Question 1

Both anti-Dia and anti-Dib are known to:

Accepted Answer

A)  cause severe HDN. 
B)  bind complement. 
C)  occur as a result of red blood cell stimulation. 
D)  react at the 37°C and IgG phases. 
A)  cause severe HDN. 
B)  bind complement. 
C)  occur as a result of red blood cell stimulation. 
D)  react at the 37°C and IgG phases. C

Question 2

Which population is most likely to exhibit the Di(b-) phenotype?

Accepted Answer

A)  Central America 
B)  Native Americans 
C)  South America 
D)  All of these 
A)  Central America 
B)  Native Americans 
C)  South America 
D)  All of these D

Question 3

Which antigen is expressed on C4B complement fragments?

Accepted Answer

A)  Cha 
B)  Kna 
C)  Yka 
D)  Gya 
A)  Cha 
B)  Kna 
C)  Yka 
D)  Gya A

Question 4

Which antibody is enhanced with enzymes?

Accepted Answer

A)  Colton 
B)  Gill 
C)  Forssman 
D)  All of these 
A)  Colton 
B)  Gill 
C)  Forssman 
D)  All of these

Question 5

Which of these is the Gerbich null phenotype?

Accepted Answer

A)  Gerbich 
B)  Leach 
C)  Yus 
D)  None of these 
A)  Gerbich 
B)  Leach 
C)  Yus 
D)  None of these

Question 6

The following is true regarding anti-Doa and anti-Dob.

Accepted Answer

A)  They are destroyed by enzymes. 
B)  They are frequently naturally occurring. 
C)  They are known to cause HTRs. 
D)  They are known to cause clinical HDN. 
A)  They are destroyed by enzymes. 
B)  They are frequently naturally occurring. 
C)  They are known to cause HTRs. 
D)  They are known to cause clinical HDN.

Question 7

What percentage of the female population is Xg(a+)?

Accepted Answer

A)  50% 
B)  66% 
C)  89% 
D)  40% 
A)  50% 
B)  66% 
C)  89% 
D)  40%

Question 8

Which statement is true concerning the Cartwright antigens?

Accepted Answer

A)  The Ytb antigen is a strong immunogen. 
B)  Cord blood tests as Yta negative. 
C)  The Yta is inherited as a dominant allele. 
D)  Ytb is a high-frequency antigen. 
A)  The Ytb antigen is a strong immunogen. 
B)  Cord blood tests as Yta negative. 
C)  The Yta is inherited as a dominant allele. 
D)  Ytb is a high-frequency antigen.

Question 9

Which statement describes the role of Knops (CR1) in immunity?

Accepted Answer

A)  CR1 binds the complement component fragments C3b and C4b. 
B)  CR1 functions as a receptor for several pathogenic organisms. 
C)  CR1 processes immune complexes for transportation to the liver and spleen. 
D)  CR1 performs all these roles. 
A)  CR1 binds the complement component fragments C3b and C4b. 
B)  CR1 functions as a receptor for several pathogenic organisms. 
C)  CR1 processes immune complexes for transportation to the liver and spleen. 
D)  CR1 performs all these roles.

Question 10

Haemophilus influenza is able to gain entry in to red blood cells via which antigen?

Accepted Answer

A)  Anton 
B)  Emm 
C)  Sid 
D)  Vel 
A)  Anton 
B)  Emm 
C)  Sid 
D)  Vel

Question 11

Gy(a-) RBCs are also

Accepted Answer

A)  Do(a-b-). 
B)  Do(a-b+). 
C)  Do(a+b-). 
D)  Do(a+b+). 
A)  Do(a-b-). 
B)  Do(a-b+). 
C)  Do(a+b-). 
D)  Do(a+b+).

Question 12

Which antigen is associated with Dombrock null?

Accepted Answer

A)  Gy 
B)  Hy 
C)  Jo 
D)  None of these 
A)  Gy 
B)  Hy 
C)  Jo 
D)  None of these

Question 13

In testing blood cells for the Knops antigen, which would most likely be positive?

Accepted Answer

A)  Cord blood 
B)  Fresh units from Caucasians 
C)  Fresh units from West Africans 
D)  Older units from any population 
A)  Cord blood 
B)  Fresh units from Caucasians 
C)  Fresh units from West Africans 
D)  Older units from any population

Question 14

The gene for which blood group antigen is located on the petite arm of the X chromosome?

Accepted Answer

A)  Sc1 
B)  Xga 
C)  Coa 
D)  Doa 
A)  Sc1 
B)  Xga 
C)  Coa 
D)  Doa

Question 15

What criteria must be met for an antigen to be assigned to a blood group system?

Accepted Answer

A)  Must be a red blood cell antigen 
B)  Must be assigned to a unique chromosomal locus 
C)  Must be controlled by a single gene or two closely linked genes 
D)  All of the above 
A)  Must be a red blood cell antigen 
B)  Must be assigned to a unique chromosomal locus 
C)  Must be controlled by a single gene or two closely linked genes 
D)  All of the above

Question 16

Which antigen in the high-incidence series (901) is usually IgM and occasionally causes hemolysis?

Accepted Answer

A)  Vel 
B)  JMH 
C)  Lan 
D)  Sda 
A)  Vel 
B)  JMH 
C)  Lan 
D)  Sda

Question 17

Anti-Sc3 will react with which Scianna phenotype?

Accepted Answer

A)  Sc: -1, +2 
B)  Sc: +1, +2 
C)  Sc: +1, -2 
D)  All of the above 
A)  Sc: -1, +2 
B)  Sc: +1, +2 
C)  Sc: +1, -2 
D)  All of the above

Question 18

Anti-Lan is able to cause

Accepted Answer

A)  Severe hemolytic transfusion reactions. 
B)  Hemolytic disease of the fetus and newborn. 
C)  Both of these 
D)  Neither of these. 
A)  Severe hemolytic transfusion reactions. 
B)  Hemolytic disease of the fetus and newborn. 
C)  Both of these 
D)  Neither of these.

Question 19

Which of the following is true concerning Colton antibodies?

Accepted Answer

A)  Encountered frequently 
B)  Destroyed by enzymes 
C)  React at immediate spin 
D)  Stimulated by red blood cell exposure 
A)  Encountered frequently 
B)  Destroyed by enzymes 
C)  React at immediate spin 
D)  Stimulated by red blood cell exposure

Question 20

Anti-Wrb has been frequently observed in patients:

Accepted Answer

A)  with paroxysmal cold hemoglobinuria. 
B)  with warm autoimmune hemolytic anemia. 
C)  taking penicillin. 
D)  with paroxysmal nocturnal hemoglobinuria. 
A)  with paroxysmal cold hemoglobinuria. 
B)  with warm autoimmune hemolytic anemia. 
C)  taking penicillin. 
D)  with paroxysmal nocturnal hemoglobinuria.

Exam 9: Uncommon Blood Groups

Both anti-Dia and anti-Dib are known to:

Which population is most likely to exhibit the Di(b-) phenotype?

Which antigen is expressed on C4B complement fragments?

Which antibody is enhanced with enzymes?

Which of these is the Gerbich null phenotype?

The following is true regarding anti-Doa and anti-Dob.

What percentage of the female population is Xg(a+)?

Which statement is true concerning the Cartwright antigens?

Which statement describes the role of Knops (CR1) in immunity?

Haemophilus influenza is able to gain entry in to red blood cells via which antigen?

Gy(a-) RBCs are also

Which antigen is associated with Dombrock null?

In testing blood cells for the Knops antigen, which would most likely be positive?

The gene for which blood group antigen is located on the petite arm of the X chromosome?

What criteria must be met for an antigen to be assigned to a blood group system?

Which antigen in the high-incidence series (901) is usually IgM and occasionally causes hemolysis?

Anti-Sc3 will react with which Scianna phenotype?

Anti-Lan is able to cause

Which of the following is true concerning Colton antibodies?

Anti-Wrb has been frequently observed in patients:

Red Blood Cells and Platelet Preservation: Historical Perspectives and Current Trends

Basic Genetics

Fundamentals of Immunology

Concepts in Molecular Biology

The Antiglobulin Test

The Abo Blood Group System

The Rh Blood Group System

Blood Group Terminology and Common Blood Groups

Detection and Identification of Antibodies

Pre-Transfusion Testing

Blood Bank Technologies and Automation

Donor Selection

Transfusion-Transmitted Diseases

Component Preparation

Transfusion Therapy

Adverse Effects of Blood Transfusion

Apheresis

Cellular Therapy in the Transplant Setting

Hemolytic Disease of the Fetus and Newborn

Autoimmune Hemolytic Anemias

Tissue Banking As Part of the Transfusion Service

The Hla System

Relationship Testing

Quality Management

Patient Blood Management

Transfusion Safety and Federal Regulatory Requirements

Laboratory Information Systems in the Blood Bank

Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services

Filters

Both anti-Di^a and anti-Di^b are known to:

Which antigen is expressed on C₄B complement fragments?

The following is true regarding anti-Do^a and anti-Do^b.

Anti-Wr^b has been frequently observed in patients: