Question 1

What adult phenotype is rich in i antigen and common to the white population?

Accepted Answer

A)  I1 
B)  I2 
C)  i1 
D)  i2 
A)  I1 
B)  I2 
C)  i1 
D)  i2

Question 2

Anti-i is found in association with what disease?

Accepted Answer

A)  Pneumonia 
B)  Infectious mononucleosis 
C)  Syphilis 
D)  Gonorrhea 
A)  Pneumonia 
B)  Infectious mononucleosis 
C)  Syphilis 
D)  Gonorrhea

Question 3

Autoantibodies to Jka have been found in patients taking:

Accepted Answer

A)  ibuprofen. 
B)  penicillin. 
C)  methyldopa. 
D)  none of the above. 
A)  ibuprofen. 
B)  penicillin. 
C)  methyldopa. 
D)  none of the above.

Question 4

A patient was phenotyped for the presence of Lewis antigens (Lea and Leb). A 3+ reaction was observed when patient cells were incubated with anti-Lea. No reaction was observed with anti-Leb. Based on these results, the patient's phenotype is and the patient is a of ABH substances.

Accepted Answer

A)  Le(a+b-)/secretor 
B)  Le(a-b+)/secretor 
C)  Le(a+b-)/nonsecretor 
D)  Le(a-b+)/nonsecretor 
A)  Le(a+b-)/secretor 
B)  Le(a-b+)/secretor 
C)  Le(a+b-)/nonsecretor 
D)  Le(a-b+)/nonsecretor

Question 5

Why is it relatively easy to find compatible units for a patient with anti-K?

Accepted Answer

A)  Kell is a low-frequency antigen. 
B)  Kell is a high-frequency antigen. 
C)  Anti-K does not react at 37°C. 
D)  Anti-K has a low avidity for its respective antigen. 
A)  Kell is a low-frequency antigen. 
B)  Kell is a high-frequency antigen. 
C)  Anti-K does not react at 37°C. 
D)  Anti-K has a low avidity for its respective antigen.

Question 6

Which of the following is TRUE concerning the I and i antigens?

Accepted Answer

A)  I and i antigens are antithetical. 
B)  I and i antigens have a reciprocal relationship. 
C)  Adult RBCs i antigen positive and I antigen negative. 
D)  Infant's RBCs convert from I to i antigen in 18 months. 
A)  I and i antigens are antithetical. 
B)  I and i antigens have a reciprocal relationship. 
C)  Adult RBCs i antigen positive and I antigen negative. 
D)  Infant's RBCs convert from I to i antigen in 18 months.

Question 7

The true Lewis phenotype will normally be detected at what age?

Accepted Answer

A)  Birth 
B)  10 days 
C)  6 years 
D)  Not necessarily ever, as circumstances such as pregnancy may alter or mask an individual's true Lewis phenotype 
A)  Birth 
B)  10 days 
C)  6 years 
D)  Not necessarily ever, as circumstances such as pregnancy may alter or mask an individual's true Lewis phenotype

Question 8

Anti-Anton recognizes the same specificity as:

Accepted Answer

A)  anti-Wj. 
B)  anti-Aua. 
C)  anti-Lu3. 
D)  anti-Lub. 
A)  anti-Wj. 
B)  anti-Aua. 
C)  anti-Lu3. 
D)  anti-Lub.

Question 9

What organism is capable of converting Jk(b-) red blood cells to Jk(b+)?

Accepted Answer

A)  Escherichia coli 
B)  Micrococcus species 
C)  Proteus vulgaris 
D)  Streptococcus pneumoniae 
A)  Escherichia coli 
B)  Micrococcus species 
C)  Proteus vulgaris 
D)  Streptococcus pneumoniae

Question 10

A person who inherits the In(Lu) gene will not express which antigens?

Accepted Answer

A)  Lua 
B)  K 
C)  c 
D)  S 
A)  Lua 
B)  K 
C)  c 
D)  S

Question 11

Pregnant women usually express which phenotype?

Accepted Answer

A)  Le(a+b-) 
B)  Le(a+b+) 
C)  Le(a-b-) 
D)  Le(a-b+) 
A)  Le(a+b-) 
B)  Le(a+b+) 
C)  Le(a-b-) 
D)  Le(a-b+)

Question 12

All of the following are characteristics of Duffy antibodies except:

Accepted Answer

A)  they are IgG in nature. 
B)  they may or may not show dosage. 
C)  they are destroyed by enzymes. 
D)  they are not implicated in HDN. 
A)  they are IgG in nature. 
B)  they may or may not show dosage. 
C)  they are destroyed by enzymes. 
D)  they are not implicated in HDN.

Question 13

What is Kell's antithetical partner?

Accepted Answer

A)  Penney 
B)  Cellano 
C)  Sutter 
D)  Rautenberg 
A)  Penney 
B)  Cellano 
C)  Sutter 
D)  Rautenberg

Question 14

What biochemical substituent is responsible for the i determinant?

Accepted Answer

A)  Two repeating N-acetyllactosamine units on H3 structures 
B)  Two repeating N-acetyllactosamine units on H4 structures 
C)  Two repeating N-acetyllactosamine units on H2 structures 
D)  Two repeating N-acetyllactosamine units on H1 structures 
A)  Two repeating N-acetyllactosamine units on H3 structures 
B)  Two repeating N-acetyllactosamine units on H4 structures 
C)  Two repeating N-acetyllactosamine units on H2 structures 
D)  Two repeating N-acetyllactosamine units on H1 structures

Question 15

Which enzyme is responsible for Lewis specificity?

Accepted Answer

A)  L-fucosyltransferase 
B)  N-acetylglycosyltransferase 
C)  D-galactosyltransferase 
D)  N-acetylgalactosyltransferase 
A)  L-fucosyltransferase 
B)  N-acetylglycosyltransferase 
C)  D-galactosyltransferase 
D)  N-acetylgalactosyltransferase

Question 16

What biochemical observations signify a protein composition to the Kell antigens?

Accepted Answer

A)  Degradation with formaldehyde 
B)  Inactivation at 56°C 
C)  Cell-membrane orientation 
D)  None of the above 
A)  Degradation with formaldehyde 
B)  Inactivation at 56°C 
C)  Cell-membrane orientation 
D)  None of the above

Question 17

Persons with the Kidd-null phenotype have been found in:

Accepted Answer

A)  Russia. 
B)  New Zealand. 
C)  North America. 
D)  Saudi Arabia. 
A)  Russia. 
B)  New Zealand. 
C)  North America. 
D)  Saudi Arabia.

Question 18

Anti-Lua reacts at what temperature?

Accepted Answer

A)  Room temperature 
B)  37°C 
C)  AHG 
D)  All of the above 
A)  Room temperature 
B)  37°C 
C)  AHG 
D)  All of the above

Question 19

How were Aua and Aub initially linked to the Lutheran system?

Accepted Answer

A)  Enhanced by enzymes (trysin) 
B)  Well-expressed on cord cells 
C)  Suppression by In(Lu) gene 
D)  Antigens active on H precursor substance 
A)  Enhanced by enzymes (trysin) 
B)  Well-expressed on cord cells 
C)  Suppression by In(Lu) gene 
D)  Antigens active on H precursor substance

Question 20

Where are the P antigens found?

Accepted Answer

A)  Red blood cells 
B)  Platelets 
C)  Tissue fibroblasts 
D)  All of the above 
A)  Red blood cells 
B)  Platelets 
C)  Tissue fibroblasts 
D)  All of the above

Exam 8: Blood Group Terminology and Common Blood Groups

What adult phenotype is rich in i antigen and common to the white population?

Anti-i is found in association with what disease?

Autoantibodies to Jka have been found in patients taking:

A patient was phenotyped for the presence of Lewis antigens (Lea and Leb). A 3+ reaction was observed when patient cells were incubated with anti-Lea. No reaction was observed with anti-Leb. Based on these results, the patient's phenotype is and the patient is a of ABH substances.

Why is it relatively easy to find compatible units for a patient with anti-K?

Which of the following is TRUE concerning the I and i antigens?

The true Lewis phenotype will normally be detected at what age?

Anti-Anton recognizes the same specificity as:

What organism is capable of converting Jk(b-) red blood cells to Jk(b+)?

A person who inherits the In(Lu) gene will not express which antigens?

Pregnant women usually express which phenotype?

All of the following are characteristics of Duffy antibodies except:

What is Kell's antithetical partner?

What biochemical substituent is responsible for the i determinant?

Which enzyme is responsible for Lewis specificity?

What biochemical observations signify a protein composition to the Kell antigens?

Persons with the Kidd-null phenotype have been found in:

Anti-Lua reacts at what temperature?

How were Aua and Aub initially linked to the Lutheran system?

Where are the P antigens found?

Red Blood Cells and Platelet Preservation: Historical Perspectives and Current Trends

Basic Genetics

Fundamentals of Immunology

Concepts in Molecular Biology

The Antiglobulin Test

The Abo Blood Group System

The Rh Blood Group System

Uncommon Blood Groups

Detection and Identification of Antibodies

Pre-Transfusion Testing

Blood Bank Technologies and Automation

Donor Selection

Transfusion-Transmitted Diseases

Component Preparation

Transfusion Therapy

Adverse Effects of Blood Transfusion

Apheresis

Cellular Therapy in the Transplant Setting

Hemolytic Disease of the Fetus and Newborn

Autoimmune Hemolytic Anemias

Tissue Banking As Part of the Transfusion Service

The Hla System

Relationship Testing

Quality Management

Patient Blood Management

Transfusion Safety and Federal Regulatory Requirements

Laboratory Information Systems in the Blood Bank

Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services

Filters

Autoantibodies to Jk^a have been found in patients taking:

A patient was phenotyped for the presence of Lewis antigens (Le^a and Le^b). A 3+ reaction was observed when patient cells were incubated with anti-Le^a. No reaction was observed with anti-Le^b. Based on these results, the patient's phenotype is and the patient is a of ABH substances.

Anti-Lu^a reacts at what temperature?

How were Au^a and Au^b initially linked to the Lutheran system?