Question 1

Which of the following is the largest hematopoietic cell in the bone marrow?

Accepted Answer

A)  Pronormoblast 
B)  Myeloblast 
C)  Megakaryocyte 
D)  Monoblast 
E)  Plasma cell 
A)  Pronormoblast 
B)  Myeloblast 
C)  Megakaryocyte 
D)  Monoblast 
E)  Plasma cell

Question 2

Which cell in the granulocytic series is present in greatest percentages in the normal bone marrow?

Accepted Answer

A)  Band neutrophil 
B)  Promyelocyte 
C)  Metamyelocyte 
D)  Myelocyte 
E)  None of the above 
A)  Band neutrophil 
B)  Promyelocyte 
C)  Metamyelocyte 
D)  Myelocyte 
E)  None of the above

Question 3

What cell does the monocyte become upon entering the tissues?

Accepted Answer

A)  Lymphocyte 
B)  Mast cell 
C)  Macrophage 
D)  Neutrophil 
E)  None of the above 
A)  Lymphocyte 
B)  Mast cell 
C)  Macrophage 
D)  Neutrophil 
E)  None of the above

Question 4

Where does T-cell differentiation take place?

Accepted Answer

A)  Thymus 
B)  Bone marrow 
C)  Liver 
D)  Spleen 
E)  None of the above 
A)  Thymus 
B)  Bone marrow 
C)  Liver 
D)  Spleen 
E)  None of the above

Question 5

The lymphoblast can be identified morphologically by what characteristics?

Accepted Answer

A)  Small round nucleus, basophilic cytoplasm, nucleoli 
B)  Large round nucleus, basophilic cytoplasm, no nucleoli 
C)  Small eccentric nucleus, basophilic cytoplasm, nucleoli 
D)  Large round nucleus, basophilic cytoplasm, nucleoli 
E)  None of the above 
A)  Small round nucleus, basophilic cytoplasm, nucleoli 
B)  Large round nucleus, basophilic cytoplasm, no nucleoli 
C)  Small eccentric nucleus, basophilic cytoplasm, nucleoli 
D)  Large round nucleus, basophilic cytoplasm, nucleoli 
E)  None of the above

Question 6

The maturation of the granulocytic series is characterized by:

Accepted Answer

A)  Decrease in nuclear volume 
B)  Appearance and disappearance of primary granules 
C)  Nuclear chromatin clumping 
D)  Cytoplasmic color change from blue to pink appearance of secondary granules 
E)  All of the above 
A)  Decrease in nuclear volume 
B)  Appearance and disappearance of primary granules 
C)  Nuclear chromatin clumping 
D)  Cytoplasmic color change from blue to pink appearance of secondary granules 
E)  All of the above

Question 7

The sequence of maturity of the mature neutrophil is:

Accepted Answer

A)  Myeloblast, promyelocyte, myelocyte, metamyelocyte, band neutrophil, segmented neutrophil 
B)  Myeloblast, promyelocyte, metamyelocyte, myelocyte, band neutrophil, segmented neutrophil 
C)  Myeloblast, promyelocyte, band neutrophil, metamyelocyte, myelocyte, segmented neutrophil 
D)  Myeloblast, myelocyte, promyelocyte, metamyelocyte, band neutrophil, segmented neutrophil 
E)  None of the above 
A)  Myeloblast, promyelocyte, myelocyte, metamyelocyte, band neutrophil, segmented neutrophil 
B)  Myeloblast, promyelocyte, metamyelocyte, myelocyte, band neutrophil, segmented neutrophil 
C)  Myeloblast, promyelocyte, band neutrophil, metamyelocyte, myelocyte, segmented neutrophil 
D)  Myeloblast, myelocyte, promyelocyte, metamyelocyte, band neutrophil, segmented neutrophil 
E)  None of the above

Question 8

In which immature erythroid cell are nucleoli most visible?

Accepted Answer

A)  Basophilic normoblast 
B)  Orthochromatic normoblast 
C)  Pronormoblast 
D)  Polychromatic normoblast 
E)  None of the above 
A)  Basophilic normoblast 
B)  Orthochromatic normoblast 
C)  Pronormoblast 
D)  Polychromatic normoblast 
E)  None of the above

Exam 1: Morphology of Human Blood and Marrow Cells: Hematopoiesis

Which of the following is the largest hematopoietic cell in the bone marrow?

Which cell in the granulocytic series is present in greatest percentages in the normal bone marrow?

What cell does the monocyte become upon entering the tissues?

Where does T-cell differentiation take place?

The lymphoblast can be identified morphologically by what characteristics?

The maturation of the granulocytic series is characterized by:

The sequence of maturity of the mature neutrophil is:

In which immature erythroid cell are nucleoli most visible?

Bone Marrow

The Red Blood Cell: Structure and Function

Anemia: Diagnosis and Clinical Considerations

Evaluation of Red Blood Cell Morphology and Introduction to Platelet and White Blood Cell Morphology

Iron Metabolism and Hypochromic Anemias

Megaloblastic Anemias

Aplastic Anemia Including Pure Red Cell Aplasia and Congenital Dyserythropoietic Anemia and Paroxysmal Nocturnal Hemoglobinuria

Introduction to Hemolytic Anemias: Intracorpuscular Defects: I Hereditary Defects of the Red Cell Membrane

Hemolytic Anemias: Intracorpuscular Defects: II Hereditary Enzyme Deficiencies

Hemolytic Anemias: Intracorpuscular Defects: III the Hemoglobinopathies

Hemolytic Anemias: Intracorpuscular Defects: Iv Thalassemia

Hemolytic Anemias: Extracorpuscular Defects

Hypoproliferative Anemia: Anemia Associated With Systemic Diseases

Cell Biology, Disorders of Neutrophils, Infectious Mononucleosis, and Reactive Lymphocytosis

Introduction to Leukemia and the Acute Leukemias

Chronic Myeloproliferative Disorders I: Chronic Myelogenous Leukemia

Chronic Myeloproliferative Disorders Ii: Polycythemia Vera, Essential Thrombocythemia, and Idiopathic Myelofibrosis

Myelodysplastic Syndromes

Chronic Lymphocytic Leukemia and Related Lymphoproliferative Disorders

The Lymphomas

Multiple Myeloma and Related Plasma Cell Disorders

Lipid Lysosomal Storage Diseases and Histiocytosis

Introduction to Hemostasis

Disorders of Primary Hemostasis: Quantitative and Qualitative Platelet Disorders and Vascular Disorders

Disorders of Plasma Clotting Factors

Interaction of the Fibrinolytic, Coagulation, and Kinin Systems; Disseminated Intravascular Coagulation; and Related Pathology

Introduction to Thrombosis and Anticoagulant Therapy

Quality Control in the Hematology Laboratory

Body Fluid Examination: the Qualitative, Quantitative, and Morphologic Analysis of Serous, Cerebrospinal, and Synovial Fluids

Hematology Methods

Principles of Automated Differential Analysis

Coagulation Procedures

Applications of Flow Cytometry to Hematology and Hemostasis

Molecular Diagnostic Techniques in Hematopathology

Special Stainscytochemistry

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