Exam 39: Aerosol Drug Therapy

Which of the following aerosol drug delivery devices would you recommend against using with a toddler or small child? 1) Metered dose inhaler (MDI) 2) Small-volume jet nebulizer 3) Dry powder inhaler 4) MDI, holding chamber, and mask

Where do most aerosol particles in the 1- to 5-µm range deposit?

What is the retention of aerosol particles resulting from contact with the respiratory tract mucosa called?

Which of the following best describes a proper a dose-response assessment of a metered dose inhaler (MDI) bronchodilator?

Which of the following is a common method to measure aerosol particle size?

An asthmatic patient in severe distress with wheezing and dyspnea is admitted to the emergency department. After a conducting a full assessment and obtaining a pretreatment baseline, you start the patient on albuterol with a small-volume jet nebulizer. You should continue assessing and documenting all appropriate variables before and after each treatment until what point?

Each actuation of a typical metered dose inhaler delivers approximately what output volume?

To ensure delivery of the proper drug dosage with a metered dose inhaler, which of the following must be done before its use? 1) The canister valve stem should be cleaned with a pin. 2) The canister should be warmed to hand or body temperature. 3) The canister should be vigorously shaken.

What is the primary mechanism for central airway deposition of particles in the 1- to 5-µm range?

A physician orders continuous bronchodilator therapy with 1:200 albuterol for an asthmatic patient at the dosage of 20 mg/hr. How much 1:200 albuterol will be needed for the first hour of treatment?

Where do most aerosol particles that are less than 3 µm deposit?

Which of the following device-related factors have a major effect on pressurized metered dose inhaler (MDI) delivery of aerosolized drugs during mechanical ventilation? 1) MDI propellant formula 2) Type of spacer or adapter used 3) Position of spacer in circuit 4) Timing of MDI actuation

Which of the following factors affect pulmonary deposition of an aerosol? 1) Size of the particles 2) Shape and motion of the particles 3) Physical characteristics of the airways 4) Class of medication being delivered

Which of the following groups of patients are most likely to have difficulty using a simple metered dose inhaler for aerosol drug therapy? 1) Patients in acute distress 2) Infants and young children 3) Elderly persons

What measure is used to describe the variability of particle diameters in an aerosol?

A physician has ordered the antiviral agent ribavirin (Virazole) to be administered by aerosol to an infant with bronchiolitis. Which of the following devices would you recommend in this situation?

What is the major problem with using large volume nebulizers for continuous aerosol drug therapy?

What is the primary fate of inhaled aerosol particles that are between 1 and 0.5 µm?

Which of the following drugs or drug categories have been associated with increased airway resistance and bronchospasm during aerosol administration? 1) Steroids 2) Albuterol 3) Acetylcysteine 4) Antibiotics

A semiconscious patient with inadequate spontaneous ventilation requires aerosol drug administration. Which of the following approaches would you recommend?