Question 1

The storage form of iron is called __________.

Accepted Answer

A)  Ferrous iron 
B)  Hemopexin 
C)  Transferrin 
D)  Ferritin 
E)  None of the above 
A)  Ferrous iron 
B)  Hemopexin 
C)  Transferrin 
D)  Ferritin 
E)  None of the above

Question 2

What percentage of total body iron is present as plasma/transport iron?

Accepted Answer

A)  1% 
B)  5% 
C)  20% 
D)  50% 
E)  10% 
A)  1% 
B)  5% 
C)  20% 
D)  50% 
E)  10%

Question 3

Which of the following disorders represent(s) a problem in forming the RBC hemoglobin molecule, resulting in a microcytic hypochromic anemia?

Accepted Answer

A)  Iron-deficiency anemia 
B)  Sideroblastic anemia 
C)  Thalassemia 
D)  All of the above 
E)  None of the above 
A)  Iron-deficiency anemia 
B)  Sideroblastic anemia 
C)  Thalassemia 
D)  All of the above 
E)  None of the above

Question 4

Which of the following laboratory results characterize(s) iron-deficiency anemia?

Accepted Answer

A)  Decreased hemoglobin 
B)  Decreased MCV (mean corpuscular volume) 
C)  Decreased MCH (mean corpuscular hemoglobin) 
D)  Decreased MCHC (mean corpuscular hemoglobin concentration) 
E)  All of the above 
A)  Decreased hemoglobin 
B)  Decreased MCV (mean corpuscular volume) 
C)  Decreased MCH (mean corpuscular hemoglobin) 
D)  Decreased MCHC (mean corpuscular hemoglobin concentration) 
E)  All of the above

Question 5

Which of the following represent(s) an acquired sideroblastic anemia producing a microcytic hypochromic anemia with basophilic stippling, skin lesions, and neurologic dysfunction?

Accepted Answer

A)  Inflammation 
B)  Lead poisoning 
C)  Iron-deficiency anemia 
D)  Anemia of chronic disease 
E)  All of the above 
A)  Inflammation 
B)  Lead poisoning 
C)  Iron-deficiency anemia 
D)  Anemia of chronic disease 
E)  All of the above

Question 6

Which of the following is (are) characteristic of lead poisoning?

Accepted Answer

A)  Basophilic stippling in RBCs 
B)  Increased free erythrocyte protoporphyrin (FEP) 
C)  Microcytic hypochromic anemia 
D)  All of the above 
E)  None of the above 
A)  Basophilic stippling in RBCs 
B)  Increased free erythrocyte protoporphyrin (FEP) 
C)  Microcytic hypochromic anemia 
D)  All of the above 
E)  None of the above

Question 7

Which of the following characterizes the microcytic, hypochromic anemia of chronic disease or infection?

Accepted Answer

A)  Increases marrow iron 
B)  Decreases serum iron 
C)  Normal to increased serum ferritin 
D)  Decreased TIBC 
E)  All of the above 
A)  Increases marrow iron 
B)  Decreases serum iron 
C)  Normal to increased serum ferritin 
D)  Decreased TIBC 
E)  All of the above

Question 8

Which of the following is a beta globulin synthesized in the liver and a transport protein specific for iron?

Accepted Answer

A)  Haptoglobin 
B)  Albumin 
C)  Transferrin 
D)  Hemopexin 
E)  None of the above 
A)  Haptoglobin 
B)  Albumin 
C)  Transferrin 
D)  Hemopexin 
E)  None of the above

Question 9

Approximately what percent of ingested iron is absorbed?

Accepted Answer

A)  1% 
B)  5-10% 
C)  25-50% 
D)  90% 
E)  None of the above 
A)  1% 
B)  5-10% 
C)  25-50% 
D)  90% 
E)  None of the above

Question 10

One-third of the total body iron may be found in storage pools such as:

Accepted Answer

A)  Bone marrow 
B)  Liver 
C)  Spleen 
D)  All of the above 
E)  None of the above 
A)  Bone marrow 
B)  Liver 
C)  Spleen 
D)  All of the above 
E)  None of the above

Question 11

To carry oxygen iron must be in what state in the heme of the hemoglobin molecule?

Accepted Answer

A)  Ferric (Fe3+) 
B)  Carboxylated iron 
C)  Ferrous (Fe2+) 
D)  Metheme 
E)  None of the above 
A)  Ferric (Fe3+) 
B)  Carboxylated iron 
C)  Ferrous (Fe2+) 
D)  Metheme 
E)  None of the above

Exam 6: Iron Metabolism and Hypochromic Anemias

The storage form of iron is called __________.

What percentage of total body iron is present as plasma/transport iron?

Which of the following disorders represent(s) a problem in forming the RBC hemoglobin molecule, resulting in a microcytic hypochromic anemia?

Which of the following laboratory results characterize(s) iron-deficiency anemia?

Which of the following represent(s) an acquired sideroblastic anemia producing a microcytic hypochromic anemia with basophilic stippling, skin lesions, and neurologic dysfunction?

Which of the following is (are) characteristic of lead poisoning?

Which of the following characterizes the microcytic, hypochromic anemia of chronic disease or infection?

Which of the following is a beta globulin synthesized in the liver and a transport protein specific for iron?

Approximately what percent of ingested iron is absorbed?

One-third of the total body iron may be found in storage pools such as:

To carry oxygen iron must be in what state in the heme of the hemoglobin molecule?

Morphology of Human Blood and Marrow Cells: Hematopoiesis

Bone Marrow

The Red Blood Cell: Structure and Function

Anemia: Diagnosis and Clinical Considerations

Evaluation of Red Blood Cell Morphology and Introduction to Platelet and White Blood Cell Morphology

Megaloblastic Anemias

Aplastic Anemia Including Pure Red Cell Aplasia and Congenital Dyserythropoietic Anemia and Paroxysmal Nocturnal Hemoglobinuria

Introduction to Hemolytic Anemias: Intracorpuscular Defects: I Hereditary Defects of the Red Cell Membrane

Hemolytic Anemias: Intracorpuscular Defects: II Hereditary Enzyme Deficiencies

Hemolytic Anemias: Intracorpuscular Defects: III the Hemoglobinopathies

Hemolytic Anemias: Intracorpuscular Defects: Iv Thalassemia

Hemolytic Anemias: Extracorpuscular Defects

Hypoproliferative Anemia: Anemia Associated With Systemic Diseases

Cell Biology, Disorders of Neutrophils, Infectious Mononucleosis, and Reactive Lymphocytosis

Introduction to Leukemia and the Acute Leukemias

Chronic Myeloproliferative Disorders I: Chronic Myelogenous Leukemia

Chronic Myeloproliferative Disorders Ii: Polycythemia Vera, Essential Thrombocythemia, and Idiopathic Myelofibrosis

Myelodysplastic Syndromes

Chronic Lymphocytic Leukemia and Related Lymphoproliferative Disorders

The Lymphomas

Multiple Myeloma and Related Plasma Cell Disorders

Lipid Lysosomal Storage Diseases and Histiocytosis

Introduction to Hemostasis

Disorders of Primary Hemostasis: Quantitative and Qualitative Platelet Disorders and Vascular Disorders

Disorders of Plasma Clotting Factors

Interaction of the Fibrinolytic, Coagulation, and Kinin Systems; Disseminated Intravascular Coagulation; and Related Pathology

Introduction to Thrombosis and Anticoagulant Therapy

Quality Control in the Hematology Laboratory

Body Fluid Examination: the Qualitative, Quantitative, and Morphologic Analysis of Serous, Cerebrospinal, and Synovial Fluids

Hematology Methods

Principles of Automated Differential Analysis

Coagulation Procedures

Applications of Flow Cytometry to Hematology and Hemostasis

Molecular Diagnostic Techniques in Hematopathology

Special Stainscytochemistry

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