Question 1

Which of the following is not typically found on a bone marrow report?

Accepted Answer

A) Patient's insurance information 
B) Patient's biographical data 
C) Patient's clinical diagnosis 
D) Relevant therapeutic information 
A) Patient's insurance information 
B) Patient's biographical data 
C) Patient's clinical diagnosis 
D) Relevant therapeutic information

Question 2

What is the calculation to determine the normal expected cellularity range in an adult?

Accepted Answer

A) Subtract the patient's age from 100% and add/subtract 20%. 
B) Subtract the patient's age from 100% and add/subtract 10%. 
C) Subtract the patient's age from 100% and add/subtract 30%. 
D) Subtract the patient's age from 100% and add/subtract 50%. 
A) Subtract the patient's age from 100% and add/subtract 20%. 
B) Subtract the patient's age from 100% and add/subtract 10%. 
C) Subtract the patient's age from 100% and add/subtract 30%. 
D) Subtract the patient's age from 100% and add/subtract 50%.

Question 3

A physician performing a bone marrow biopsy on a patient suspected of having acute leukemia was unable to obtain any aspirate, but was able to obtain two core biopsies.What is the best way for the clinical laboratorian to use the material obtained?

Accepted Answer

A) Place both core biopsies in formalin and process one immediately; save the other for ancillary tests. 
B) Place one core biopsy in formalin and freeze the second one at -70°C. 
C) Place one core biopsy in formalin after making touch imprints; put the second in saline. 
D) Place both core biopsies in saline; freeze one at 0°C, and process the other immediately. 
A) Place both core biopsies in formalin and process one immediately; save the other for ancillary tests. 
B) Place one core biopsy in formalin and freeze the second one at -70°C. 
C) Place one core biopsy in formalin after making touch imprints; put the second in saline. 
D) Place both core biopsies in saline; freeze one at 0°C, and process the other immediately.

Question 4

How many cells typically are counted when performing a bone marrow differential?

Accepted Answer

A) 100 
B) 2000 
C) 1000 
D) 10 of each lineage 
A) 100 
B) 2000 
C) 1000 
D) 10 of each lineage

Question 5

Compare Prussian blue iron stain results in the following disorders and explain your answers:
A)Iron-deficiency anemia
B)Anemia of chronic disease.
C)Thalassemia
D)Sideroblastic anemia

Accepted Answer

Iron-deficiency anemia: decreased; the e

Question 6

A normal M:E ratio is about 3:1.Why are there three times more myeloid precursors than erythroid precursors in the bone marrow?

Accepted Answer

A) Because the body needs more cells to fight infection than to transport oxygen 
B) Because the life cycle of a WBC is much longer than that of an RBC 
C) Because WBCs undergo more steps in hematopoiesis than do RBCs 
D) Because the life cycle of a WBC is much shorter than that of an RBC 
A) Because the body needs more cells to fight infection than to transport oxygen 
B) Because the life cycle of a WBC is much longer than that of an RBC 
C) Because WBCs undergo more steps in hematopoiesis than do RBCs 
D) Because the life cycle of a WBC is much shorter than that of an RBC

Question 7

What is the overall cellularity range of a bone marrow in a 35-year-old female patient?

Accepted Answer

A) 35-45% 
B) 55-75% 
C) 50-60% 
D) 70-80% 
A) 35-45% 
B) 55-75% 
C) 50-60% 
D) 70-80%

Question 8

Name disorders in which the following should be included in the workup of a hematologic disorder.Explain why they are used.
A)Flow cytometry
B)Cytogenetics
C)Molecular genetics
D)Cytochemical staining

Accepted Answer

Flow cytometry: malignant lymphomas and

Question 9

Name five distinguishable characteristics that will help differentiate between benign lymphoid aggregates and malignant lymphoma.

Accepted Answer

-Benign lymphoid aggregates: nonparatrab

Question 10

If a bone marrow aspiration results in a dry tap, how are the slides prepared?

Accepted Answer

A) Touch imprints of the core biopsy 
B) Core biopsy washings 
C) Re-aspiration 
D) Histologic embedded paraffin blocks 
A) Touch imprints of the core biopsy 
B) Core biopsy washings 
C) Re-aspiration 
D) Histologic embedded paraffin blocks

Question 11

What is the role of the hematology technologist in bone marrow evaluation?

Accepted Answer

A) Perform the bone marrow aspirate procedure. 
B) Administer anesthetic in preparation of the procedure. 
C) Make bone marrow smears after collection. 
D) Report the results of the bone marrow examination to the attending physician. 
A) Perform the bone marrow aspirate procedure. 
B) Administer anesthetic in preparation of the procedure. 
C) Make bone marrow smears after collection. 
D) Report the results of the bone marrow examination to the attending physician.

Question 12

All of the following are sites for bone marrow specimen collection EXCEPT the:

Accepted Answer

A) Tibia. 
B) Femur. 
C) Sternum. 
D) Iliac crest. 
A) Tibia. 
B) Femur. 
C) Sternum. 
D) Iliac crest.

Question 13

All of the following are conditions in which a bone marrow aspirate is indicated EXCEPT:

Accepted Answer

A) Diagnosing infections of known origin. 
B) Staging malignancies. 
C) Evaluation of unexplained cytopenia. 
D) Primary diagnosis of hematologic malignancies. 
A) Diagnosing infections of known origin. 
B) Staging malignancies. 
C) Evaluation of unexplained cytopenia. 
D) Primary diagnosis of hematologic malignancies.

Question 14

What are the main differences in uses between a core biopsy specimen and aspirate specimen?

Accepted Answer

-The aspirate is good for assessment of

Exam 34: Bone Marrow Examination

Which of the following is not typically found on a bone marrow report?

What is the calculation to determine the normal expected cellularity range in an adult?

A physician performing a bone marrow biopsy on a patient suspected of having acute leukemia was unable to obtain any aspirate, but was able to obtain two core biopsies.What is the best way for the clinical laboratorian to use the material obtained?

How many cells typically are counted when performing a bone marrow differential?

Compare Prussian blue iron stain results in the following disorders and explain your answers: A)Iron-deficiency anemia B)Anemia of chronic disease. C)Thalassemia D)Sideroblastic anemia

A normal M:E ratio is about 3:1.Why are there three times more myeloid precursors than erythroid precursors in the bone marrow?

What is the overall cellularity range of a bone marrow in a 35-year-old female patient?

Name disorders in which the following should be included in the workup of a hematologic disorder.Explain why they are used. A)Flow cytometry B)Cytogenetics C)Molecular genetics D)Cytochemical staining

Name five distinguishable characteristics that will help differentiate between benign lymphoid aggregates and malignant lymphoma.

If a bone marrow aspiration results in a dry tap, how are the slides prepared?

What is the role of the hematology technologist in bone marrow evaluation?

All of the following are sites for bone marrow specimen collection EXCEPT the:

All of the following are conditions in which a bone marrow aspirate is indicated EXCEPT:

What are the main differences in uses between a core biopsy specimen and aspirate specimen?

Introduction

Cellular Homeostasis

Hematopoiesis

Structure and Function of Hematopoietic Organs

The Erythrocyte

Hemoglobin

The Leukocyte

Introduction to Anemia

Anemias of Disordered Iron Metabolism and Heme Synthesis

Hemoglobinopaties: Qualitative Defects

Thalassemia

Megaloblastic and Nonmegaloblastic Macrocytic Anemias

Introduction to Hemolytic Anemia

Hemolytic Anemia: Membrane Defects

Hemolytic Anemia: Enzyme Deficiencies

Hemolytic Anemia: Immune Anemias

Hemolytic Anemia: Nonimmune Defects

Nonmalignant Granulocyte and Monocyte Disorders

Nonmalignant Lymphocyte Disorders

Introduction to Hematopoietic Neoplasms

Myeloproliferative Disorders

Myelodysplastic Syndromes

Acute Myeloid Leukemias

Acute Lymphoblastic Leukemias

Lymphoid Malignancies: Chronic Lymphoid Leukemias, Lymphomas, and Plasma Cell Neoplasms

Hematopoietic Stem Cell Transplantation

Morphologic Analysis of Body Fluids in the Hematology Laboratory

Primary Hemostasis

Secondary Hemostasis and Fibrinolysis

Disorders of Primary Hemostasis

Disorders of Secondary Hemostasis

Thrombophilia

Hematology Procedures and Hemostasis

Automation in Hematology and Hemostasis

Flow Cytometry

Chromosome Analysis of Hematopoietic and Lymphoid Disorders

Molecular Analysis of Hematologic Diseases

Laboratory Testing in Coagulation

Quality Assessment in the Hematology Laboratory

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