Question 1

Elucidation of the histone code might

Accepted Answer

A) allow us to turn specific genes on or off. 
B) allow the determination of nucleosome composition. 
C) lead to chromatin remodeling. 
D) allow us to control translation. 
A) allow us to turn specific genes on or off. 
B) allow the determination of nucleosome composition. 
C) lead to chromatin remodeling. 
D) allow us to control translation.

Question 2

Although the specific mechanism of RNA interference has not been fully defined,it involves

Accepted Answer

A) double stranded RNA interference with mRNA. 
B) double stranded RNA interference with DNA. 
C) double stranded DNA interference with mRNA. 
D) double stranded mRNA interference with DNA. 
A) double stranded RNA interference with mRNA. 
B) double stranded RNA interference with DNA. 
C) double stranded DNA interference with mRNA. 
D) double stranded mRNA interference with DNA.

Question 3

The maintenance of a constant environment in a cell is called ___________.

Accepted Answer

A) active transport 
B) homeostasis 
C) gene expression 
D) translation 
A) active transport 
B) homeostasis 
C) gene expression 
D) translation

Question 4

If you were able to look very closely at a portion of DNA and find methylated histones,you would

Accepted Answer

A) be mistaken since only DNA can be methylated,not histones. 
B) be looking at a region of active chromatin. 
C) be looking at a region of inactive chromatin. 
D) be looking at a chromatin remodeling complex. 
A) be mistaken since only DNA can be methylated,not histones. 
B) be looking at a region of active chromatin. 
C) be looking at a region of inactive chromatin. 
D) be looking at a chromatin remodeling complex.

Question 5

Which of the following is not true about control of gene expression?

Accepted Answer

A) In bacteria it allows them to adopt to changing environments. 
B) In multicellular organisms it is critical for development. 
C) In bacteria it allows them to replicate without control. 
D) In multicellular organisms it allows them to maintain homeostasis. 
E) In multicellular organisms it allows them to function as a wholE. 
A) In bacteria it allows them to adopt to changing environments. 
B) In multicellular organisms it is critical for development. 
C) In bacteria it allows them to replicate without control. 
D) In multicellular organisms it allows them to maintain homeostasis. 
E) In multicellular organisms it allows them to function as a wholE.

Question 6

Which of the following statements regarding primary transcripts in eukaryotes is correct?

Accepted Answer

A) The primary transcript is composed of RNA polymerase and associated histones. 
B) The primary transcript has the exons removed and the introns retained for translation. 
C) The primary transcript is a faithful copy of the entire gene including exons and introns. 
D) The primary transcript is a faithful copy of the gene,but the introns have been removeD. 
E) The primary transcript is a faithful copy,but the exons have been removed. 
A) The primary transcript is composed of RNA polymerase and associated histones. 
B) The primary transcript has the exons removed and the introns retained for translation. 
C) The primary transcript is a faithful copy of the entire gene including exons and introns. 
D) The primary transcript is a faithful copy of the gene,but the introns have been removeD. 
E) The primary transcript is a faithful copy,but the exons have been removed.

Question 7

In gene regulation,negative control is exerted by a(n)

Accepted Answer

A) activator. 
B) operon. 
C) promoter. 
D) regulator. 
E) repressor. 
A) activator. 
B) operon. 
C) promoter. 
D) regulator. 
E) repressor.

Question 8

In __________ organisms,the primary function of a gene in a cell is to participate in regulating the body as a whole and not to responding to the cell's immediate environment.

Accepted Answer

A) multicellular 
B) diploid 
C) bacterial 
D) prokaryotic 
A) multicellular 
B) diploid 
C) bacterial 
D) prokaryotic

Question 9

Regulatory proteins can identify specific sequences on the DNA double helix without unwinding the helix.This is accomplished by

Accepted Answer

A) inserting DNA promoters into either the major groove or the minor groove of the double helix where the edges of the nitrogen bases protrude. 
B) inserting DNA-binding motifs into the minor groove of the double helix where the edges of the nitrogen bases protrude. 
C) inserting DNA polymerase into the major groove of the double helix where the edges of the nitrogen bases protrude. 
D) inserting RNA polymerase into the major groove of the double helix where the edges of the nitrogen bases protrude. 
E) inserting DNA-binding motifs into the major groove of the double helix where the edges of the nitrogen bases protrudE. 
A) inserting DNA promoters into either the major groove or the minor groove of the double helix where the edges of the nitrogen bases protrude. 
B) inserting DNA-binding motifs into the minor groove of the double helix where the edges of the nitrogen bases protrude. 
C) inserting DNA polymerase into the major groove of the double helix where the edges of the nitrogen bases protrude. 
D) inserting RNA polymerase into the major groove of the double helix where the edges of the nitrogen bases protrude. 
E) inserting DNA-binding motifs into the major groove of the double helix where the edges of the nitrogen bases protrudE.

Question 10

Proteins that bind to regulatory sequences have shapes that fit into the

Accepted Answer

A) promoter. 
B) operator. 
C) operon. 
D) minor groove of DNA. 
E) major groove of DNA. 
A) promoter. 
B) operator. 
C) operon. 
D) minor groove of DNA. 
E) major groove of DNA.

Question 11

The main form of glucose repression of the lac operon is

Accepted Answer

A) induction. 
B) repression. 
C) inducer exclusion. 
D) the CAP/cAMP system. 
A) induction. 
B) repression. 
C) inducer exclusion. 
D) the CAP/cAMP system.

Question 12

Transcriptional control-proteins increase the rate of transcription by binding to

Accepted Answer

A) mRNA sequences within the DNA. 
B) tRNA sequences within the DNA. 
C) operator sequences within the DNA. 
D) promotor sequences within the DNA. 
E) enhancer sequences within the DNA. 
A) mRNA sequences within the DNA. 
B) tRNA sequences within the DNA. 
C) operator sequences within the DNA. 
D) promotor sequences within the DNA. 
E) enhancer sequences within the DNA.

Question 13

All regulatory proteins have common DNA binding motifs,which are particular bends in their protein chains that permit them to interlock with the

Accepted Answer

A) minor groove of the DNA helix. 
B) major groove of the DNA helix. 
C) outside groove of the DNA helix. 
D) inside groove of the DNA helix. 
E) hydrogen bonding groove of the DNA helix. 
A) minor groove of the DNA helix. 
B) major groove of the DNA helix. 
C) outside groove of the DNA helix. 
D) inside groove of the DNA helix. 
E) hydrogen bonding groove of the DNA helix.

Question 14

Certain proteins can bind to specific DNA regulatory sequences by

Accepted Answer

A) entering the major groove of the DNA and reading the nucleotide base pairs. 
B) entering the minor groove of the DNA and reading the nucleotide base pairs. 
C) entering the major groove of RNA and reading the nucleotide base pairs. 
D) entering DNA's major groove by using DNA polymerase and reading the nucleotide base pairs. 
E) entering DNA's minor groove by using DNA polymerase and reading the nucleotide base pairs. 
A) entering the major groove of the DNA and reading the nucleotide base pairs. 
B) entering the minor groove of the DNA and reading the nucleotide base pairs. 
C) entering the major groove of RNA and reading the nucleotide base pairs. 
D) entering DNA's major groove by using DNA polymerase and reading the nucleotide base pairs. 
E) entering DNA's minor groove by using DNA polymerase and reading the nucleotide base pairs.

Question 15

Enhancers are the binding sites for the

Accepted Answer

A) promotors of DNA synthesis. 
B) suppressor factors. 
C) co-activation factors. 
D) mediator factors. 
E) specific transcription factors. 
A) promotors of DNA synthesis. 
B) suppressor factors. 
C) co-activation factors. 
D) mediator factors. 
E) specific transcription factors.

Question 16

Your research project involves the characterization of a recently identified transcription factor.As part of your project,you want to determine if this transcription factor binds directly to any of the general transcription factors.Unfortunately,however,you are having trouble expressing and purifying the full length protein.Which of the following options may help you achieve your research goal?

Accepted Answer

A) Since transcription domains cannot be separated,you will need to abandon this experiment and try a vastly different approach to your question. 
B) Express large amounts of the general transcription factors. 
C) Since transcription domains can be separated,try to express and purify only the DNA-binding domain. 
D) Since transcription domains can be separated,try to express and purify only the activation domain. 
A) Since transcription domains cannot be separated,you will need to abandon this experiment and try a vastly different approach to your question. 
B) Express large amounts of the general transcription factors. 
C) Since transcription domains can be separated,try to express and purify only the DNA-binding domain. 
D) Since transcription domains can be separated,try to express and purify only the activation domain.

Question 17

A protein that initiates the transcription of genes which allow the use of non-glucose molecules.

Accepted Answer

A) operon 
B) repressor 
C) promoter 
D) operator 
E) CAP 
A) operon 
B) repressor 
C) promoter 
D) operator 
E) CAP

Question 18

In eukaryotes,the binding of TFIID is followed by the binding of a number of other general transcription factors.Which of the following lists the correct order of binding of these factors?

Accepted Answer

A) TFIIA,TFIIB,TFIIE,TFIIF,TFIIH 
B) TFIIE,TFIIF,TFIIA,TFIIB,TFIIH 
C) TFIIF,TFIIH,TFIIB,TFIIE,TFIIA 
D) TFIIE,TFIIB,TFIIA,TFIIH,TFIIF 
A) TFIIA,TFIIB,TFIIE,TFIIF,TFIIH 
B) TFIIE,TFIIF,TFIIA,TFIIB,TFIIH 
C) TFIIF,TFIIH,TFIIB,TFIIE,TFIIA 
D) TFIIE,TFIIB,TFIIA,TFIIH,TFIIF

Question 19

The TFIID complex is formed by

Accepted Answer

A) TATA-binding protein TBP and TAFs. 
B) TATA-binding protein TBP,TAFs and RNA pol II. 
C) TAFs and the core promoter. 
D) TATA-binding protein and activators. 
A) TATA-binding protein TBP and TAFs. 
B) TATA-binding protein TBP,TAFs and RNA pol II. 
C) TAFs and the core promoter. 
D) TATA-binding protein and activators.

Question 20

Which of the following is the hallmark of multicellular organisms?

Accepted Answer

A) grow and divide rapidly 
B) cells adjust quickly to outside environment 
C) homeostasis 
D) quickly synthesize amount and type of enzymes according to available nutrients 
E) respond by gene action to oxygen availability 
A) grow and divide rapidly 
B) cells adjust quickly to outside environment 
C) homeostasis 
D) quickly synthesize amount and type of enzymes according to available nutrients 
E) respond by gene action to oxygen availability

Exam 16: Control of Gene Expression

Elucidation of the histone code might

Although the specific mechanism of RNA interference has not been fully defined,it involves

The maintenance of a constant environment in a cell is called ___________.

If you were able to look very closely at a portion of DNA and find methylated histones,you would

Which of the following is not true about control of gene expression?

Which of the following statements regarding primary transcripts in eukaryotes is correct?

In gene regulation,negative control is exerted by a(n)

In __________ organisms,the primary function of a gene in a cell is to participate in regulating the body as a whole and not to responding to the cell's immediate environment.

Regulatory proteins can identify specific sequences on the DNA double helix without unwinding the helix.This is accomplished by

Proteins that bind to regulatory sequences have shapes that fit into the

The main form of glucose repression of the lac operon is

Transcriptional control-proteins increase the rate of transcription by binding to

All regulatory proteins have common DNA binding motifs,which are particular bends in their protein chains that permit them to interlock with the

Certain proteins can bind to specific DNA regulatory sequences by

Enhancers are the binding sites for the

A protein that initiates the transcription of genes which allow the use of non-glucose molecules.

In eukaryotes,the binding of TFIID is followed by the binding of a number of other general transcription factors.Which of the following lists the correct order of binding of these factors?

The TFIID complex is formed by

Which of the following is the hallmark of multicellular organisms?

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