Question 1

Primitive erythropoiesis in the yolk sac is important to what process?

Accepted Answer

A) Transportation of oxygen to developing tissue 
B) Development of immunity 
C) Liver development 
D) Cellular differentiation 
A) Transportation of oxygen to developing tissue 
B) Development of immunity 
C) Liver development 
D) Cellular differentiation

Question 2

Which of the following is considered a MALT tissue?

Accepted Answer

A) Lymph node 
B) Thymus 
C) Tonsils 
D) Bone marrow 
A) Lymph node 
B) Thymus 
C) Tonsils 
D) Bone marrow

Question 3

What would you expect to see on microscopic examination of a stained blood smear if the patient has had a splenectomy and why?

Accepted Answer

You would expect to see erythrocyte incl

Question 4

Where are plasma cells located in the lymph node?

Accepted Answer

A) Cortex 
B) Medulla 
C) Germinal centers 
D) Peripheral zone 
A) Cortex 
B) Medulla 
C) Germinal centers 
D) Peripheral zone

Question 5

A diagnosis of hypersplenism is made when which conditions are met?

Accepted Answer

A) Presence of anemia, leukopenia, or thrombocytopenia 
B) Cytopenia in both the peripheral blood and bone marrow, and correction of cytopenia after splenectomy 
C) Anemia and cytopenia in the peripheral blood, existence of a cellular or hyperplastic bone marrow corresponding to the peripheral blood cytopenia, and splenomegaly 
D) Cytopenia in both the peripheral blood and bone marrow 
A) Presence of anemia, leukopenia, or thrombocytopenia 
B) Cytopenia in both the peripheral blood and bone marrow, and correction of cytopenia after splenectomy 
C) Anemia and cytopenia in the peripheral blood, existence of a cellular or hyperplastic bone marrow corresponding to the peripheral blood cytopenia, and splenomegaly 
D) Cytopenia in both the peripheral blood and bone marrow

Question 6

Predict the size of the thymus in a mature adult in comparison with an infant thymus.

Accepted Answer

A) The adult thymus will be the same size as the infant thymus. 
B) The adult thymus will be larger than the infant thymus. 
C) The adult thymus will be smaller than the infant thymus. 
D) It cannot be determined. 
A) The adult thymus will be the same size as the infant thymus. 
B) The adult thymus will be larger than the infant thymus. 
C) The adult thymus will be smaller than the infant thymus. 
D) It cannot be determined.

Question 7

The process of culling and pitting occurs in the spleen's:

Accepted Answer

A) Germinal centers. 
B) Follicles. 
C) Vascular sinuses. 
D) Red pulp cords. 
A) Germinal centers. 
B) Follicles. 
C) Vascular sinuses. 
D) Red pulp cords.

Question 8

In cases where the bone marrow is compromised, hematopoiesis can resume in other organs.What is this phenomenon called, and what organs have this ability?

Accepted Answer

A) Hematopoiesis; lymph node and spleen 
B) Extramedullary hematopoiesis; liver and spleen 
C) Nuclear asynchrony; thymus and spleen 
D) Diapedesis; blood vessels and brain 
A) Hematopoiesis; lymph node and spleen 
B) Extramedullary hematopoiesis; liver and spleen 
C) Nuclear asynchrony; thymus and spleen 
D) Diapedesis; blood vessels and brain

Question 9

What feature separates primary from secondary lymphoid tissue?

Accepted Answer

A) Primary lymph tissue can replace secondary. 
B) Primary lymphoid tissue is necessary to the secondary lymphoid tissue process. 
C) Immunocompetent T and B cells are found only in secondary lymphoid tissue. 
D) Immunocompetent T and B cells are found only in primary lymphoid tissue. 
A) Primary lymph tissue can replace secondary. 
B) Primary lymphoid tissue is necessary to the secondary lymphoid tissue process. 
C) Immunocompetent T and B cells are found only in secondary lymphoid tissue. 
D) Immunocompetent T and B cells are found only in primary lymphoid tissue.

Question 10

Hypersplenism associated with compensatory hypertrophy of the spleen is associated with:

Accepted Answer

A) Neoplasms where malignant cells occupy much of the splenic space. 
B) Congestive heart failure. 
C) Liver cirrhosis with portal hypertension. 
D) Infection and inflammatory diseases. 
A) Neoplasms where malignant cells occupy much of the splenic space. 
B) Congestive heart failure. 
C) Liver cirrhosis with portal hypertension. 
D) Infection and inflammatory diseases.

Question 11

The hematopoietic compartment of the bone marrow contains what components?

Accepted Answer

A) Connective tissue and stroma 
B) Hematopoietic cells and stroma 
C) Tissues and vasculature 
D) Tissues and stroma 
A) Connective tissue and stroma 
B) Hematopoietic cells and stroma 
C) Tissues and vasculature 
D) Tissues and stroma

Question 12

The primary site of hematopoiesis in a 4-month-old maturing fetus is:

Accepted Answer

A) Liver. 
B) Spleen. 
C) Bone marrow. 
D) Lymph node. 
A) Liver. 
B) Spleen. 
C) Bone marrow. 
D) Lymph node.

Question 13

All of the following contribute to a diagnosis of hypersplenism except:

Accepted Answer

A) Cytopenia in the peripheral blood. 
B) Hyperplastic marrow. 
C) Hepatomegaly. 
D) Splenomegaly. 
A) Cytopenia in the peripheral blood. 
B) Hyperplastic marrow. 
C) Hepatomegaly. 
D) Splenomegaly.

Question 14

What is the primary hematopoietic function of the spleen?

Accepted Answer

A) Extramedullary hematopoiesis 
B) Lymphatic drainage 
C) Culling and pitting 
D) T cell maturation 
A) Extramedullary hematopoiesis 
B) Lymphatic drainage 
C) Culling and pitting 
D) T cell maturation

Exam 4: Structure and Function of Hematopoietic Organs

Primitive erythropoiesis in the yolk sac is important to what process?

Which of the following is considered a MALT tissue?

What would you expect to see on microscopic examination of a stained blood smear if the patient has had a splenectomy and why?

Where are plasma cells located in the lymph node?

A diagnosis of hypersplenism is made when which conditions are met?

Predict the size of the thymus in a mature adult in comparison with an infant thymus.

The process of culling and pitting occurs in the spleen's:

In cases where the bone marrow is compromised, hematopoiesis can resume in other organs.What is this phenomenon called, and what organs have this ability?

What feature separates primary from secondary lymphoid tissue?

Hypersplenism associated with compensatory hypertrophy of the spleen is associated with:

The hematopoietic compartment of the bone marrow contains what components?

The primary site of hematopoiesis in a 4-month-old maturing fetus is:

All of the following contribute to a diagnosis of hypersplenism except:

What is the primary hematopoietic function of the spleen?

Introduction

Cellular Homeostasis

Hematopoiesis

The Erythrocyte

Hemoglobin

The Leukocyte

Introduction to Anemia

Anemias of Disordered Iron Metabolism and Heme Synthesis

Hemoglobinopaties: Qualitative Defects

Thalassemia

Megaloblastic and Nonmegaloblastic Macrocytic Anemias

Introduction to Hemolytic Anemia

Hemolytic Anemia: Membrane Defects

Hemolytic Anemia: Enzyme Deficiencies

Hemolytic Anemia: Immune Anemias

Hemolytic Anemia: Nonimmune Defects

Nonmalignant Granulocyte and Monocyte Disorders

Nonmalignant Lymphocyte Disorders

Introduction to Hematopoietic Neoplasms

Myeloproliferative Disorders

Myelodysplastic Syndromes

Acute Myeloid Leukemias

Acute Lymphoblastic Leukemias

Lymphoid Malignancies: Chronic Lymphoid Leukemias, Lymphomas, and Plasma Cell Neoplasms

Hematopoietic Stem Cell Transplantation

Morphologic Analysis of Body Fluids in the Hematology Laboratory

Primary Hemostasis

Secondary Hemostasis and Fibrinolysis

Disorders of Primary Hemostasis

Disorders of Secondary Hemostasis

Thrombophilia

Hematology Procedures and Hemostasis

Bone Marrow Examination

Automation in Hematology and Hemostasis

Flow Cytometry

Chromosome Analysis of Hematopoietic and Lymphoid Disorders

Molecular Analysis of Hematologic Diseases

Laboratory Testing in Coagulation

Quality Assessment in the Hematology Laboratory

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