Question 1

Sequential activation of plasma procoagulant proteins that induce the formation of insoluble blood proteins occurs in which phase of coagulation?

Accepted Answer

A)  Formation of primary platelet plug 
B)  Formation of secondary hemostatic plug 
C)  Fibrinolysis of existing hemostatic plugs 
D)  Inhibition of primary and secondary hemostatic plug formation 
A)  Formation of primary platelet plug 
B)  Formation of secondary hemostatic plug 
C)  Fibrinolysis of existing hemostatic plugs 
D)  Inhibition of primary and secondary hemostatic plug formation

Question 2

Which of the following is a role of platelets in secondary hemostasis?

Accepted Answer

A)  To secrete factors needed for serine protease activation 
B)  To initiate cross-linking of the fibrin monomers 
C)  To activate thrombin 
D)  To initiate contact activation 
A)  To secrete factors needed for serine protease activation 
B)  To initiate cross-linking of the fibrin monomers 
C)  To activate thrombin 
D)  To initiate contact activation

Question 3

Correlate blood vessel histology to vessel type and function in hemostasis.

Accepted Answer

Tunica adventitia: thick outer layer of

Question 4

After a blood vessel injury, which of the following initiates hemostasis?

Accepted Answer

A)  Endothelial communication 
B)  Platelet function inhibition 
C)  Vasoconstriction 
D)  Vasodilation 
A)  Endothelial communication 
B)  Platelet function inhibition 
C)  Vasoconstriction 
D)  Vasodilation

Question 5

Which of the following acts as a transport portal for granules to move from the organelle zone to the membrane zone?

Accepted Answer

A)  Open canalicular system 
B)  Dense tubular system 
C)  Membrane glycoproteins 
D)  Endoplasmic reticulum 
A)  Open canalicular system 
B)  Dense tubular system 
C)  Membrane glycoproteins 
D)  Endoplasmic reticulum

Question 6

Which of the following substances endogenous to the dense bodies is responsible for continuous platelet activation of surrounding platelets?

Accepted Answer

A)  Platelet factor 4 
B)  Collagen 
C)  ADP 
D)  Epinephrine 
A)  Platelet factor 4 
B)  Collagen 
C)  ADP 
D)  Epinephrine

Question 7

Which of the following is responsible for the platelet surface negative charge and is found on the surface membrane of the interior channels?

Accepted Answer

A)  Dense tubular system 
B)  Open canalicular system 
C)  Submembranous cytoskeleton 
D)  Glycocalyx 
A)  Dense tubular system 
B)  Open canalicular system 
C)  Submembranous cytoskeleton 
D)  Glycocalyx

Question 8

Which of the following substances functions to stabilize platelet aggregates in the platelet plug?

Accepted Answer

A)  PDGF 
B)  Thrombospondin 
C)  Factor V receptor 
D)  PF4 
A)  PDGF 
B)  Thrombospondin 
C)  Factor V receptor 
D)  PF4

Question 9

Which of the following layers of blood vessels contains endothelial cells and is responsible for secreting procoagulant proteins to maintain tissue repair?

Accepted Answer

A)  Tunica adventitia 
B)  Tunica intima 
C)  Tunica media 
D)  Basement membrane 
A)  Tunica adventitia 
B)  Tunica intima 
C)  Tunica media 
D)  Basement membrane

Question 10

On average, how long does a platelet live in the peripheral circulation?

Accepted Answer

A)  6 hours 
B)  120 days 
C)  5 days 
D)  10 days 
A)  6 hours 
B)  120 days 
C)  5 days 
D)  10 days

Question 11

What is the first step in coagulation that occurs after vascular trauma?

Accepted Answer

A)  Vasoconstriction at the site of injury 
B)  Platelet adhesion to collagen 
C)  Platelet activation and shape change 
D)  Platelet aggregation to more platelets 
A)  Vasoconstriction at the site of injury 
B)  Platelet adhesion to collagen 
C)  Platelet activation and shape change 
D)  Platelet aggregation to more platelets

Question 12

Transient cessation of blood loss is achieved through which of the following?

Accepted Answer

A)  Formation of secondary hemostatic plug 
B)  Fibrinolysis of established thrombus 
C)  Formation of primary platelet plug 
D)  Inhibition of thrombus formation 
A)  Formation of secondary hemostatic plug 
B)  Fibrinolysis of established thrombus 
C)  Formation of primary platelet plug 
D)  Inhibition of thrombus formation

Exam 31: Primary Hemostasis

Sequential activation of plasma procoagulant proteins that induce the formation of insoluble blood proteins occurs in which phase of coagulation?

Which of the following is a role of platelets in secondary hemostasis?

Correlate blood vessel histology to vessel type and function in hemostasis.

After a blood vessel injury, which of the following initiates hemostasis?

Which of the following acts as a transport portal for granules to move from the organelle zone to the membrane zone?

Which of the following substances endogenous to the dense bodies is responsible for continuous platelet activation of surrounding platelets?

Which of the following is responsible for the platelet surface negative charge and is found on the surface membrane of the interior channels?

Which of the following substances functions to stabilize platelet aggregates in the platelet plug?

Which of the following layers of blood vessels contains endothelial cells and is responsible for secreting procoagulant proteins to maintain tissue repair?

On average, how long does a platelet live in the peripheral circulation?

What is the first step in coagulation that occurs after vascular trauma?

Transient cessation of blood loss is achieved through which of the following?

Introduction

Cellular Homeostasis

Structure and Function of Hematopoietic Organs

Hematopoiesis

The Erythrocyte

Hemoglobin

Granulocytes and Monocytes

Lymphocytes

The Platelet

The Complete Blood Count and Peripheral Blood Smear Evaluation

Introduction to Anemia

Anemias of Disordered Iron Metabolism and Heme Synthesis

Hemoglobinopathies: Qualitative Defects

Thalassemia

Megaloblastic and Nonmegaloblastic Macrocytic Anemias

Hypoproliferative Anemias

Hemolytic Anemia: Membrane Defects

Hemolytic Anemia: Enzyme Deficiencies

Hemolytic Anemia: Immune Anemias

Hemolytic Anemia: Nonimmune Defects

Nonmalignant Disorders of Leukocytes: Granulocytes and Monocytes

Nonmalignant Lymphocyte Disorders

Introduction to Hematopoietic Neoplasms

Myeloproliferative Neoplasms

Myelodysplastic Syndromes

Acute Myeloid Leukemias

Precursor Lymphoid Neoplasms

Mature Lymphoid Neoplasms

Hematopoietic Stem Cell Transplantation

Morphologic Analysis of Body Fluids in the Hematology

Secondary Hemostasis and Fibrinolysis

Disorders of Primary Hemostasis

Disorders of Secondary Hemostasis

Thrombophilia

Hemostasis: Laboratory Testing and Instrumentation

Hematology Procedures

Bone Marrow Examination

Automation in Hematology

Flow Cytometry

Chromosome Analysis of Hematopoietic and Lymphoid Disorders

Molecular Analysis of Hematologic Diseases

Quality Assessment in the Hematology Laboratory

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