Exam 12: Anemias of Disordered Iron Metabolism and Heme Synthesis

Name the molecule that is responsible for oxidizing ferrous iron to ferric iron to be combined with transferrin.

What is the typical PB picture in a patient with stage 1 IDA?

Hypochromic,microcytic anemia is found in which stage of iron deficiency?

What measurements are used in the percent saturation calculation?

Use this case to answer the following questions: Hugo brought his 2-year-old son to the doctor for a checkup.He had recently moved to upstate New York from a poor neighborhood in Los Angeles.Hugo commented that his son had been very cranky lately.He attributed this condition to teething.He had a habit of chewing on his favorite painted wooden toys,which were family heirlooms.The well-baby clinic referred Hugo's son to the hospital laboratory because he was lethargic and pale.A CBC was ordered. -What is the most probable diagnosis based on these clinical findings and patient history?

Which laboratory test measures the maximum amount of iron able to be bound to transferrin in the serum?

Iron-deficiency anemia can occur from what three mechanisms?

A defect in the HFE gene would cause which of the following to occur?

A storage form of iron is:

Regulation of iron entering the body occurs mainly through which mechanism?

Anemia of chronic disease is characterized by:

Which laboratory test would be most helpful in differentiating iron-deficiency anemia from anemia of chronic disease?

Use this case to answer the following questions: Hugo brought his 2-year-old son to the doctor for a checkup.He had recently moved to upstate New York from a poor neighborhood in Los Angeles.Hugo commented that his son had been very cranky lately.He attributed this condition to teething.He had a habit of chewing on his favorite painted wooden toys,which were family heirlooms.The well-baby clinic referred Hugo's son to the hospital laboratory because he was lethargic and pale.A CBC was ordered. -What reflex laboratory tests would be helpful to identify the cause of this anemia?

Note the text states 200 mcg/L in premenopausal females and 300 µg/L in men and postmenopausal women (page 220).Iron overload exists when ferritin levels are higher than:

Erythropoietic porphyrias are associated with:

Which of the following is the correct progression of iron-deficiency anemia?

Explain the absorption and assimilation of nonheme iron into hemoglobin in the RBC.

Use this case to answer the following questions: Hugo brought his 2-year-old son to the doctor for a checkup.He had recently moved to upstate New York from a poor neighborhood in Los Angeles.Hugo commented that his son had been very cranky lately.He attributed this condition to teething.He had a habit of chewing on his favorite painted wooden toys,which were family heirlooms.The well-baby clinic referred Hugo's son to the hospital laboratory because he was lethargic and pale.A CBC was ordered. -The patient was found to have normal serum iron studies.What other reflex test(s)should be done?

What organ is the primary storage depot for iron?

How is sideroblastic anemia confirmed by laboratory analysis? Explain your answer.