Exam 39: Aerosol Drug Therapy

Which of the following patient skills are necessary to ensure effectiveness of drug administration via the aerosol route? 1) Ability to keep track of dosing requirements 2) Understanding of the methods and goals of therapy 3) Ability to recognize undesirable side effects

In addition to bedside pulmonary function test measures, what other components of patient assessment are useful in evaluating bronchodilator therapy? 1) Patient interview and observation 2) Measurement of vital signs 3) Chest auscultation 4) Arterial blood gas analysis and oximetry

Which term describes the primary mechanism for deposition of small particles?

During aerosol drug delivery using a small-volume jet nebulizer (SVN) set at 8 L/min input flow, a patient asks that the head of the bed be lowered to a semi-Fowler's position. Immediately after doing so, you observe a significant drop in SVN aerosol output, despite there being at least 3 ml of solution left in the reservoir. What would you do to correct this problem?

Which of the following is false about the optimal technique for using a small-volume jet nebulizer (SVN) for aerosol drug delivery?

Immediately after firing, the aerosol particles produced by most metered dose inhalers are approximately how large?

Which of the following ventilator-related factors have a major effect on metered dose inhaler delivery of aerosolized drugs during mechanical ventilation? 1) Mode of support 2) Presence of positive end expiratory pressure 3) V_T 4) Inspiratory wave form

Which of the following will increase aerosol deposition by inertial impaction? 1) High-velocity gas flow 2) Variable or irregular passages 3) Turbulent gas flow 4) Particles of high mass

Which of the following aerosols would have the highest rate of deposition by diffusion?

For which of the following patients would you recommend against using a flow-triggered metered dose inhaler (MDI) as the sole bronchodilator delivery system?

The key difference between a metered dose inhaler (MDI) holding chamber and a spacer is that the holding chamber incorporates which of the following?

What is the average amount of dead volume in a small-volume jet nebulizer after the device runs dry?

Which of the following devices would you select to deliver an aerosolized bronchodilator to a young child?

A physician wants to deliver a therapeutic aerosol to the lung parenchyma (alveolar region). To help ensure maximum deposition in this area, you would select an aerosol generator with an MMAD in what range?

You increase the fill volume from 2 to 4 ml in a small-volume jet nebulizer being used to administer a bronchodilator agent with an aerosol. What effect will this have on the amount of drug delivered?

After initially conducting a pre- and postbronchodilator assessment on a stable asthmatic patient admitted to the hospital, how often would you recommend reassessment of peak expiratory flow rate/forced expiratory volume in 1 second?

Which of the following circuit-related factors have a major effect on metered dose inhaler delivery of aerosolized drugs during mechanical ventilation? 1) Endotracheal tube size 2) Type of humidifier 3) Relative humidity 4) Temperature

When using a metered dose inhaler without a holding chamber or a spacer, the patient should be instructed to fire the device at what point?

What is the process by which aerosol suspension changes over time?

In mouth-breathing adult patients, which of the following factors is crucial in determining whether to use a mask or mouthpiece for aerosol drug delivery with a small-volume jet nebulizer?