Question 1

Endonucleases and exonucleases are enzymes that can remove nucleotides.An endonuclease _______ while an exonuclease ______________.

Accepted Answer

A) chews away at the 5' end of DNA;cuts DNA internally 
B) chews away at a 3' end of DNA;cuts the 5' end of DNA 
C) cuts DNA internally;chews away at the end of DNA 
D) adds nucleotides internally to DNA;adds nucleotides on the 3' and 5' ends of DNA 
A) chews away at the 5' end of DNA;cuts DNA internally 
B) chews away at a 3' end of DNA;cuts the 5' end of DNA 
C) cuts DNA internally;chews away at the end of DNA 
D) adds nucleotides internally to DNA;adds nucleotides on the 3' and 5' ends of DNA C

Question 2

DNA consists of two antiparallel strands of nucleotide chains held together by

Accepted Answer

A) peptide bonds. 
B) polar covalent bonds. 
C) ionic bonds. 
D) hydrogen bonds. 
E) complementary base pairing bonds. 
A) peptide bonds. 
B) polar covalent bonds. 
C) ionic bonds. 
D) hydrogen bonds. 
E) complementary base pairing bonds. D

Question 3

Avery and his coworkers showed the "transforming principle" as

Accepted Answer

A) protein. 
B) polysaccharide. 
C) DNA. 
D) RNA. 
E) lipid. 
A) protein. 
B) polysaccharide. 
C) DNA. 
D) RNA. 
E) lipid. C

Question 4

When injected into a bacterial cell by T2 virus particles,the material that specifies the new generation of viruses is DNA and not protein.

Accepted Answer

A) Hershey and Chase 
B) Chargaff 
C) Franklin 
D) Watson and Crick 
A) Hershey and Chase 
B) Chargaff 
C) Franklin 
D) Watson and Crick

Question 5

DNA polymerase requires a(n)

Accepted Answer

A) amino acid primer. 
B) lipid primer. 
C) hydrophilic primer. 
D) DNA primer. 
E) RNA primer. 
A) amino acid primer. 
B) lipid primer. 
C) hydrophilic primer. 
D) DNA primer. 
E) RNA primer.

Question 6

The chemical bonds that stabilize the complimentary nitrogen bases into a double helix are

Accepted Answer

A) nitrogen bonds. 
B) hydrogen bonds. 
C) hydrophobic bonds. 
D) peptide bonds. 
E) phosphodiester bonds. 
A) nitrogen bonds. 
B) hydrogen bonds. 
C) hydrophobic bonds. 
D) peptide bonds. 
E) phosphodiester bonds.

Question 7

The enzyme that catalyzes the synthesis of new DNA molecules is called

Accepted Answer

A) DNA ligase. 
B) DNA polymerase. 
C) DNA gyrase. 
D) DNA helicase. 
E) DNA endonucleasE. 
A) DNA ligase. 
B) DNA polymerase. 
C) DNA gyrase. 
D) DNA helicase. 
E) DNA endonucleasE.

Question 8

Which of the following DNA replicating enzymes is responsible for unwinding the double helix of DNA?

Accepted Answer

A) DNA primase 
B) DNA polymerase I 
C) DNA helicase 
D) DNA gyrase 
E) DNA ligase 
A) DNA primase 
B) DNA polymerase I 
C) DNA helicase 
D) DNA gyrase 
E) DNA ligase

Question 9

When nonvirulent bacteria were mixed with dead virulent bacteria,Griffith unexpectedly found that the injected mice died.He explained this behavior by suggesting the nonvirulent strain of bacteria as being

Accepted Answer

A) activated. 
B) transformed. 
C) translated. 
D) transcribeD. 
E) expressed. 
A) activated. 
B) transformed. 
C) translated. 
D) transcribeD. 
E) expressed.

Question 10

The site of the opening of the DNA strands where active replication occurs is referred to as the

Accepted Answer

A) replication folk. 
B) replisome. 
C) primosome. 
D) DNA pol III complex of two enzymes. 
E) sliding clamp subunit. 
A) replication folk. 
B) replisome. 
C) primosome. 
D) DNA pol III complex of two enzymes. 
E) sliding clamp subunit.

Question 11

You are asked to participate in a clinical trial for a new drug that can activate telomerase.Which of the following is a likely risk of such a drug?

Accepted Answer

A) decreased capacity for tissue repair 
B) increased vulnerability to cancer 
C) premature aging 
D) decreased telomere length 
A) decreased capacity for tissue repair 
B) increased vulnerability to cancer 
C) premature aging 
D) decreased telomere length

Question 12

Which of the following is not a component of nucleic acids?

Accepted Answer

A) organic nitrogen bases 
B) sugar 
C) phosphate 
D) protein 
A) organic nitrogen bases 
B) sugar 
C) phosphate 
D) protein

Question 13

The two strands in the DNA molecule contain nitrogen bases which are

Accepted Answer

A) identical. 
B) parallel. 
C) complementary. 
D) the same in all species. 
E) exact copies of the protein they makE. 
A) identical. 
B) parallel. 
C) complementary. 
D) the same in all species. 
E) exact copies of the protein they makE.

Question 14

The replisome has two main subcomponents.They are

Accepted Answer

A) the replication folk and the sliding clamp subunit. 
B) the primosome and the sliding clamp subunit. 
C) the replication folk and the DNA pol III enzymes. 
D) the DNA pol III enzymes and the sliding clamp subunits. 
E) the primosome and a complex of two DNA pol III enzymes. 
A) the replication folk and the sliding clamp subunit. 
B) the primosome and the sliding clamp subunit. 
C) the replication folk and the DNA pol III enzymes. 
D) the DNA pol III enzymes and the sliding clamp subunits. 
E) the primosome and a complex of two DNA pol III enzymes.

Question 15

X-ray crystallography of purified DNA fibers shows a pattern that suggests a helical structure,and provides dimensions of that structure.

Accepted Answer

A) Hershey and Chase 
B) Chargaff 
C) Franklin 
D) Watson and Crick 
A) Hershey and Chase 
B) Chargaff 
C) Franklin 
D) Watson and Crick

Question 16

Avery,MacLeod,and McCarty's experiments revealed that the transforming principle had all of the following properties except

Accepted Answer

A) its activity was destroyed by treatment with proteases. 
B) its activity was unaffected by RNA-digesting enzymes. 
C) its activity was unaffected by lipid extraction. 
D) its activity was destroyed by treatment with DNA endonucleases. 
A) its activity was destroyed by treatment with proteases. 
B) its activity was unaffected by RNA-digesting enzymes. 
C) its activity was unaffected by lipid extraction. 
D) its activity was destroyed by treatment with DNA endonucleases.

Question 17

You are asked to give a classroom demonstration of DNA supercoiling.To do so,you take two different colored pieces of rubber tubing,twist them very tightly and excessively around each other and join the ends of the tubing appropriately.Next,you remove the supercoiling by breaking one strand and unwinding it.In this demonstration,the breaking and winding simulates the action of

Accepted Answer

A) exonucleases. 
B) polymerases. 
C) helicases. 
D) topoisomerases. 
A) exonucleases. 
B) polymerases. 
C) helicases. 
D) topoisomerases.

Question 18

In which of the following cells might you expect to find the highest level of telomerase?

Accepted Answer

A) muscle cells 
B) oocytes 
C) neurons 
D) cells that replenish the lining of the gut 
A) muscle cells 
B) oocytes 
C) neurons 
D) cells that replenish the lining of the gut

Question 19

The chemical bond connecting one nucleotide with the next one along the nucleic acid chain is called a

Accepted Answer

A) C = C bond. 
B) hydrogen bond. 
C) hydrophobic bond. 
D) phosphodiester bonD. 
E) peptide bond. 
A) C = C bond. 
B) hydrogen bond. 
C) hydrophobic bond. 
D) phosphodiester bonD. 
E) peptide bond.

Question 20

The lagging strand is replicated with stretches of Okazaki fragments and that is why its synthesis is considered to be

Accepted Answer

A) discontinuous. 
B) continuous. 
C) primed. 
D) never stopping. 
E) semiconservativE. 
A) discontinuous. 
B) continuous. 
C) primed. 
D) never stopping. 
E) semiconservativE.

Exam 14: Dna: the Genetic Material

Endonucleases and exonucleases are enzymes that can remove nucleotides.An endonuclease _______ while an exonuclease ______________.

DNA consists of two antiparallel strands of nucleotide chains held together by

Avery and his coworkers showed the "transforming principle" as

When injected into a bacterial cell by T2 virus particles,the material that specifies the new generation of viruses is DNA and not protein.

DNA polymerase requires a(n)

The chemical bonds that stabilize the complimentary nitrogen bases into a double helix are

The enzyme that catalyzes the synthesis of new DNA molecules is called

Which of the following DNA replicating enzymes is responsible for unwinding the double helix of DNA?

When nonvirulent bacteria were mixed with dead virulent bacteria,Griffith unexpectedly found that the injected mice died.He explained this behavior by suggesting the nonvirulent strain of bacteria as being

The site of the opening of the DNA strands where active replication occurs is referred to as the

You are asked to participate in a clinical trial for a new drug that can activate telomerase.Which of the following is a likely risk of such a drug?

Which of the following is not a component of nucleic acids?

The two strands in the DNA molecule contain nitrogen bases which are

The replisome has two main subcomponents.They are

X-ray crystallography of purified DNA fibers shows a pattern that suggests a helical structure,and provides dimensions of that structure.

Avery,MacLeod,and McCarty's experiments revealed that the transforming principle had all of the following properties except

In which of the following cells might you expect to find the highest level of telomerase?

The chemical bond connecting one nucleotide with the next one along the nucleic acid chain is called a

The lagging strand is replicated with stretches of Okazaki fragments and that is why its synthesis is considered to be

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Endonucleases and exonucleases are enzymes that can remove nucleotides.An endonuclease _ while an exonuclease ________.