Exam 35: Thrombophilia

A patient being treated with heparin therapy has a 65% decrease in platelet count from the baseline count after 6 days of being on the anticoagulant.What is the probable cause of the decrease?

Which of the following inherited condition is considered a low risk for a venous thromboembolic event?

Patients with protein C and/or S deficiencies are at risk for which type of complication?

Why are clotting and molecular assays both needed for a diagnosis of APCR?

Antithrombin and heparin cofactor II primarily inhibit which of the following factors?

How does the INR standardize the prothrombin time?

Antibodies to which component(s)are thought to complex with the phospholipids resulting in antiphospholipid antibody syndrome are:

A 30-year-old patient is diagnosed with a third episode of DVT.He is currently hospitalized and receiving heparin therapy.The physician orders a thrombotic risk battery of tests.What is the most appropriate action that the laboratory professional should take?

It has been determined that a patient has activated protein C resistance.Name the most prevalent genetic mutation associated with this finding.

The reason that thrombolytic agents are not recommended for prolonged anticoagulation therapy is that they:

Which of the following best describes the most common cause of hyperhomocysteinemia?

A tendency to favor thrombus formation produced from an imbalance in the major constituents of the hemostatic system is defined as:

A patient with thrombophilia has a decreased functional and antigenic activity of protein C.What is the diagnosis?

Failure of protein C to destroy FVa and FVIIIa results in an increase in what hemostatic system alteration?