Question 1

What disease state is associated with helmet cells?

Accepted Answer

A) Diabetes 
B) Iron deficiency 
C) Heart valve hemolysis 
D) Thalassemia 
A) Diabetes 
B) Iron deficiency 
C) Heart valve hemolysis 
D) Thalassemia

Question 2

An instrument printout indicates an MCV of 63 fl and an MCHC of 26 g/dl.How will the red cells appear under the microscope?

Accepted Answer

A) Normocytic, normochromic 
B) Macrocytic, normochromic 
C) Microcytic, hypochromic 
D) Normocytic, hypochromic 
A) Normocytic, normochromic 
B) Macrocytic, normochromic 
C) Microcytic, hypochromic 
D) Normocytic, hypochromic

Question 3

Which RBC inclusion is characterized by diffusely staining RNA precipitate that can be seen when blood is stained with Wright's stain?

Accepted Answer

A) Heinz bodies 
B) Pappenheimer bodies 
C) Howell-Jolly bodies 
D) Basophilic stippling 
A) Heinz bodies 
B) Pappenheimer bodies 
C) Howell-Jolly bodies 
D) Basophilic stippling

Question 4

What is the RPI for this patient with a reticulocyte count of 5% and hematocrit of 25%.Normal hematocrit is 45%.

Accepted Answer

A) 2.39 
B) 2.59 
C) 1.39 
D) 4.50 
A) 2.39 
B) 2.59 
C) 1.39 
D) 4.50

Question 5

Remnants of DNA inside an RBC produce which type of inclusion?

Accepted Answer

A) Howell-Jolly bodies 
B) Basophilic stippling 
C) Cabot rings 
D) Pappenheimer bodies 
A) Howell-Jolly bodies 
B) Basophilic stippling 
C) Cabot rings 
D) Pappenheimer bodies

Question 6

A patient sample had a retic count of 5%.The patient's hematocrit was 25%.Normal hematocrit is 45%.What is the corrected reticulocyte count?

Accepted Answer

A) 3.50% 
B) 2.78% 
C) 5% 
D) 10% 
A) 3.50% 
B) 2.78% 
C) 5% 
D) 10%

Question 7

What test is the most sensitive and specific for detecting iron-deficiency anemia?

Accepted Answer

A) Vitamin B₁₂ assay 
B) Ferritin 
C) RDW 
D) Transferrin saturation 
A) Vitamin B₁₂ assay 
B) Ferritin 
C) RDW 
D) Transferrin saturation

Question 8

Which of the following laboratory values would best correlate with moderate polychromasia on the peripheral blood smear?

Accepted Answer

A) A low RBC count 
B) A retic count of 8% 
C) Schistocytes on the PB smear 
D) A low PLT count 
A) A low RBC count 
B) A retic count of 8% 
C) Schistocytes on the PB smear 
D) A low PLT count

Question 9

An apparent pancytopenia is noted in a patient's CBC results.A bone marrow aspirate is performed, and the M:E results are 2:1.Do these results make sense? Why or why not?

Accepted Answer

Yes they do.The M:E ratio exam

Question 10

All of the following laboratory tests can be used for evaluation of hemolysis except:

Accepted Answer

A) Haptoglobin. 
B) Hemopexin. 
C) Total protein. 
D) Bilirubin. 
A) Haptoglobin. 
B) Hemopexin. 
C) Total protein. 
D) Bilirubin.

Question 11

What is one of the disease states associated with the presence of target cells?

Accepted Answer

A) Sickle cell anemia 
B) Thalassemia 
C) Uremia 
D) Hemolytic anemia 
A) Sickle cell anemia 
B) Thalassemia 
C) Uremia 
D) Hemolytic anemia

Question 12

Why do we see Howell-Jolly bodies in patients who have had a splenectomy? Explain your answer.

Accepted Answer

The spleen is responsible for

Question 13

How does the mean cell volume value classify cells?

Accepted Answer

A) Normochromic, hypochromic, and hyperchromic 
B) Normocytic, microcytic, macrocytic 
C) Poikilocytosis 
D) Polychromasia 
A) Normochromic, hypochromic, and hyperchromic 
B) Normocytic, microcytic, macrocytic 
C) Poikilocytosis 
D) Polychromasia

Question 14

A patient sample has an RBC count of 4.30 x 1012 ? This is a superscript ?
/L and a reticulocyte count of 4%.What is the absolute retic count?
This is a superscript

Accepted Answer

A) 142 x 109/L 
B) 172 x 109/L 
C) 350 x 109/L 
D) 90 x 109/L 
A) 142 x 109/L 
B) 172 x 109/L 
C) 350 x 109/L 
D) 90 x 109/L

Question 15

Patient results indicate an RPI of 1.8 and an MCV of 109 fl.Do these results make sense? Why or why not?

Accepted Answer

Yes they do.This is the classic picture

Exam 8: Introduction to Anemia

What disease state is associated with helmet cells?

An instrument printout indicates an MCV of 63 fl and an MCHC of 26 g/dl.How will the red cells appear under the microscope?

Which RBC inclusion is characterized by diffusely staining RNA precipitate that can be seen when blood is stained with Wright's stain?

What is the RPI for this patient with a reticulocyte count of 5% and hematocrit of 25%.Normal hematocrit is 45%.

Remnants of DNA inside an RBC produce which type of inclusion?

A patient sample had a retic count of 5%.The patient's hematocrit was 25%.Normal hematocrit is 45%.What is the corrected reticulocyte count?

What test is the most sensitive and specific for detecting iron-deficiency anemia?

Which of the following laboratory values would best correlate with moderate polychromasia on the peripheral blood smear?

An apparent pancytopenia is noted in a patient's CBC results.A bone marrow aspirate is performed, and the M:E results are 2:1.Do these results make sense? Why or why not?

All of the following laboratory tests can be used for evaluation of hemolysis except:

What is one of the disease states associated with the presence of target cells?

Why do we see Howell-Jolly bodies in patients who have had a splenectomy? Explain your answer.

How does the mean cell volume value classify cells?

A patient sample has an RBC count of 4.30 x 1012 ? This is a superscript ? /L and a reticulocyte count of 4%.What is the absolute retic count? This is a superscript

Patient results indicate an RPI of 1.8 and an MCV of 109 fl.Do these results make sense? Why or why not?

Introduction

Cellular Homeostasis

Hematopoiesis

Structure and Function of Hematopoietic Organs

The Erythrocyte

Hemoglobin

The Leukocyte

Anemias of Disordered Iron Metabolism and Heme Synthesis

Hemoglobinopaties: Qualitative Defects

Thalassemia

Megaloblastic and Nonmegaloblastic Macrocytic Anemias

Introduction to Hemolytic Anemia

Hemolytic Anemia: Membrane Defects

Hemolytic Anemia: Enzyme Deficiencies

Hemolytic Anemia: Immune Anemias

Hemolytic Anemia: Nonimmune Defects

Nonmalignant Granulocyte and Monocyte Disorders

Nonmalignant Lymphocyte Disorders

Introduction to Hematopoietic Neoplasms

Myeloproliferative Disorders

Myelodysplastic Syndromes

Acute Myeloid Leukemias

Acute Lymphoblastic Leukemias

Lymphoid Malignancies: Chronic Lymphoid Leukemias, Lymphomas, and Plasma Cell Neoplasms

Hematopoietic Stem Cell Transplantation

Morphologic Analysis of Body Fluids in the Hematology Laboratory

Primary Hemostasis

Secondary Hemostasis and Fibrinolysis

Disorders of Primary Hemostasis

Disorders of Secondary Hemostasis

Thrombophilia

Hematology Procedures and Hemostasis

Bone Marrow Examination

Automation in Hematology and Hemostasis

Flow Cytometry

Chromosome Analysis of Hematopoietic and Lymphoid Disorders

Molecular Analysis of Hematologic Diseases

Laboratory Testing in Coagulation

Quality Assessment in the Hematology Laboratory

Filters

A patient sample has an RBC count of 4.30 x 10¹² ? This is a superscript ? /L and a reticulocyte count of 4%.What is the absolute retic count? This is a superscript