Exam 18: Regulation of Gene Expression

Imagine that you've isolated a yeast mutant that contains histones resistant to acetylation. What phenotype would you predict for this mutant?

Which of the following statements about the DNA in one of your brain cells is true?

What would occur if the repressor of an inducible operon were mutated so it could not bind the operator?

Which of the following functions are characteristic of general transcription factors in eukaryotes?

Most repressor proteins are allosteric. Which of the following molecules binds with the repressor to alter its conformation and therefore affect its function?

When the Bicoid protein is expressed in Drosophila, divisions between cells in the embryo are not yet fully developed. This information helps to explain which observation by Nüsslein-Volhard and Wieschaus?

A genetic test to detect predisposition to cancer would likely examine the APC gene for involvement in which type(s) of cancer?

A researcher introduces double-stranded RNA into a culture of mammalian cells and can identify its location or that of its smaller subsections experimentally, using a fluorescent probe. When she finds that the introduced strand separates into single-stranded RNAs, what other evidence of this single-stranded RNA piece's activity would she find?

Altering patterns of gene expression in prokaryotes would most likely serve an organism's survival by ________.

Gene expression is often assayed by measuring the level of mRNA produced from a gene. What level of the control of gene expression can by analysed by this type of assay?

Within a cell, the amount of protein made using a given mRNA molecule depends partly on

In positive control of several sugar metabolism-related operons, the cAMP receptor protein (CRP) binds to DNA to stimulate transcription. Which of the following environmental conditions causes an increase in CRP activity in stimulating transcription?

A researcher introduces double-stranded RNA into a culture of mammalian cells and can identify its location or that of its smaller subsections experimentally, using a fluorescent probe. Some time later, she finds that the introduced strand separates into single-stranded RNAs, one of which is degraded. What does this enable the remaining strand to do?

Which axis in the embryo does the protein product of the bicoid gene in Drosophila determine?

How do steroid hormones produce their effects in cells?

Which of the following molecules is a protein produced by a regulatory gene?

Which of the following results would occur if the repressor of an inducible operon were mutated so that it could not bind the operator?

A researcher found a method he could use to manipulate and quantify phosphorylation and methylation in embryonic cells in culture. In one set of experiments, he succeeded in increasing acetylation of histone tails in the chromatin of the cells. Which of the following results would he most likely see in these cells?

What essential information does the product of the bicoid gene in Drosophila provide during development?

DNA methylation and histone acetylation are examples of which of the following processes?