Question 1

A calculation that corrects for both the RBC count and presence of shift reticulocytes is called the ___________.

Accepted Answer

A)  Stress reticulocyte count 
B)  Corrected reticulocyte count 
C)  Reticulocyte production index (RPI) 
D)  Shift reticulocyte count 
E)  None of the above 
A)  Stress reticulocyte count 
B)  Corrected reticulocyte count 
C)  Reticulocyte production index (RPI) 
D)  Shift reticulocyte count 
E)  None of the above

Question 2

Red blood cells with an MCV of greater than 100 fL are said to be _______.

Accepted Answer

A)  Microcytic 
B)  Macrocytic 
C)  Normocytic 
D)  Hypochromic 
E)  None of the above 
A)  Microcytic 
B)  Macrocytic 
C)  Normocytic 
D)  Hypochromic 
E)  None of the above

Question 3

The osmotic fragility test is a measure of erythrocyte _________ .

Accepted Answer

A)  Size 
B)  Surface-to-volume ratio 
C)  Fragility of red cell organelles 
D)  All of the above 
E)  None of the above 
A)  Size 
B)  Surface-to-volume ratio 
C)  Fragility of red cell organelles 
D)  All of the above 
E)  None of the above

Question 4

The normal hematocrit value for an adult female is ______.

Accepted Answer

A)  37-47% 
B)  42-52% 
C)  53-65% 
D)  30-43% 
E)  None of the above 
A)  37-47% 
B)  42-52% 
C)  53-65% 
D)  30-43% 
E)  None of the above

Question 5

The normal WBC values for a newborn are ________.

Accepted Answer

A)  9-30 F1F1F1S1F1F1F10 109/L 
B)  5-21 F1F1F1S1F1F1F10 109/L 
C)  5-15 F1F1F1S1F1F1F10 109/L 
D)  4.8-10.8 F1F1F1S1F1F1F10 109/L 
E)  6.2-17 F1F1F1S1F1F1F10 109/L 
A)  9-30 F1F1F1S1F1F1F10 109/L 
B)  5-21 F1F1F1S1F1F1F10 109/L 
C)  5-15 F1F1F1S1F1F1F10 109/L 
D)  4.8-10.8 F1F1F1S1F1F1F10 109/L 
E)  6.2-17 F1F1F1S1F1F1F10 109/L

Question 6

In a manual RBC count, the difference between the highest and lowest number of cells of the 10 squares should be no greater than _______.

Accepted Answer

A)  20 
B)  10 
C)  25 
D)  15 
E)  30 
A)  20 
B)  10 
C)  25 
D)  15 
E)  30

Question 7

Calculate the MCH given the following: hematocrit = 33%, RBC = 3.3 F1F1F1S1F1F1F10 106/F1F1F1S1F1F1F10L, hemoglobin = 11.3 g/dL.

Accepted Answer

A)  27 pg 
B)  34 pg 
C)  31 pg 
D)  40 pg 
E)  None of the above 
A)  27 pg 
B)  34 pg 
C)  31 pg 
D)  40 pg 
E)  None of the above

Question 8

Normal values for the autohemolysis test at 48 hours with added dextrose are __________.

Accepted Answer

A)  0-1.0% 
B)  0.2-2.0% 
C)  0-0.8% 
D)  0-0.5% 
E)  None of the above 
A)  0-1.0% 
B)  0.2-2.0% 
C)  0-0.8% 
D)  0-0.5% 
E)  None of the above

Question 9

A reticulocyte count was performed using a Miller disc. A total of 25 reticulocytes were counted in the larger square and 900 red cells in the smaller square. What is the reticulocyte count expressed as a percentage?

Accepted Answer

A)  30% 
B)  3% 
C)  0.3% 
D)  5% 
E)  10% 
A)  30% 
B)  3% 
C)  0.3% 
D)  5% 
E)  10%

Question 10

The normal hematocrit range for a child is _______.

Accepted Answer

A)  37-42% 
B)  42-52% 
C)  53-65% 
D)  30-43% 
E)  None of the above 
A)  37-42% 
B)  42-52% 
C)  53-65% 
D)  30-43% 
E)  None of the above

Question 11

Heinz bodies are visualized in which area of a stained red cell?

Accepted Answer

A)  Periphery of the cell 
B)  Center of cell 
C)  Bipolar ends 
D)  All of the above 
E)  None of the above 
A)  Periphery of the cell 
B)  Center of cell 
C)  Bipolar ends 
D)  All of the above 
E)  None of the above

Question 12

A reticulocyte must contain _______ discrete blue granules to be counted.

Accepted Answer

A)  Five or more 
B)  One 
C)  Two or more 
D)  All of the above 
E)  None of the above 
A)  Five or more 
B)  One 
C)  Two or more 
D)  All of the above 
E)  None of the above

Question 13

Which forms of circulating hemoglobin are readily converted to cyanmethemoglobin?

Accepted Answer

A)  Oxyhemoglobin 
B)  Hemoglobin 
C)  Carboxyhemoglobin 
D)  All of the above 
E)  None of the above 
A)  Oxyhemoglobin 
B)  Hemoglobin 
C)  Carboxyhemoglobin 
D)  All of the above 
E)  None of the above

Question 14

What disease is represented by the following laboratory data? RBC count 3.0 F1F1F1S1F1F1F10 1012/µL
Hemoglobin 6.3 g/dL
Hematocrit 21%

Accepted Answer

A)  Iron-deficiency anemia 
B)  Thalassemia minor 
C)  Polycythemia vera 
D)  Pernicious anemia 
E)  Megaloblastic anemia 
A)  Iron-deficiency anemia 
B)  Thalassemia minor 
C)  Polycythemia vera 
D)  Pernicious anemia 
E)  Megaloblastic anemia

Question 15

The distance between the bottom of the cover slip and the surface of the counting area of the hemacytometer chamber is _______.

Accepted Answer

A)  1 mm 
B)  4 mm 
C)  0.1 mm 
D)  0.4 mm 
E)  None of the above 
A)  1 mm 
B)  4 mm 
C)  0.1 mm 
D)  0.4 mm 
E)  None of the above

Question 16

Reticulocytes are counted under _________ magnification.

Accepted Answer

A)  Low-power 
B)  High-power 
C)  Oil-immersion 
D)  Two of the above 
E)  None of the above 
A)  Low-power 
B)  High-power 
C)  Oil-immersion 
D)  Two of the above 
E)  None of the above

Question 17

Heinz bodies consist of _______.

Accepted Answer

A)  DNA 
B)  RNA 
C)  Denatured hemoglobin 
D)  Hemoglobin h bodies 
E)  None of the above 
A)  DNA 
B)  RNA 
C)  Denatured hemoglobin 
D)  Hemoglobin h bodies 
E)  None of the above

Question 18

A sample is drawn from a patient in a heparinized tube and sent to the hematology laboratory for an ESR determination. The laboratory technician sets up a Westergren tube according to the procedure. One hour later the technician checks the patient's tube and records the result as 43 mm/hr. The Quality Control for the day is in range. What should the technician do at this point?

Accepted Answer

A)  Report the results in the Laboratory Information System since the QC was in range. 
B)  Inform the physician of the results right away. 
C)  Call the nurse of the patient and request a new EDTA sample to repeat the test. 
D)  Call the nurse of the patient and request a new heparinized sample to repeat the test. 
E)  Use the same sample and repeat the test. 
A)  Report the results in the Laboratory Information System since the QC was in range. 
B)  Inform the physician of the results right away. 
C)  Call the nurse of the patient and request a new EDTA sample to repeat the test. 
D)  Call the nurse of the patient and request a new heparinized sample to repeat the test. 
E)  Use the same sample and repeat the test.

Question 19

When preparing a slide-to-slide blood smear:

Accepted Answer

A)  The spreader slide is held at a 30-degree angle 
B)  A small drop of blood is placed near the frosted end 
C)  A thin film of blood is made in the shape of a bullet with a feathered edge 
D)  Blood is allowed to air dry before staining 
E)  All of the above 
A)  The spreader slide is held at a 30-degree angle 
B)  A small drop of blood is placed near the frosted end 
C)  A thin film of blood is made in the shape of a bullet with a feathered edge 
D)  Blood is allowed to air dry before staining 
E)  All of the above

Question 20

The center primary square of the hemacytometer is divided into 25 smaller squares, each with an area of ______.

Accepted Answer

A)  0.02 mm2 
B)  0.04 mm2 
C)  1 mm2 
D)  4 mm2 
E)  None of the above 
A)  0.02 mm2 
B)  0.04 mm2 
C)  1 mm2 
D)  4 mm2 
E)  None of the above

Exam 31: Hematology Methods

A calculation that corrects for both the RBC count and presence of shift reticulocytes is called the ___________.

Red blood cells with an MCV of greater than 100 fL are said to be _______.

The osmotic fragility test is a measure of erythrocyte _________ .

The normal hematocrit value for an adult female is ______.

The normal WBC values for a newborn are ________.

In a manual RBC count, the difference between the highest and lowest number of cells of the 10 squares should be no greater than _______.

Calculate the MCH given the following: hematocrit = 33%, RBC = 3.3  106/L, hemoglobin = 11.3 g/dL.

Normal values for the autohemolysis test at 48 hours with added dextrose are __________.

A reticulocyte count was performed using a Miller disc. A total of 25 reticulocytes were counted in the larger square and 900 red cells in the smaller square. What is the reticulocyte count expressed as a percentage?

The normal hematocrit range for a child is _______.

Heinz bodies are visualized in which area of a stained red cell?

A reticulocyte must contain _______ discrete blue granules to be counted.

Which forms of circulating hemoglobin are readily converted to cyanmethemoglobin?

What disease is represented by the following laboratory data? RBC count 3.0  1012/µL Hemoglobin 6.3 g/dL Hematocrit 21%

The distance between the bottom of the cover slip and the surface of the counting area of the hemacytometer chamber is _______.

Reticulocytes are counted under _________ magnification.

Heinz bodies consist of _______.

When preparing a slide-to-slide blood smear:

The center primary square of the hemacytometer is divided into 25 smaller squares, each with an area of ______.

Morphology of Human Blood and Marrow Cells: Hematopoiesis

Bone Marrow

The Red Blood Cell: Structure and Function

Anemia: Diagnosis and Clinical Considerations

Evaluation of Red Blood Cell Morphology and Introduction to Platelet and White Blood Cell Morphology

Iron Metabolism and Hypochromic Anemias

Megaloblastic Anemias

Aplastic Anemia Including Pure Red Cell Aplasia and Congenital Dyserythropoietic Anemia and Paroxysmal Nocturnal Hemoglobinuria

Introduction to Hemolytic Anemias: Intracorpuscular Defects: I Hereditary Defects of the Red Cell Membrane

Hemolytic Anemias: Intracorpuscular Defects: II Hereditary Enzyme Deficiencies

Hemolytic Anemias: Intracorpuscular Defects: III the Hemoglobinopathies

Hemolytic Anemias: Intracorpuscular Defects: Iv Thalassemia

Hemolytic Anemias: Extracorpuscular Defects

Hypoproliferative Anemia: Anemia Associated With Systemic Diseases

Cell Biology, Disorders of Neutrophils, Infectious Mononucleosis, and Reactive Lymphocytosis

Introduction to Leukemia and the Acute Leukemias

Chronic Myeloproliferative Disorders I: Chronic Myelogenous Leukemia

Chronic Myeloproliferative Disorders Ii: Polycythemia Vera, Essential Thrombocythemia, and Idiopathic Myelofibrosis

Myelodysplastic Syndromes

Chronic Lymphocytic Leukemia and Related Lymphoproliferative Disorders

The Lymphomas

Multiple Myeloma and Related Plasma Cell Disorders

Lipid Lysosomal Storage Diseases and Histiocytosis

Introduction to Hemostasis

Disorders of Primary Hemostasis: Quantitative and Qualitative Platelet Disorders and Vascular Disorders

Disorders of Plasma Clotting Factors

Interaction of the Fibrinolytic, Coagulation, and Kinin Systems; Disseminated Intravascular Coagulation; and Related Pathology

Introduction to Thrombosis and Anticoagulant Therapy

Quality Control in the Hematology Laboratory

Body Fluid Examination: the Qualitative, Quantitative, and Morphologic Analysis of Serous, Cerebrospinal, and Synovial Fluids

Principles of Automated Differential Analysis

Coagulation Procedures

Applications of Flow Cytometry to Hematology and Hemostasis

Molecular Diagnostic Techniques in Hematopathology

Special Stainscytochemistry

Filters

Calculate the MCH given the following: hematocrit = 33%, RBC = 3.3  10⁶/L, hemoglobin = 11.3 g/dL.

What disease is represented by the following laboratory data? RBC count 3.0  10¹²/µL Hemoglobin 6.3 g/dL Hematocrit 21%