood smear examination shows many WBCs with many blue-staining round inclusions present.There is thrombocytopenia with giant platelets present.What autosomal dominant disease is associated with these findings?

Acute infection, inflammatory reaction, and administration of glucocorticosteroids may result in:

What causes sea-blue histiocytosis, and how is the sea-blue histiocyte identified?