A benign condition has the following characteristics: WBC count of 45 × 109/L with a left shift and normal RBC count. What is this condition?

A) Leukoerythroblastosis B) Pelger-Huët anomaly C) Leukemoid reaction D) Pyknosis A) Leukoerythroblastosis B) Pelger-Huët anomaly C) Leukemoid reaction D) Pyknosis

Exam 21: Nonmalignant Disorders of Leukocytes: Granulocytes and Monocytes

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A healthy individual has his blood drawn as a part of a routine physical. The laboratician performing the differential notes a neutrophil with a nucleus that appears dumbbell shaped. After scanning the entire slide, it appears that the vast majority of neutrophils have the same, bi-lobed nuclei with highly clumped nuclear chromatin. All other leukocytes appear normal. The conclusion from this is that the patient has:

(Multiple Choice)

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Question 21

A patient has a fever and a WBC of 25 × 10⁹/L with bands and metamyelocytes present. Which of the following conditions describes these results?

(Multiple Choice)

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Question 22

A 78-year-old female receiving chemotherapy for breast cancer had a CBC performed after her last treatment. Her absolute neutrophil count was 1.0 × 10⁹/L. What information can be concluded from this?

(Multiple Choice)

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Question 23

A benign condition has the following characteristics: WBC count of 45 × 10⁹/L with a left shift and normal RBC count. What is this condition?

(Multiple Choice)

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Question 24

In the identification of Pelger-Huët cells, what nuclear characteristic other than the dumbbell shape aids in differentiating these cells from bands?

(Multiple Choice)

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Question 25

A patient presents with splenomegaly and bone pain. Laboratory findings reveal large macrophages with small eccentric nuclei and cytoplasm with a wrinkled appearance. Further testing shows leukopenia, thrombocytopenia, and anemia. What is the probable cause?

(Multiple Choice)

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Question 26

Which of the following anomalies is morphologically similar to toxic granulation and is often seen in patients who have poor mucopolysaccharide degradation?

(Multiple Choice)

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Question 27

A patient's smear shows clumping of neutrophils. The absolute neutrophil count shows a neutropenia. What can be done to obtain a reliable neutrophil count?

(Multiple Choice)

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Question 28

A neutrophil contains many giant gray-green peroxidase-positive bodies and giant lysosomes. Which of the following anomalies is associated with these findings?

(Multiple Choice)

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Question 29

The processing of a sample in a lavender top tube received in the lab at 10 a.m. is delayed because of a sudden fire drill. The sample is processed and analyzed at 2 p.m. Significant findings on this patient include an absolute neutrophil count of 1.5 × 10⁹/L. What can be concluded from this?

(Multiple Choice)

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Question 30

Which of the following can result in basophilia?

(Multiple Choice)

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Question 31

A patient presents with splenomegaly and bone pain. Laboratory findings reveal large macrophages with small eccentric nuclei and cytoplasm with a wrinkled appearance. Further testing shows leukopenia, thrombocytopenia, and anemia. How can the diagnosis be confirmed?

(Multiple Choice)

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Question 32

A neutrophilia that results from a redistribution of neutrophils from the marginating pool into the circulating pool is called:

(Multiple Choice)

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Question 33

Which of the following diseases is characterized by a defect in sphingomyelinase, which results in macrophages with a foamy appearance?

(Multiple Choice)

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Question 34

What disease state correlates highly with the presence of cytoplasmic vacuoles in freshly drawn blood?

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Question 35

How does immediate neutrophilia differ from acute neutrophilia?

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Question 36

Showing 21 - 36 of 36

Exam 21: Nonmalignant Disorders of Leukocytes: Granulocytes and Monocytes

A patient has a fever and a WBC of 25 × 109/L with bands and metamyelocytes present. Which of the following conditions describes these results?

A 78-year-old female receiving chemotherapy for breast cancer had a CBC performed after her last treatment. Her absolute neutrophil count was 1.0 × 109/L. What information can be concluded from this?

A benign condition has the following characteristics: WBC count of 45 × 109/L with a left shift and normal RBC count. What is this condition?

In the identification of Pelger-Huët cells, what nuclear characteristic other than the dumbbell shape aids in differentiating these cells from bands?

A patient presents with splenomegaly and bone pain. Laboratory findings reveal large macrophages with small eccentric nuclei and cytoplasm with a wrinkled appearance. Further testing shows leukopenia, thrombocytopenia, and anemia. What is the probable cause?

Which of the following anomalies is morphologically similar to toxic granulation and is often seen in patients who have poor mucopolysaccharide degradation?

A patient's smear shows clumping of neutrophils. The absolute neutrophil count shows a neutropenia. What can be done to obtain a reliable neutrophil count?

A neutrophil contains many giant gray-green peroxidase-positive bodies and giant lysosomes. Which of the following anomalies is associated with these findings?

The processing of a sample in a lavender top tube received in the lab at 10 a.m. is delayed because of a sudden fire drill. The sample is processed and analyzed at 2 p.m. Significant findings on this patient include an absolute neutrophil count of 1.5 × 109/L. What can be concluded from this?

Which of the following can result in basophilia?

A patient presents with splenomegaly and bone pain. Laboratory findings reveal large macrophages with small eccentric nuclei and cytoplasm with a wrinkled appearance. Further testing shows leukopenia, thrombocytopenia, and anemia. How can the diagnosis be confirmed?

A neutrophilia that results from a redistribution of neutrophils from the marginating pool into the circulating pool is called:

Which of the following diseases is characterized by a defect in sphingomyelinase, which results in macrophages with a foamy appearance?

What disease state correlates highly with the presence of cytoplasmic vacuoles in freshly drawn blood?

How does immediate neutrophilia differ from acute neutrophilia?

Introduction

Cellular Homeostasis

Structure and Function of Hematopoietic Organs

Hematopoiesis

The Erythrocyte

Hemoglobin

Granulocytes and Monocytes

Lymphocytes

The Platelet

The Complete Blood Count and Peripheral Blood Smear Evaluation

Introduction to Anemia

Anemias of Disordered Iron Metabolism and Heme Synthesis

Hemoglobinopathies: Qualitative Defects

Thalassemia

Megaloblastic and Nonmegaloblastic Macrocytic Anemias

Hypoproliferative Anemias

Hemolytic Anemia: Membrane Defects

Hemolytic Anemia: Enzyme Deficiencies

Hemolytic Anemia: Immune Anemias

Hemolytic Anemia: Nonimmune Defects

Nonmalignant Lymphocyte Disorders

Introduction to Hematopoietic Neoplasms

Myeloproliferative Neoplasms

Myelodysplastic Syndromes

Acute Myeloid Leukemias

Precursor Lymphoid Neoplasms

Mature Lymphoid Neoplasms

Hematopoietic Stem Cell Transplantation

Morphologic Analysis of Body Fluids in the Hematology

Primary Hemostasis

Secondary Hemostasis and Fibrinolysis

Disorders of Primary Hemostasis

Disorders of Secondary Hemostasis

Thrombophilia

Hemostasis: Laboratory Testing and Instrumentation

Hematology Procedures

Bone Marrow Examination

Automation in Hematology

Flow Cytometry

Chromosome Analysis of Hematopoietic and Lymphoid Disorders

Molecular Analysis of Hematologic Diseases

Quality Assessment in the Hematology Laboratory

Filters

A patient has a fever and a WBC of 25 × 10⁹/L with bands and metamyelocytes present. Which of the following conditions describes these results?

A 78-year-old female receiving chemotherapy for breast cancer had a CBC performed after her last treatment. Her absolute neutrophil count was 1.0 × 10⁹/L. What information can be concluded from this?

A benign condition has the following characteristics: WBC count of 45 × 10⁹/L with a left shift and normal RBC count. What is this condition?

The processing of a sample in a lavender top tube received in the lab at 10 a.m. is delayed because of a sudden fire drill. The sample is processed and analyzed at 2 p.m. Significant findings on this patient include an absolute neutrophil count of 1.5 × 10⁹/L. What can be concluded from this?