Question 1

Which of the following are common causes of iron deficiency anemia worldwide?

Accepted Answer

A)  Chronic blood loss 
B)  Inadequate diet and malabsorption 
C)  Pregnancy 
D)  Excessive menstrual blood loss (premenopausal women) 
E)  All of the above 
A)  Chronic blood loss 
B)  Inadequate diet and malabsorption 
C)  Pregnancy 
D)  Excessive menstrual blood loss (premenopausal women) 
E)  All of the above E

Question 2

Two-thirds of the total body iron is found as _________.

Accepted Answer

A)  Transferrin 
B)  Heme in hemoglobin 
C)  Heme in myoglobin 
D)  Globin in hemoglobin 
E)  None of the above 
A)  Transferrin 
B)  Heme in hemoglobin 
C)  Heme in myoglobin 
D)  Globin in hemoglobin 
E)  None of the above B

Question 3

Disorders commonly associated with anemia of chronic disease include:

Accepted Answer

A)  Infections 
B)  Malignant neoplasms 
C)  Autoimmune diseases 
D)  All of the above 
E)  None of the above 
A)  Infections 
B)  Malignant neoplasms 
C)  Autoimmune diseases 
D)  All of the above 
E)  None of the above D

Question 4

Iron-deficiency anemia is characterized by:

Accepted Answer

A)  Decreased serum iron, decreased ferritin, and increased total iron-binding capacity (TIB
C)  
B)  Increased serum iron , increased ferritin, and increased TIBC 
C)  Decreased serum iron, decreased ferritin, and decreased TIBC 
D)  Normal serum iron, decreased ferritin, and decreased TIBC 
E)  None of the above 
A)  Decreased serum iron, decreased ferritin, and increased total iron-binding capacity (TIB
C)  
B)  Increased serum iron , increased ferritin, and increased TIBC 
C)  Decreased serum iron, decreased ferritin, and decreased TIBC 
D)  Normal serum iron, decreased ferritin, and decreased TIBC 
E)  None of the above

Question 5

Which of the following represent(s) stained iron particles in the RBC?

Accepted Answer

A)  Heinz bodies 
B)  Howell-Jolly bodies 
C)  Pappenheimer bodies 
D)  Cabot rings 
E)  None of the above 
A)  Heinz bodies 
B)  Howell-Jolly bodies 
C)  Pappenheimer bodies 
D)  Cabot rings 
E)  None of the above

Question 6

Which pH facilitates ferrous iron absorption in the small intestines?

Accepted Answer

A)  Alkaline 
B)  Acidic 
C)  Neutral 
D)  Any of the above 
E)  None of the above 
A)  Alkaline 
B)  Acidic 
C)  Neutral 
D)  Any of the above 
E)  None of the above

Question 7

Iron-deficiency anemia is characterized by:

Accepted Answer

A)  Macrocytic, hyperchromic RBCs 
B)  Microcytic, hypochromic RBCs 
C)  Increased bone marrow storage iron 
D)  Increased bone marrow ringed sideroblasts 
E)  None of the above 
A)  Macrocytic, hyperchromic RBCs 
B)  Microcytic, hypochromic RBCs 
C)  Increased bone marrow storage iron 
D)  Increased bone marrow ringed sideroblasts 
E)  None of the above

Question 8

Hemosiderosis is the accumulation of excess __________ in the macrophages of various tissues.

Accepted Answer

A)  Iron 
B)  Heme 
C)  Hemopexin 
D)  Globin 
E)  All of the above 
A)  Iron 
B)  Heme 
C)  Hemopexin 
D)  Globin 
E)  All of the above

Question 9

Approximately how many milligrams (mg) of iron is lost during pregnancy?

Accepted Answer

A)  10 mg 
B)  100 mg 
C)  500 mg 
D)  1000 mg 
E)  5000 mg 
A)  10 mg 
B)  100 mg 
C)  500 mg 
D)  1000 mg 
E)  5000 mg

Question 10

Which of the following is readily absorbed by intestinal mucosal cells?

Accepted Answer

A)  Ferric iron (Fe3+) 
B)  Ferrous iron (Fe2+) 
C)  Hemosiderin 
D)  All of the above 
E)  None of the above 
A)  Ferric iron (Fe3+) 
B)  Ferrous iron (Fe2+) 
C)  Hemosiderin 
D)  All of the above 
E)  None of the above

Question 11

How many milligrams of iron are needed to produce 1 mL of red blood cells (RBCs)?

Accepted Answer

A)  1 mg 
B)  10 mg 
C)  20 mg 
D)  3 mg 
E)  0.5 mg 
A)  1 mg 
B)  10 mg 
C)  20 mg 
D)  3 mg 
E)  0.5 mg

Question 12

Which of the following is stored in macrophages and can be visualized in bone marrow aspirates by staining with Prussian blue?

Accepted Answer

A)  Hemosiderin 
B)  Transferrin 
C)  Hemopexin 
D)  Haptoglobin 
E)  None of the above 
A)  Hemosiderin 
B)  Transferrin 
C)  Hemopexin 
D)  Haptoglobin 
E)  None of the above

Question 13

Which of the following symptoms may suggest iron-deficiency anemia?

Accepted Answer

A)  Fatigue 
B)  Lethargy 
C)  Dizziness 
D)  All of the above 
E)  None of the above 
A)  Fatigue 
B)  Lethargy 
C)  Dizziness 
D)  All of the above 
E)  None of the above

Question 14

Which of the following characterize(s) the microcytic hypochromic sideroblastic anemia?

Accepted Answer

A)  Increased ringed sideroblasts 
B)  Increased serum ferritin 
C)  Dimorphic blood picture 
D)  Basophilic stippling 
E)  All of the above 
A)  Increased ringed sideroblasts 
B)  Increased serum ferritin 
C)  Dimorphic blood picture 
D)  Basophilic stippling 
E)  All of the above

Question 15

Iron absorption is influenced by which of the following?

Accepted Answer

A)  Amount and type of iron accessible from food 
B)  Functional state of the gastrointestinal mucosa and pancreas 
C)  Current iron stores 
D)  Erythropoietic needs 
E)  All of the above 
A)  Amount and type of iron accessible from food 
B)  Functional state of the gastrointestinal mucosa and pancreas 
C)  Current iron stores 
D)  Erythropoietic needs 
E)  All of the above

Question 16

For pregnant women, what are the minimum daily requirements for iron and the corresponding iron content of food required?

Accepted Answer

A)  1.0 mg/10 mg 
B)  2.0 mg/20 mg 
C)  3.0 mg/30 mg 
D)  0.5 mg/5 mg 
A)  1.0 mg/10 mg 
B)  2.0 mg/20 mg 
C)  3.0 mg/30 mg 
D)  0.5 mg/5 mg

Question 17

What are the minimal daily requirements for iron and the corresponding iron content of food required for men and nonmenstruating females?

Accepted Answer

A)  1.0 mg/10 mg 
B)  2.0 mg/20 mg 
C)  3.0 mg/30 mg 
D)  0.5 mg/5 mg 
A)  1.0 mg/10 mg 
B)  2.0 mg/20 mg 
C)  3.0 mg/30 mg 
D)  0.5 mg/5 mg

Question 18

For infants, what are the minimal daily requirements for iron and the corresponding iron content of food required?

Accepted Answer

A)  1.0 mg/10 mg 
B)  2.0 mg/20 mg 
C)  3.0 mg/30 mg 
D)  0.5 mg/5 mg 
A)  1.0 mg/10 mg 
B)  2.0 mg/20 mg 
C)  3.0 mg/30 mg 
D)  0.5 mg/5 mg

Question 19

What are the minimal daily requirements for iron and the corresponding iron content of food required for menstruating females?

Accepted Answer

A)  1.0 mg/10 mg 
B)  2.0 mg/20 mg 
C)  3.0 mg/30 mg 
D)  0.5 mg/5 mg 
A)  1.0 mg/10 mg 
B)  2.0 mg/20 mg 
C)  3.0 mg/30 mg 
D)  0.5 mg/5 mg

Question 20

The majority of the daily iron requirements for production of RBCs is released during daily RBC turnover of aged red cells and is called __________.

Accepted Answer

A)  Recycled iron 
B)  Stored body iron 
C)  Myoglobin iron 
D)  Absorbed iron 
E)  Hemosiderin 
A)  Recycled iron 
B)  Stored body iron 
C)  Myoglobin iron 
D)  Absorbed iron 
E)  Hemosiderin

Exam 6: Iron Metabolism and Hypochromic Anemias

Which of the following are common causes of iron deficiency anemia worldwide?

Two-thirds of the total body iron is found as _________.

Disorders commonly associated with anemia of chronic disease include:

Iron-deficiency anemia is characterized by:

Which of the following represent(s) stained iron particles in the RBC?

Which pH facilitates ferrous iron absorption in the small intestines?

Iron-deficiency anemia is characterized by:

Hemosiderosis is the accumulation of excess __________ in the macrophages of various tissues.

Approximately how many milligrams (mg) of iron is lost during pregnancy?

Which of the following is readily absorbed by intestinal mucosal cells?

How many milligrams of iron are needed to produce 1 mL of red blood cells (RBCs)?

Which of the following is stored in macrophages and can be visualized in bone marrow aspirates by staining with Prussian blue?

Which of the following symptoms may suggest iron-deficiency anemia?

Which of the following characterize(s) the microcytic hypochromic sideroblastic anemia?

Iron absorption is influenced by which of the following?

For pregnant women, what are the minimum daily requirements for iron and the corresponding iron content of food required?

What are the minimal daily requirements for iron and the corresponding iron content of food required for men and nonmenstruating females?

For infants, what are the minimal daily requirements for iron and the corresponding iron content of food required?

What are the minimal daily requirements for iron and the corresponding iron content of food required for menstruating females?

The majority of the daily iron requirements for production of RBCs is released during daily RBC turnover of aged red cells and is called __________.

Morphology of Human Blood and Marrow Cells: Hematopoiesis

Bone Marrow

The Red Blood Cell: Structure and Function

Anemia: Diagnosis and Clinical Considerations

Evaluation of Red Blood Cell Morphology and Introduction to Platelet and White Blood Cell Morphology

Megaloblastic Anemias

Aplastic Anemia Including Pure Red Cell Aplasia and Congenital Dyserythropoietic Anemia and Paroxysmal Nocturnal Hemoglobinuria

Introduction to Hemolytic Anemias: Intracorpuscular Defects: I Hereditary Defects of the Red Cell Membrane

Hemolytic Anemias: Intracorpuscular Defects: II Hereditary Enzyme Deficiencies

Hemolytic Anemias: Intracorpuscular Defects: III the Hemoglobinopathies

Hemolytic Anemias: Intracorpuscular Defects: Iv Thalassemia

Hemolytic Anemias: Extracorpuscular Defects

Hypoproliferative Anemia: Anemia Associated With Systemic Diseases

Cell Biology, Disorders of Neutrophils, Infectious Mononucleosis, and Reactive Lymphocytosis

Introduction to Leukemia and the Acute Leukemias

Chronic Myeloproliferative Disorders I: Chronic Myelogenous Leukemia

Chronic Myeloproliferative Disorders Ii: Polycythemia Vera, Essential Thrombocythemia, and Idiopathic Myelofibrosis

Myelodysplastic Syndromes

Chronic Lymphocytic Leukemia and Related Lymphoproliferative Disorders

The Lymphomas

Multiple Myeloma and Related Plasma Cell Disorders

Lipid Lysosomal Storage Diseases and Histiocytosis

Introduction to Hemostasis

Disorders of Primary Hemostasis: Quantitative and Qualitative Platelet Disorders and Vascular Disorders

Disorders of Plasma Clotting Factors

Interaction of the Fibrinolytic, Coagulation, and Kinin Systems; Disseminated Intravascular Coagulation; and Related Pathology

Introduction to Thrombosis and Anticoagulant Therapy

Quality Control in the Hematology Laboratory

Body Fluid Examination: the Qualitative, Quantitative, and Morphologic Analysis of Serous, Cerebrospinal, and Synovial Fluids

Hematology Methods

Principles of Automated Differential Analysis

Coagulation Procedures

Applications of Flow Cytometry to Hematology and Hemostasis

Molecular Diagnostic Techniques in Hematopathology

Special Stainscytochemistry

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