Exam 15: How Genes Work

Figure 15.4. -Refer to Figure 15.4.Homocystinuria is a genetic disorder that results from a defect in one of the enzymes of the metabolic pathway shown.The gene for which enzyme/molecule is most likely defective?

What does it mean when we say the genetic code is redundant?

What molecule serves as a link between the information-containing macromolecule,DNA,and protein synthesis?

Figure 15.2 -Refer to Figure 15.2.A branched metabolic pathway synthesizes two related amino acids (D and F).If there is a genetic defect,resulting in a nonfunctional enzyme (3),how could you ensure that adequate amounts of the amino acid F are synthesized?

-Given the DNA template shown above,which of the following bases would you find in a complementary RNA strand and where would they be synthesized?

Once researchers identified DNA as the unit of inheritance,they asked how information was transferred from the DNA in the nucleus to the site of protein synthesis in the cytoplasm.What is the mechanism of information transfer?

Beadle discovered that metabolic pathways are studied most effectively using which of the following techniques?

The proteome is all the proteins produced by an organism.The genome is the totality of all genes of an organism.If the proteome is much larger than the genome,which of the following statements would be accurate?

There are three stop codons (nonsense codons);all remaining codons specify addition of an amino acid (sense codons).How many sense codons are there?

The HIV virus that causes AIDS is an RNA virus.What is an RNA virus?

Knockout mice have been genetically altered to knock out specific genes.How are these mice most often used in research?

The statement,DNA → RNA → Proteins,_____.

In the Morse code,a series of dots and dashes code for letters of the alphabet.How is this analogous to the genetic code?

The original DNA has the base sequence AGCGTTACCGT;a mutation in the DNA strand results in the base sequence AGGCGTTACCGT.What does this tell you about the mutation?

Which of the following molecules is not required for translation?

According to the central dogma,what molecule should go in the blank? DNA → _____ → Proteins

Genotype is to _____ as phenotype is to _____.

Codons,the three base sequences that code for specific amino acids,are part of _____.

Which of the following is not synthesized from a DNA template?

-According to the table and figure above,which enzyme is defective in the strain with the arg2 mutation?