Question 1

In prokaryotes, the enzyme that replicates the leading strand is _______.

Accepted Answer

The answer of In prokaryotes, the enzyme that replicates the...

Question 2

In bacteria, the enzyme that removes the RNA primers is called

Accepted Answer

A)  DNA ligase. 
B)  primase. 
C)  reverse transcriptase. 
D)  helicase. 
E)  DNA polymerase I. 
A)  DNA ligase. 
B)  primase. 
C)  reverse transcriptase. 
D)  helicase. 
E)  DNA polymerase I.

Question 3

In eukaryotic cells, each chromosome has

Accepted Answer

A)  one origin of replication. 
B)  two origins of replication. 
C)  many origins of replication. 
D)  only one origin of replication per nucleus. 
E)  None of the above 
A)  one origin of replication. 
B)  two origins of replication. 
C)  many origins of replication. 
D)  only one origin of replication per nucleus. 
E)  None of the above

Question 4

The strands that make up DNA are antiparallel. This means that

Accepted Answer

A)  one strand is positively charged, and the other is negatively charged. 
B)  the base pairings create unequal spacing between the two DNA strands. 
C)  the 5´-to-3´ direction of one strand is counter to the 5´-to-3´ direction of the other strand. 
D)  the twisting of the DNA molecule has shifted the two strands. 
E)  purines bond with purines and pyrimidines bond with pyrimidines. 
A)  one strand is positively charged, and the other is negatively charged. 
B)  the base pairings create unequal spacing between the two DNA strands. 
C)  the 5´-to-3´ direction of one strand is counter to the 5´-to-3´ direction of the other strand. 
D)  the twisting of the DNA molecule has shifted the two strands. 
E)  purines bond with purines and pyrimidines bond with pyrimidines.

Question 5

Experiments by Avery, MacLeod, and McCarty supported DNA as the genetic material by showing that

Accepted Answer

A)  both protein and DNA samples provided the transforming factor. 
B)  DNA has to be destroyed by DNase in order to transform the R bacteria. 
C)  DNA is not complex enough to be the genetic material. 
D)  only samples with DNA provided transforming activity. 
E)  even though DNA is molecularly simple, it provides adequate variation to act as the genetic material. 
A)  both protein and DNA samples provided the transforming factor. 
B)  DNA has to be destroyed by DNase in order to transform the R bacteria. 
C)  DNA is not complex enough to be the genetic material. 
D)  only samples with DNA provided transforming activity. 
E)  even though DNA is molecularly simple, it provides adequate variation to act as the genetic material.

Question 6

What is the correct order of the following events in the excision repair of DNA? (1) Base-paired DNA is made complementary to the template.
(2) Damaged bases are recognized.
(3) DNA ligase seals the new strand to existing DNA.
(4) Part of a single strand is excised.

Accepted Answer

A)  1; 2; 3; 4 
B)  2; 1; 3; 4 
C)  2; 4; 1; 3 
D)  3; 4; 2; 1 
E)  4; 2; 3; 1 
A)  1; 2; 3; 4 
B)  2; 1; 3; 4 
C)  2; 4; 1; 3 
D)  3; 4; 2; 1 
E)  4; 2; 3; 1

Question 7

The primary function of DNA polymerase is to

Accepted Answer

A)  add nucleotides to the growing daughter strand. 
B)  seal nicks along the sugar-phosphate backbone of the daughter strand. 
C)  unwind the parent DNA double helix. 
D)  generate primers to initiate DNA synthesis. 
E)  prevent reassociation of the denatured parental DNA strands. 
A)  add nucleotides to the growing daughter strand. 
B)  seal nicks along the sugar-phosphate backbone of the daughter strand. 
C)  unwind the parent DNA double helix. 
D)  generate primers to initiate DNA synthesis. 
E)  prevent reassociation of the denatured parental DNA strands.

Question 8

The Hershey-Chase experiment

Accepted Answer

A)  proved that DNA replication is semiconservative. 
B)  used 32P to label protein. 
C)  used 35S to label DNA. 
D)  helped prove that DNA is the genetic molecule. 
E)  Both b and c 
A)  proved that DNA replication is semiconservative. 
B)  used 32P to label protein. 
C)  used 35S to label DNA. 
D)  helped prove that DNA is the genetic molecule. 
E)  Both b and c

Question 9

Because the DNA molecule is continuous, nucleotide pair after nucleotide pair, their information must lie in the _______ sequence of the nitrogenous bases.

Accepted Answer

The answer of Because the DNA molecule is continuous, nucleotide...

Question 10

The purines take up (more/less) _______ space in the center of a DNA molecule than the pyrimidines do.

Accepted Answer

The answer of The purines take up (more/less) _______ space...

Question 11

The role of DNA ligase in DNA replication is to

Accepted Answer

A)  add more nucleotides to the growing strand one at a time. 
B)  open up the two DNA strands to expose template strands. 
C)  ligate base to sugar to phosphate in a nucleotide. 
D)  bond Okazaki fragments to one another. 
E)  remove incorrectly paired bases. 
A)  add more nucleotides to the growing strand one at a time. 
B)  open up the two DNA strands to expose template strands. 
C)  ligate base to sugar to phosphate in a nucleotide. 
D)  bond Okazaki fragments to one another. 
E)  remove incorrectly paired bases.

Question 12

Refer to the following diagram of DNA complementary base pairing below. Which of the following bases would pair (from top to bottom) with the exposed 3´ end strand?

Accepted Answer

A)  GACT 
B)  TCGA 
C)  AGCT 
D)  TAGC 
E)  ATCG 
A)  GACT 
B)  TCGA 
C)  AGCT 
D)  TAGC 
E)  ATCG

Question 13

The enzyme DNA ligase is required continuously during DNA replication because

Accepted Answer

A)  fragments of the leading strand must be joined together. 
B)  fragments of the lagging strand must be joined together. 
C)  the parental strands must be joined back together. 
D)  3'-deoxynucleoside triphosphates must be converted to 5'-deoxynucleoside triphosphates. 
E)  the complex of proteins that work together at the replication fork must be kept from falling apart. 
A)  fragments of the leading strand must be joined together. 
B)  fragments of the lagging strand must be joined together. 
C)  the parental strands must be joined back together. 
D)  3'-deoxynucleoside triphosphates must be converted to 5'-deoxynucleoside triphosphates. 
E)  the complex of proteins that work together at the replication fork must be kept from falling apart.

Question 14

The X-ray crystallographs of the English chemist _______ were essential for the discovery of the structure of the DNA molecule.

Accepted Answer

The answer of The X-ray crystallographs of the English chemist...

Question 15

Which of the following statements about mismatch repair of DNA is true?

Accepted Answer

A)  The DNA is scanned for any base-pairing mismatches after methyl groups are added to guanines. 
B)  Errors in replication made by DNA polymerase are corrected on the unmethylated strand. 
C)  All abnormal bases are always removed. 
D)  Repairs from damage caused by high-energy radiation are made. 
E)  Mismatch repair occurs as each strand of DNA is being replicated. 
A)  The DNA is scanned for any base-pairing mismatches after methyl groups are added to guanines. 
B)  Errors in replication made by DNA polymerase are corrected on the unmethylated strand. 
C)  All abnormal bases are always removed. 
D)  Repairs from damage caused by high-energy radiation are made. 
E)  Mismatch repair occurs as each strand of DNA is being replicated.

Question 16

The maestro of the replication fork is _______.

Accepted Answer

proliferat

Question 17

The _______ function of DNA polymerase reduces the number of mistakes by the square of the frequency of the error rate.

Accepted Answer

The answer of The _______ function of DNA polymerase reduces...

Question 18

The structure of DNA is characterized by a

Accepted Answer

A)  right- or left-handed double helix and antiparallel strands. 
B)  right-handed double helix and antiparallel strands. 
C)  right-handed single helix. 
D)  right-handed single helix and parallel strands. 
E)  All of the above 
A)  right- or left-handed double helix and antiparallel strands. 
B)  right-handed double helix and antiparallel strands. 
C)  right-handed single helix. 
D)  right-handed single helix and parallel strands. 
E)  All of the above

Question 19

The rules formulated by Erwin Chargaff state that

Accepted Answer

A)  A = T and G = C in any molecule of DNA. 
B)  A = C and G = T in any molecule of DNA. 
C)  A = G and C = T in any molecule of DNA. 
D)  A = U and G = C in any molecule of RNA. 
E)  DNA and RNA are made up of the same four nitrogenous bases. 
A)  A = T and G = C in any molecule of DNA. 
B)  A = C and G = T in any molecule of DNA. 
C)  A = G and C = T in any molecule of DNA. 
D)  A = U and G = C in any molecule of RNA. 
E)  DNA and RNA are made up of the same four nitrogenous bases.

Question 20

The Hershey-Chase experiment persuaded most scientists that

Accepted Answer

A)  bacteria can be transformed. 
B)  DNA is indeed the carrier of hereditary information. 
C)  DNA replication is semiconservative. 
D)  the transforming principle requires host factors. 
E)  All of the above 
A)  bacteria can be transformed. 
B)  DNA is indeed the carrier of hereditary information. 
C)  DNA replication is semiconservative. 
D)  the transforming principle requires host factors. 
E)  All of the above

Exam 13: Dna and Its Role in Heredity

In prokaryotes, the enzyme that replicates the leading strand is _______.

In bacteria, the enzyme that removes the RNA primers is called

In eukaryotic cells, each chromosome has

The strands that make up DNA are antiparallel. This means that

Experiments by Avery, MacLeod, and McCarty supported DNA as the genetic material by showing that

What is the correct order of the following events in the excision repair of DNA? (1) Base-paired DNA is made complementary to the template. (2) Damaged bases are recognized. (3) DNA ligase seals the new strand to existing DNA. (4) Part of a single strand is excised.

The primary function of DNA polymerase is to

The Hershey-Chase experiment

Because the DNA molecule is continuous, nucleotide pair after nucleotide pair, their information must lie in the _______ sequence of the nitrogenous bases.

The purines take up (more/less) _______ space in the center of a DNA molecule than the pyrimidines do.

The role of DNA ligase in DNA replication is to

Refer to the following diagram of DNA complementary base pairing below. Which of the following bases would pair (from top to bottom) with the exposed 3´ end strand?

The enzyme DNA ligase is required continuously during DNA replication because

The X-ray crystallographs of the English chemist _______ were essential for the discovery of the structure of the DNA molecule.

Which of the following statements about mismatch repair of DNA is true?

The maestro of the replication fork is _______.

The _______ function of DNA polymerase reduces the number of mistakes by the square of the frequency of the error rate.

The structure of DNA is characterized by a

The rules formulated by Erwin Chargaff state that

The Hershey-Chase experiment persuaded most scientists that

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