Question 1

Reactive lymphocytes are present in the evaluation of certain diseases such as:

Accepted Answer

A)  Infectious mononucleosis 
B)  Cancer 
C)  Bacterial infections 
D)  Tumors 
E)  Anemias 
A)  Infectious mononucleosis 
B)  Cancer 
C)  Bacterial infections 
D)  Tumors 
E)  Anemias A

Question 2

Evaluate the clinical use of interleukins:

Accepted Answer

A)  Wound healing 
B)  Activating lymphocytes 
C)  Assisting in growth of bone marrow 
D)  B and C 
E)  All are correct 
A)  Wound healing 
B)  Activating lymphocytes 
C)  Assisting in growth of bone marrow 
D)  B and C 
E)  All are correct E

Question 3

Ultimately, megakaryocytes lead to the formation of non-nucleated, cytoplasmic fragments called:

Accepted Answer

A)  Granulocytes 
B)  Thrombocytes 
C)  Lymphocytes 
D)  Monocytes 
E)  None of the above 
A)  Granulocytes 
B)  Thrombocytes 
C)  Lymphocytes 
D)  Monocytes 
E)  None of the above B

Question 4

An alteration in the megakaryoblast might occur in which disease state?

Accepted Answer

A)  Iron-deficiency anemia 
B)  Chronic granulocytic leukemia 
C)  Chronic lymphocytic leukemia 
D)  Thalassemia 
E)  None of the above 
A)  Iron-deficiency anemia 
B)  Chronic granulocytic leukemia 
C)  Chronic lymphocytic leukemia 
D)  Thalassemia 
E)  None of the above

Question 5

What percentage of band neutrophils is present in the peripheral blood?

Accepted Answer

A)  1-4% 
B)  2-6% 
C)  10-12% 
D)  4-8% 
E)  None of the above 
A)  1-4% 
B)  2-6% 
C)  10-12% 
D)  4-8% 
E)  None of the above

Question 6

What function do mast cells and basophils serve?

Accepted Answer

A)  Oxygen supply to tissues 
B)  Phagocytosis in parasitic infections 
C)  Histamine release in allergic reactions 
D)  Cell-mediated immunity 
E)  None of the above 
A)  Oxygen supply to tissues 
B)  Phagocytosis in parasitic infections 
C)  Histamine release in allergic reactions 
D)  Cell-mediated immunity 
E)  None of the above

Question 7

What color does the cytoplasm of eosinophils retain on Wright's stain?

Accepted Answer

A)  Bluish-purple 
B)  Reddish-orange 
C)  Reddish-pink 
D)  Purple-black 
E)  None of the above 
A)  Bluish-purple 
B)  Reddish-orange 
C)  Reddish-pink 
D)  Purple-black 
E)  None of the above

Question 8

Plasmacytes represent the end stage of what cell lineage?

Accepted Answer

A)  B lymphocytes 
B)  T lymphocytes 
C)  Prolymphocytes 
D)  Lymphoblasts 
E)  Megakaryocyte 
A)  B lymphocytes 
B)  T lymphocytes 
C)  Prolymphocytes 
D)  Lymphoblasts 
E)  Megakaryocyte

Question 9

The hematopoietic system consists of the:

Accepted Answer

A)  Thymus 
B)  Bone marrow 
C)  Liver 
D)  Spleen 
E)  All of the above 
A)  Thymus 
B)  Bone marrow 
C)  Liver 
D)  Spleen 
E)  All of the above

Question 10

What disease state can be associated with the presence of tissue neutrophils in bone marrow?

Accepted Answer

A)  Myelocytic leukemia 
B)  Erythroleukemia 
C)  Acute lymphocytic leukemia 
D)  Non-Hodgkin's lymphoma 
E)  None of the above 
A)  Myelocytic leukemia 
B)  Erythroleukemia 
C)  Acute lymphocytic leukemia 
D)  Non-Hodgkin's lymphoma 
E)  None of the above

Question 11

What is the sequence of maturity for the erythrocyte?

Accepted Answer

A)  Rubriblast, prorubricyte, metarubricyte, rubricyte, reticulocyte, erythrocyte 
B)  Prorubricyte, rubriblast, metarubricyte, reticulocyte, erythrocyte, rubricyte 
C)  Metarubricyte, rubriblast, reticulocyte, erythrocyte, prorubricyte, rubricyte 
D)  Rubricyte, metarubricyte, rubriblast, erythrocyte, reticulocyte, prorubricyte 
E)  Rubriblast, prorubricyte, rubricyte, metarubricyte, reticulocyte, erythrocyte 
A)  Rubriblast, prorubricyte, metarubricyte, rubricyte, reticulocyte, erythrocyte 
B)  Prorubricyte, rubriblast, metarubricyte, reticulocyte, erythrocyte, rubricyte 
C)  Metarubricyte, rubriblast, reticulocyte, erythrocyte, prorubricyte, rubricyte 
D)  Rubricyte, metarubricyte, rubriblast, erythrocyte, reticulocyte, prorubricyte 
E)  Rubriblast, prorubricyte, rubricyte, metarubricyte, reticulocyte, erythrocyte

Question 12

What percentage of erythrocytes is functional in peripheral blood after release from the bone marrow?

Accepted Answer

A)  70% 
B)  50% 
C)  80% 
D)  100% 
E)  None of the above 
A)  70% 
B)  50% 
C)  80% 
D)  100% 
E)  None of the above

Question 13

What stages do both basophils and eosinophils pass through in their sequence of maturity?

Accepted Answer

A)  Promyelocyte, myelocyte, band cell, segmented cell 
B)  Myeloblast, promyelocyte, myelocyte, band cell, segmented cell 
C)  Myelocyte, metamyelocyte, band cell, segmented cell 
D)  Band cell, myelocyte, metamyelocyte, segmented cell 
E)  None of the above 
A)  Promyelocyte, myelocyte, band cell, segmented cell 
B)  Myeloblast, promyelocyte, myelocyte, band cell, segmented cell 
C)  Myelocyte, metamyelocyte, band cell, segmented cell 
D)  Band cell, myelocyte, metamyelocyte, segmented cell 
E)  None of the above

Question 14

What is the average diameter of a normal erythrocyte?

Accepted Answer

A)  3-5 µm 
B)  2-4 µm 
C)  8-10 µm 
D)  7-8 µm 
E)  None of the above 
A)  3-5 µm 
B)  2-4 µm 
C)  8-10 µm 
D)  7-8 µm 
E)  None of the above

Question 15

The stage in granulocyte maturation where the nucleus appears kidney shaped is evident in what cell?

Accepted Answer

A)  Promyelocyte 
B)  Band neutrophil 
C)  Metamyelocyte 
D)  Myelocyte 
E)  None of the above 
A)  Promyelocyte 
B)  Band neutrophil 
C)  Metamyelocyte 
D)  Myelocyte 
E)  None of the above

Question 16

The first sign of neutrophilic differentiation and appearance of secondary granules is evident in what cell type?

Accepted Answer

A)  Promyelocyte 
B)  Myelocyte 
C)  Segmented neutrophil 
D)  Metamyelocyte 
E)  None of the above 
A)  Promyelocyte 
B)  Myelocyte 
C)  Segmented neutrophil 
D)  Metamyelocyte 
E)  None of the above

Question 17

By increasing hematopoiesis, the hematopoietic system can respond to stimuli such as:

Accepted Answer

A)  Infection 
B)  Bleeding 
C)  Hypoxia 
D)  All of the above 
E)  None of the above 
A)  Infection 
B)  Bleeding 
C)  Hypoxia 
D)  All of the above 
E)  None of the above

Question 18

What is meant by medullary hematopoiesis?

Accepted Answer

A)  Hematopoiesis in the spleen 
B)  Hematopoiesis in marrow 
C)  Hematopoiesis in liver 
D)  Hematopoiesis in thymus 
E)  None of the above 
A)  Hematopoiesis in the spleen 
B)  Hematopoiesis in marrow 
C)  Hematopoiesis in liver 
D)  Hematopoiesis in thymus 
E)  None of the above

Question 19

What characteristics are helpful in the identification of monocytes?

Accepted Answer

A)  Gray-blue cytoplasm 
B)  Digestive vacuoles 
C)  Lacy, delicate chromatin and indented nucleus 
D)  "Ground-glass" appearance of cytoplasm with evenly distributed fine granules 
E)  All of the above 
A)  Gray-blue cytoplasm 
B)  Digestive vacuoles 
C)  Lacy, delicate chromatin and indented nucleus 
D)  "Ground-glass" appearance of cytoplasm with evenly distributed fine granules 
E)  All of the above

Question 20

What percentage of lymphocytes is present in peripheral blood?

Accepted Answer

A)  50-70% 
B)  20-44% 
C)  10-30% 
D)  5-10% 
E)  None of the above 
A)  50-70% 
B)  20-44% 
C)  10-30% 
D)  5-10% 
E)  None of the above

Exam 1: Morphology of Human Blood and Marrow Cells: Hematopoiesis

Reactive lymphocytes are present in the evaluation of certain diseases such as:

Evaluate the clinical use of interleukins:

Ultimately, megakaryocytes lead to the formation of non-nucleated, cytoplasmic fragments called:

An alteration in the megakaryoblast might occur in which disease state?

What percentage of band neutrophils is present in the peripheral blood?

What function do mast cells and basophils serve?

What color does the cytoplasm of eosinophils retain on Wright's stain?

Plasmacytes represent the end stage of what cell lineage?

The hematopoietic system consists of the:

What disease state can be associated with the presence of tissue neutrophils in bone marrow?

What is the sequence of maturity for the erythrocyte?

What percentage of erythrocytes is functional in peripheral blood after release from the bone marrow?

What stages do both basophils and eosinophils pass through in their sequence of maturity?

What is the average diameter of a normal erythrocyte?

The stage in granulocyte maturation where the nucleus appears kidney shaped is evident in what cell?

The first sign of neutrophilic differentiation and appearance of secondary granules is evident in what cell type?

By increasing hematopoiesis, the hematopoietic system can respond to stimuli such as:

What is meant by medullary hematopoiesis?

What characteristics are helpful in the identification of monocytes?

What percentage of lymphocytes is present in peripheral blood?

Bone Marrow

The Red Blood Cell: Structure and Function

Anemia: Diagnosis and Clinical Considerations

Evaluation of Red Blood Cell Morphology and Introduction to Platelet and White Blood Cell Morphology

Iron Metabolism and Hypochromic Anemias

Megaloblastic Anemias

Aplastic Anemia Including Pure Red Cell Aplasia and Congenital Dyserythropoietic Anemia and Paroxysmal Nocturnal Hemoglobinuria

Introduction to Hemolytic Anemias: Intracorpuscular Defects: I Hereditary Defects of the Red Cell Membrane

Hemolytic Anemias: Intracorpuscular Defects: II Hereditary Enzyme Deficiencies

Hemolytic Anemias: Intracorpuscular Defects: III the Hemoglobinopathies

Hemolytic Anemias: Intracorpuscular Defects: Iv Thalassemia

Hemolytic Anemias: Extracorpuscular Defects

Hypoproliferative Anemia: Anemia Associated With Systemic Diseases

Cell Biology, Disorders of Neutrophils, Infectious Mononucleosis, and Reactive Lymphocytosis

Introduction to Leukemia and the Acute Leukemias

Chronic Myeloproliferative Disorders I: Chronic Myelogenous Leukemia

Chronic Myeloproliferative Disorders Ii: Polycythemia Vera, Essential Thrombocythemia, and Idiopathic Myelofibrosis

Myelodysplastic Syndromes

Chronic Lymphocytic Leukemia and Related Lymphoproliferative Disorders

The Lymphomas

Multiple Myeloma and Related Plasma Cell Disorders

Lipid Lysosomal Storage Diseases and Histiocytosis

Introduction to Hemostasis

Disorders of Primary Hemostasis: Quantitative and Qualitative Platelet Disorders and Vascular Disorders

Disorders of Plasma Clotting Factors

Interaction of the Fibrinolytic, Coagulation, and Kinin Systems; Disseminated Intravascular Coagulation; and Related Pathology

Introduction to Thrombosis and Anticoagulant Therapy

Quality Control in the Hematology Laboratory

Body Fluid Examination: the Qualitative, Quantitative, and Morphologic Analysis of Serous, Cerebrospinal, and Synovial Fluids

Hematology Methods

Principles of Automated Differential Analysis

Coagulation Procedures

Applications of Flow Cytometry to Hematology and Hemostasis

Molecular Diagnostic Techniques in Hematopathology

Special Stainscytochemistry

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