Exam 6: Lipids, membranes, and the First Cells

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How do phospholipids interact with water molecules?

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You have just discovered an organism that lives in extremely cold environments.Which of the following would you predict to be true about the phospholipids in its membranes,compared to phospholipids in the membranes of organisms that live in warmer environments?

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To determine if membrane proteins affect membrane permeability,you could isolate the proteins from the lipid components of the membrane by using detergents.Then you could separate the individual proteins and test each of them in a planar bilayer.What technique could you use to separate the proteins from one another after they have been isolated from the membrane?

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Which of the following is the best explanation for why vegetable oil is a liquid at room temperature while animal fats are solid?

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In an experiment involving planar bilayers,a solution of table salt (sodium and chloride ions in water)is added on the left side of the membrane while pure water is added on the right side.After 30 minutes the researchers test for the presence of ions on each side of the membrane.The right side tests negative for ions.What can you conclude?

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Steroid hormones are large communication molecules that are modified cholesterol molecules.How do you think they enter a cell?

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Valine,a nonpolar amino acid,shows up in the wrong place in the hemoglobin of sickle-cell anemia,causing the disease.This is due to a genetic mutation.The result of this mutation is that hemoglobin molecules-which transport oxygen in red blood cells-stick together,causing the red blood cells to become distorted,but without having any significant effect on oxygen binding.Based on what you know about protein structure and the polarity of amino acids,predict where the mutated valine would most likely be found.

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