Exam 13: Gene Expression

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What evolutionary role is served by the redundancy of the genetic code?

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In the Beadle and Tatum study, it was important that Neurospora was haploid because:

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Figure 13-3 Figure 13-3   Refer to the accompanying figure. Which label indicates the location of the promoter region? Refer to the accompanying figure. Which label indicates the location of the promoter region?

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These noncoding sequences located within coding regions of ____ genes are called ____.

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Beadle and Tatum began their studies with wild-type Neurospora. How is this organism best characterized?

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Leader sequences contain signals that:

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The 3' trailing sequences are located upstream of the stop codon. __________________

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Reverse transcriptase catalyzes the synthesis of DNA from an RNA template. __________________

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Following peptide bond formation between the amino acid in the A site on the ribosome and the growing polypeptide chain, the tRNA in the A site:

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Figure 13-2 Figure 13-2   Refer to the accompanying figure. The portion of the molecule labeled as 5 is: Refer to the accompanying figure. The portion of the molecule labeled as 5 is:

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Match the event to the correct process of protein synthesis.
growth of the polypeptide chain
elongation
the first stage of translation
initiation
triggered by a stop codon
termination
Correct Answer:
Verified
Premises:
Responses:
growth of the polypeptide chain
elongation
the first stage of translation
initiation
triggered by a stop codon
termination
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Eukaryotic mRNA has a significantly longer half life than its prokaryotic counterpart. How is this accomplished in eukaryotes? What processes tend to degrade mRNA molecules in both eukaryotes and prokaryotes, and why are these processes needed?

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If an mRNA transcript of the human XYZ gene was introduced into a yeast cell, the transcript would be:

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How is the four-letter language of nucleic acids converted into the twenty-word language of amino acids?

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Match the RNA molecule with its corresponding description.
small double-stranded RNA molecules; regulates gene expression
SRP RNA
large RNA molecules; regulates chromatin structure
miRNA
small RNA molecules; inhibits mobile DNA element activity in germ cells
snoRNA
Correct Answer:
Verified
Premises:
Responses:
small double-stranded RNA molecules; regulates gene expression
SRP RNA
large RNA molecules; regulates chromatin structure
miRNA
small RNA molecules; inhibits mobile DNA element activity in germ cells
snoRNA
small RNA molecules; inhibit translation
siRNA
helps to deliver the ribosome-mRNA-polypeptide complex to the rough ER
lncRNA
responsible for pre-rRNA molecule processing in the nucleolus
piRNA
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snRNPs function to splice introns together. __________________

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A polyribosome is:

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Draw a general overview of the flow of genetic information from DNA to protein in eukaryote vs. prokarytotes. You should construct one drawing for eukaryotes and one for prokaryotes. Label all structures, molecules, processes, and cellular compartments.

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RNA polymerase binds to the promoter sequence in RNA . __________________

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Discuss which type of DNA mutation in the coding region of an essential human gene (for example, insulin) would be the most harmful to a phenotype. Consider missense, nonsense, frameshifts, and transposons.

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