Exam 38: Bone Marrow Examination

Identify Prussian blue iron stain results in the following disorders and explain your answers: a. Iron-deficiency anemia b. Anemia of chronic disease c. Thalassemia d. Sideroblastic anemia

What is the difference between a malignant lymphoid aggregate and a benign one?

A normal M:E ratio is about 3:1. A patient has three times more myeloid precursors than erythroid precursors in the bone marrow because:

What are the main reasons for using a core biopsy specimen versus an aspirate specimen?

The cellularity of the bone marrow is determined by examining the ratio of:

How many cells typically are counted when performing a bone marrow differential?

Which of the following is an expected finding in the bone marrow in a patient with the following results: serum iron = 124 mcg/dL (reference range: 35-170 ug/dL); TIBC = 284 mcg/dL (reference range: 225-425 mcg/dL)?

A 2-year-old boy is suspected of having leukemia, and a bone marrow examination is requested. From which body site should the bone marrow be collected?

The cellularity of the marrow is best examined in a ________, and it is determined by the red bone marrow's relationship to ________.

What would be the expected effect of chronic myelogenous leukemia on the M:E ratio?

All of the following are procedures in which a bone marrow aspirate is indicated except:

It has been determined that the M:E ratio of a 55-year-old patient is 12:1. What can be concluded about the cellularity of the bone marrow?

Name disorders in which the following should be included in the workup of a hematologic disorder. Explain why they are used. a. Flow cytometry b. Cytogenetics c. Molecular genetics d. Cytochemical staining