Exam 2: Cellular Homeostasis

Cdks must be complexed with what molecule to drive one cell to the next cell-cycle stage?

Predict the effect of p16 on the cell cycle of dividing cells.

To be considered a true polymorphism, a SNP must occur with a frequency of:

In which phase of the cell cycle is a cell quiescent?

Which two proteins are critical for the effective function of the G1 checkpoint?

Disposal of damaged or misfolded proteins is carried out by which cell component?

List the four major phospholipids found in the plasma membrane of hematopoietic cells and explain their unique distribution.

Which of the following influence the stability of the mRNA and the efficiency of translation?

The plasma membrane of blood cells is characterized by which of the following?

In which phase of mitosis do the chromosomes align on opposite poles of the cell?

Initiation of apoptosis occurs primarily with:

Predict the effect that the Bax:Bcl-2 complex will have on the apoptotic pathway.

If an organism fails to regulate apoptosis, resulting in excessive apoptosis, which of the following processes might result?

The point in the cell cycle after which cell division is complete but before the next round of DNA synthesis is:

Which phospholipids are predominantly found in the inner layer of the lipid bilayer?

What feature distinguishes necrosis from apoptosis?

Explain the role of epigenetic alterations in cancer development.

Malignancies can result from which of the following?

What protein is responsible for both pro-apoptotic and anti-apoptotic regulation?

The (R) restriction point occurs during what phase in the cell cycle?