Question 1

The majority (45%)of the human genome is composed of

Accepted Answer

A) introns. 
B) exons. 
C) templates. 
D) transposons. 
E) pseudogenes. 
A) introns. 
B) exons. 
C) templates. 
D) transposons. 
E) pseudogenes. D

Question 2

Rice and its grain relatives,maize,barley,and wheat,diverged from a common ancestor 50 million years ago,however the chromosomes of these plants demonstrate extensive conserved arrangements of segments.This phenomenon is called

Accepted Answer

A) a linkage disequilibrium. 
B) a single nucleotide polymorphisms. 
C) a contig. 
D) synteny. 
E) expressed sequence equilibrium. 
A) a linkage disequilibrium. 
B) a single nucleotide polymorphisms. 
C) a contig. 
D) synteny. 
E) expressed sequence equilibrium. D

Question 3

The sequencing method that cuts DNA segments into fragments,arranges those fragments based on overlapping nucleotide sequences,and then clones these fragments is called

Accepted Answer

A) shotgun sequencing. 
B) clone by clone sequencing. 
C) RFLP sequencing. 
D) consensus sequencing. 
A) shotgun sequencing. 
B) clone by clone sequencing. 
C) RFLP sequencing. 
D) consensus sequencing. B

Question 4

Microarrays are created by

Accepted Answer

A) robotically placing DNA on to a microscope slide and probing with RNA from the tissue of interest. 
B) robotically placing DNA on to a microscope slide and probing with another DNA from the tissue of interest. 
C) robotically placing DNA on to a microscope slide and probing with SNPs from the tissue of interest. 
D) robotically placing DNA on to a microscope slide and probing with STSs from the tissue of interest. 
E) clone by clone sequencing. 
A) robotically placing DNA on to a microscope slide and probing with RNA from the tissue of interest. 
B) robotically placing DNA on to a microscope slide and probing with another DNA from the tissue of interest. 
C) robotically placing DNA on to a microscope slide and probing with SNPs from the tissue of interest. 
D) robotically placing DNA on to a microscope slide and probing with STSs from the tissue of interest. 
E) clone by clone sequencing.

Question 5

______ maps are generated using actual landmarks within DNA sequences.

Accepted Answer

A) Genetic 
B) DNA 
C) Physical 
D) Chromosomal 
A) Genetic 
B) DNA 
C) Physical 
D) Chromosomal

Question 6

The sequencing method that cuts the DNA of an entire chromosome into small fragments and then clones these fragments is called

Accepted Answer

A) shotgun sequencing. 
B) clone by clone sequencing. 
C) RFLP sequencing. 
D) consensus sequencing. 
A) shotgun sequencing. 
B) clone by clone sequencing. 
C) RFLP sequencing. 
D) consensus sequencing.

Question 7

Your research project involves the characterization of a novel protein.To learn more about its function you perform a yeast two-hybrid screen to identify potential interacting proteins.In your first screening attempt,you isolate one clone.You send the clone to be sequenced at the local sequencing facility.After translating the sequencing data,what should you do to (i)find out what type of protein this clone encodes,and (ii)get an idea about its possible function?

Accepted Answer

A) Run a blast search. 
B) Identify the intron/exon organization. 
C) Localize the gene to a specific chromosomal region. 
D) Search the human genome sequence for your clone. 
A) Run a blast search. 
B) Identify the intron/exon organization. 
C) Localize the gene to a specific chromosomal region. 
D) Search the human genome sequence for your clone.

Question 8

Long interspersed elements (LINES)are a type of

Accepted Answer

A) pseudogene. 
B) proteone. 
C) exon. 
D) intron. 
E) transposon. 
A) pseudogene. 
B) proteone. 
C) exon. 
D) intron. 
E) transposon.

Question 9

A _____ consists of all of the DNA in a nucleus of a cell.

Accepted Answer

A) genome 
B) chromosome 
C) gene 
D) protein 
A) genome 
B) chromosome 
C) gene 
D) protein

Question 10

Chloroplasts can replicate independently because

Accepted Answer

A) of synteny. 
B) it has its own genome. 
C) of its repetitive DNA sequences. 
D) of its ability to use restriction enzymes. 
E) it has several contigs. 
A) of synteny. 
B) it has its own genome. 
C) of its repetitive DNA sequences. 
D) of its ability to use restriction enzymes. 
E) it has several contigs.

Question 11

______ maps show the relative location of genes on a chromosome as determined by recombination frequencies.

Accepted Answer

A) DNA 
B) Genetic 
C) Chromosomal 
D) Physical 
A) DNA 
B) Genetic 
C) Chromosomal 
D) Physical

Question 12

Linkage disequilibrium is

Accepted Answer

A) the tendency of genes to be totally randomized during meiosis. 
B) the tendency of genes not to be randomized during meiosis. 
C) the tendency of genes of single nucleotides polymorphisms to be rearranged during meiosis because of crossing over. 
D) the tendency of genes to link together within certain blocks along the chromosome. 
E) the tendency of contigs being so randomized that mapping becomes an issue for gene sequencing. 
A) the tendency of genes to be totally randomized during meiosis. 
B) the tendency of genes not to be randomized during meiosis. 
C) the tendency of genes of single nucleotides polymorphisms to be rearranged during meiosis because of crossing over. 
D) the tendency of genes to link together within certain blocks along the chromosome. 
E) the tendency of contigs being so randomized that mapping becomes an issue for gene sequencing.

Question 13

Distances on a genetic map are measured in _____ units.

Accepted Answer

A) centromere 
B) DNA 
C) dalton 
D) centimorgan 
A) centromere 
B) DNA 
C) dalton 
D) centimorgan

Question 14

Which of the following techniques can be used to detect chromosomal abnormalities?

Accepted Answer

A) EST 
B) FISH 
C) STS 
D) SNP 
A) EST 
B) FISH 
C) STS 
D) SNP

Question 15

Groups of related,but distinctly different,genes that appear to have arisen from a single ancestral gene are referred to as

Accepted Answer

A) segmental duplications. 
B) pseudogenes. 
C) tandem clusters. 
D) multigene families. 
E) expressed sequences. 
A) segmental duplications. 
B) pseudogenes. 
C) tandem clusters. 
D) multigene families. 
E) expressed sequences.

Question 16

The majority of DNA in a human is

Accepted Answer

A) composed of short interspersed elements. 
B) non-coding. 
C) simple sequence repeats. 
D) segmental duplications. 
E) structural. 
A) composed of short interspersed elements. 
B) non-coding. 
C) simple sequence repeats. 
D) segmental duplications. 
E) structural.

Question 17

A human gene is composed of numerous fragments of protein-encoding information known as ______.

Accepted Answer

A) DNA 
B) mRNA 
C) exons 
D) introns 
A) DNA 
B) mRNA 
C) exons 
D) introns

Question 18

A genome sequence with minimal gaps,with the sequences in the correct order,and having no more that 1% error in 10,000 nucleotides would be considered a

Accepted Answer

A) PCR sequence. 
B) draft sequence. 
C) finished sequence. 
D) shotgun sequence. 
E) clone by clone sequencE. 
A) PCR sequence. 
B) draft sequence. 
C) finished sequence. 
D) shotgun sequence. 
E) clone by clone sequencE.

Question 19

How is the study of genomics expected to influence future health care?

Accepted Answer

A) The study of genomics is expected to provide insight into the relationship between genes and the environment,and why certain people get sick while others remain healthy.It should enable us to learn more about the causes and effects of various diseases,illnesses,and infections.Such information will help us to identify ways to improve health care and prevent disease. 
B) The study of genomics will allow us to treat,with the use of genetic engineering,various diseases of genetic origin.It is just a matter of time before we are able to treat all diseases of genetic origin with this technique. 
C) The study of genomics will allow us to use bacteria and viruses to create vaccinations for virually all diseases of genetic origin. 
A) The study of genomics is expected to provide insight into the relationship between genes and the environment,and why certain people get sick while others remain healthy.It should enable us to learn more about the causes and effects of various diseases,illnesses,and infections.Such information will help us to identify ways to improve health care and prevent disease. 
B) The study of genomics will allow us to treat,with the use of genetic engineering,various diseases of genetic origin.It is just a matter of time before we are able to treat all diseases of genetic origin with this technique. 
C) The study of genomics will allow us to use bacteria and viruses to create vaccinations for virually all diseases of genetic origin.

Question 20

Which of the following organisms has the largest genome?

Accepted Answer

A) rice 
B) human 
C) fruit fly 
D) yeast 
A) rice 
B) human 
C) fruit fly 
D) yeast

Exam 18: Genomics

The majority (45%)of the human genome is composed of

Rice and its grain relatives,maize,barley,and wheat,diverged from a common ancestor 50 million years ago,however the chromosomes of these plants demonstrate extensive conserved arrangements of segments.This phenomenon is called

The sequencing method that cuts DNA segments into fragments,arranges those fragments based on overlapping nucleotide sequences,and then clones these fragments is called

Microarrays are created by

______ maps are generated using actual landmarks within DNA sequences.

The sequencing method that cuts the DNA of an entire chromosome into small fragments and then clones these fragments is called

Long interspersed elements (LINES)are a type of

A _____ consists of all of the DNA in a nucleus of a cell.

Chloroplasts can replicate independently because

______ maps show the relative location of genes on a chromosome as determined by recombination frequencies.

Linkage disequilibrium is

Distances on a genetic map are measured in _____ units.

Which of the following techniques can be used to detect chromosomal abnormalities?

Groups of related,but distinctly different,genes that appear to have arisen from a single ancestral gene are referred to as

The majority of DNA in a human is

A human gene is composed of numerous fragments of protein-encoding information known as ______.

A genome sequence with minimal gaps,with the sequences in the correct order,and having no more that 1% error in 10,000 nucleotides would be considered a

How is the study of genomics expected to influence future health care?

Which of the following organisms has the largest genome?

The Science of Biology

The Nature of Molecules

The Chemical Building Blocks of Life

Cell Structure

Membranes

Energy and Metabolism

How Cells Harvest Energy

Photosynthesis

Cell Communication

How Cells Divide

Sexual Reproduction and Meiosis

Patterns of Inheritance

Chromosomes Mapping and the Meiosis - Inheritance Connection

Dna: the Genetic Material

Genes and How They Work

Control of Gene Expression

Biotechnology

Cellular Mechanisms of Development

Genes Within Populations

The Evidence for Evolution

The Origin of Species

Systematics and the Phylogenetic Revolution

Genome Evolution

Evolution of Development

The Tree of Life

Viruses

Prokaryotes

Protists

Overview of Green Plants

Fungi

Overview of Animal Diversity

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Coelomate Invertebrates

Vertebrates

Plant Form

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Transport in Plants

Plant Nutrition and Soils

Plant Defense Responses

Sensory Systems in Plants

Plant Reproduction

The Animal Body and Principles of Regulation

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