Exam 18: Control of Gene Expression

Use the following scenario to answer the following questions. Suppose an experimenter becomes proficient with a technique that allows her to move DNA sequences within a prokaryotic genome. -If she moves the repressor gene (lac I), along with its promoter, to a position at some several thousand base pairs away from its normal position, which will you expect to occur?

A researcher found a method she could use to manipulate and quantify phosphorylation and methylation in embryonic cells in culture. In one set of experiments using this procedure in Drosophila, she was readily successful in increasing phosphorylation of amino acids adjacent to methylated amino acids in histone tails. Which of the following results would she most likely see?

The gene for which protein would most likely be expressed as a result of MyoD activity?

Tumor suppressor genes

This binds to a site in the DNA far from the promoter to stimulate transcription:

Which of the following statements is True about stem cells?

The cancer-causing forms of the Ras protein are involved in which of the following processes?

A mutation in this section of DNA could influence the binding of RNA polymerase to the DNA:

Forms of the ras protein found in tumors usually cause which of the following?

Use the following scenario to answer the following questions. Suppose an experimenter becomes proficient with a technique that allows her to move DNA sequences within a prokaryotic genome. -If glucose is available in the environment of E. coli, the cell responds with very low concentration of cAMP. When the cAMP increases in concentration, it binds to CAP. Which of the following would you expect would then be a measurable effect?

Which of the following mechanisms is (are)used to coordinately control the expression of multiple, related genes in eukaryotic cells?

Approximately what proportion of the DNA in the human genome codes for proteins or functional RNA?

The product of the bicoid gene in Drosophila could be considered a(n)

In both eukaryotes and prokaryotes, gene expression is primarily regulated at the level of

This can inhibit transcription by blocking the binding of positively acting transcription factors to the DNA:

How does active CAP induce expression of the genes of the lactose operon?

Transcription factors in eukaryotes usually have DNA binding domains as well as other domains also specific for binding. In general, which of the following would you expect many of them to be able to bind?

This protein is produced by a regulatory gene:

The MyoD protein

Absence of bicoid mRNA from a Drosophila egg leads to the absence of anterior larval body parts and mirror-image duplication of posterior parts. This is evidence that the product of the bicoid gene