Exam 14: Dna and the Gene: Synthesis and Repair

Put the following steps of DNA replication in chronological order. 1)Single-stranded binding proteins attach to DNA strands. 2)Hydrogen bonds between base pairs of antiparallel strands are broken. 3)Primase binds to the site of origin. 4)DNA polymerase binds to the template strand. 5)An RNA primer is created.

The bacterial transduction experiments done by Hershey and Chase,and the bacterial transformation experiments done by Griffith,supported the same conclusion,which was _____.

What provides the energy for the polymerization reactions in DNA synthesis?

Hershey and Chase set out to determine what molecule served as the unit of inheritance.They completed a series of transduction experiments in which E.coli was infected by a T2 virus.Which molecular component of the T2 virus actually ended up inside the cell?

What can you infer from the information presented in this table?

Which of the following agents are unlikely to cause mutations in DNA?

Recent studies have shown that xeroderma pigmentosum (an error in the nucleotide excision repair process)can result from mutations in one of seven genes.What can you infer from this finding?

Researchers found E.coli that had mutation rates 100 times higher than normal.What is a possible explanation for these results?

Bodnar et al (1998)used telomerase to extend the life span of normal human cells.Telomere shortening puts a limit on the number of times a cell can divide.How might adding telomerase affect cellular aging?

In the polymerization of DNA,a phosphodiester bond is formed between a phosphate group of the nucleotide being added and _____ of the last nucleotide in the polymer.

Figure 14.3 -Refer to Figure 14.3.Which structure is responsible for stabilizing DNA in its single-stranded form?

What is a telomere?

If DNA repair mechanisms fail,which of the following is not a direct result?

The fact that within a double-stranded DNA molecule,adenine forms two hydrogen bonds with thymine and cytosine forms three hydrogen bonds allows _____.

What are pyrimidine dimers?

How does the simple primary and secondary structure of DNA hold the information needed to code for the many features of multicellular organisms?

In humans,xeroderma pigmentosum is a disorder of the nucleotide excision repair mechanism.These individuals are unable to repair DNA damage caused by ultraviolet light.Which of the following are the most prominent types of mutations in individuals suffering from xeroderma pigmentosum?