Question 1

Each cryoprecipitate unit contains at least how much factor VIII?

Accepted Answer

A)  80 units 
B)  50 units 
C)  30 units 
D)  100 units 
A)  80 units 
B)  50 units 
C)  30 units 
D)  100 units A

Question 2

Cryoprecipitated AHF can be used in the treatment of:

Accepted Answer

A)  Bernard-Soulier syndrome. 
B)  von Willebrand's disease (vW
D) . 
C)  antithrombin III deficiency. 
D)  hemolytic uremic syndrome. 
A)  Bernard-Soulier syndrome. 
B)  von Willebrand's disease (vW
D) . 
C)  antithrombin III deficiency. 
D)  hemolytic uremic syndrome. B

Question 3

What is the expiration on washed red blood cells?

Accepted Answer

A)  35 days 
B)  24 hours 
C)  42 days 
D)  6 hours 
A)  35 days 
B)  24 hours 
C)  42 days 
D)  6 hours B

Question 4

What is the most efficient way to remove leukocytes from red blood cell units?

Accepted Answer

A)  Leukoreduction filters 
B)  Centrifugation 
C)  Deglycerolizing 
D)  Washing 
A)  Leukoreduction filters 
B)  Centrifugation 
C)  Deglycerolizing 
D)  Washing

Question 5

Which of the following should be done when selecting units for a hypoxic neonate?

Accepted Answer

A)  Irradiation 
B)  Cytomegalovirus testing 
C)  Hgb S testing 
D)  Epstein-Barr virus testing 
A)  Irradiation 
B)  Cytomegalovirus testing 
C)  Hgb S testing 
D)  Epstein-Barr virus testing

Question 6

Which blood product is used in the treatment of DIC?

Accepted Answer

A)  Plasma 
B)  Platelets 
C)  Cryoprecipitate 
D)  All of the above 
A)  Plasma 
B)  Platelets 
C)  Cryoprecipitate 
D)  All of the above

Question 7

Which of the following statements concerning red blood cells prepared with additive solution 1 (AS-1) is true?

Accepted Answer

A)  The shelf life is 35 days. 
B)  The AS-1 unit contains more plasma than the CPDA-1 red blood cells. 
C)  Red blood cell mass is lower than that of CPDA-1 red blood cells. 
D)  The hematocrit is lower than CPDA-1 red blood cells. 
A)  The shelf life is 35 days. 
B)  The AS-1 unit contains more plasma than the CPDA-1 red blood cells. 
C)  Red blood cell mass is lower than that of CPDA-1 red blood cells. 
D)  The hematocrit is lower than CPDA-1 red blood cells.

Question 8

What is the recommended treatment for mild von Willebrand's disease?

Accepted Answer

A)  VIII concentrate 
B)  Fresh frozen plasma 
C)  Cryoprecipitate 
D)  DDAVP (1-Deamino-8-arginine vasopressin) 
A)  VIII concentrate 
B)  Fresh frozen plasma 
C)  Cryoprecipitate 
D)  DDAVP (1-Deamino-8-arginine vasopressin)

Question 9

A blood component should be transfused within:

Accepted Answer

A)  1 hour. 
B)  2 hours. 
C)  3 hours. 
D)  4 hours. 
A)  1 hour. 
B)  2 hours. 
C)  3 hours. 
D)  4 hours.

Question 10

The rejection of platelets in multiply transfused patients is called:

Accepted Answer

A)  platelet satellitism. 
B)  stimulation. 
C)  refractoriness. 
D)  urticaria. 
A)  platelet satellitism. 
B)  stimulation. 
C)  refractoriness. 
D)  urticaria.

Question 11

Which of the following are not at risk for developing cytomegalovirus (CMV) via CMV-positive blood products?

Accepted Answer

A)  CMV-positive heart transplant recipients 
B)  CMV-negative pregnant women 
C)  CMV-negative bone marrow transplant recipients 
D)  CMV-negative premature infants 
A)  CMV-positive heart transplant recipients 
B)  CMV-negative pregnant women 
C)  CMV-negative bone marrow transplant recipients 
D)  CMV-negative premature infants

Question 12

Which type of autologous transfusion, successful in liver transplants, involves collecting 1 to 2 units from the patient before surgery, using crystalloid to replace blood volume and reinfusing blood at the end of surgery?

Accepted Answer

A)  Intraoperative hemodilution 
B)  Predeposit donation 
C)  Intraoperative salvage 
D)  Postoperative salvage 
A)  Intraoperative hemodilution 
B)  Predeposit donation 
C)  Intraoperative salvage 
D)  Postoperative salvage

Question 13

What blood component is responsible for most allergic reactions?

Accepted Answer

A)  Platelets 
B)  Plasma 
C)  Red blood cells 
D)  White blood cells 
A)  Platelets 
B)  Plasma 
C)  Red blood cells 
D)  White blood cells

Question 14

Why is plasma not recommended for the treatment of hemophilia B?

Accepted Answer

A)  Hypervolemia limits factor IX efficacy. 
B)  Hypovolemia limits factor IX efficacy. 
C)  Plasma is devoid of factor IX. 
D)  None of the above 
A)  Hypervolemia limits factor IX efficacy. 
B)  Hypovolemia limits factor IX efficacy. 
C)  Plasma is devoid of factor IX. 
D)  None of the above

Question 15

Four units of packed RBCs were used in the operating room at 3 p.m. Can the remaining 2 units be returned to the blood bank at 5 p.m.?

Accepted Answer

A)  Yes, if the 2 units have been kept under the proper storage conditions 
B)  Yes, but only if the units are to be used for the same patient 
C)  No, units may have been out of blood bank for more than 4 hours 
D)  No, units have been out of the blood bank for longer than 30 minutes 
A)  Yes, if the 2 units have been kept under the proper storage conditions 
B)  Yes, but only if the units are to be used for the same patient 
C)  No, units may have been out of blood bank for more than 4 hours 
D)  No, units have been out of the blood bank for longer than 30 minutes

Question 16

Persons making predeposit donations for planned surgery will take iron supplements to replenish iron and stimulate:

Accepted Answer

A)  myelopoiesis. 
B)  erythropoiesis. 
C)  thrombopoiesis. 
D)  lymphopoiesis. 
A)  myelopoiesis. 
B)  erythropoiesis. 
C)  thrombopoiesis. 
D)  lymphopoiesis.

Question 17

Which class of vWD provides the least amount of vWF?

Accepted Answer

A)  Type I 
B)  Type IIB 
C)  Type III 
D)  Type IIA 
A)  Type I 
B)  Type IIB 
C)  Type III 
D)  Type IIA

Question 18

What is the source of hyperimmune globulins used in the prevention of hepatitis B?

Accepted Answer

A)  Recombinant hepatitis B purified protein 
B)  Plasma donors whose sera are devoid of hepatitis B antibody 
C)  Plasma donors whose sera demonstrate a high titer of hepatitis B antibody 
D)  None of the above 
A)  Recombinant hepatitis B purified protein 
B)  Plasma donors whose sera are devoid of hepatitis B antibody 
C)  Plasma donors whose sera demonstrate a high titer of hepatitis B antibody 
D)  None of the above

Question 19

A patient with paroxysmal cold hemoglobinuria (PCH) would requirein the event of a blood transfusion.

Accepted Answer

A)  irradiation 
B)  cytomegalovirus-negative units 
C)  a blood warmer 
D)  Hgb S-negative units 
A)  irradiation 
B)  cytomegalovirus-negative units 
C)  a blood warmer 
D)  Hgb S-negative units

Question 20

In addition to nonhemolytic febrile transfusion reactions, what other indication exists for washed red blood cells?

Accepted Answer

A)  IgM-deficient patients with anti-IgM 
B)  IgE-deficient patients with anti-IgE 
C)  IgA-deficient patients with anti-IgA 
D)  IgG-deficient patients with anti-IgG 
A)  IgM-deficient patients with anti-IgM 
B)  IgE-deficient patients with anti-IgE 
C)  IgA-deficient patients with anti-IgA 
D)  IgG-deficient patients with anti-IgG

Exam 16: Transfusion Therapy

Each cryoprecipitate unit contains at least how much factor VIII?

Cryoprecipitated AHF can be used in the treatment of:

What is the expiration on washed red blood cells?

What is the most efficient way to remove leukocytes from red blood cell units?

Which of the following should be done when selecting units for a hypoxic neonate?

Which blood product is used in the treatment of DIC?

Which of the following statements concerning red blood cells prepared with additive solution 1 (AS-1) is true?

What is the recommended treatment for mild von Willebrand's disease?

A blood component should be transfused within:

The rejection of platelets in multiply transfused patients is called:

Which of the following are not at risk for developing cytomegalovirus (CMV) via CMV-positive blood products?

Which type of autologous transfusion, successful in liver transplants, involves collecting 1 to 2 units from the patient before surgery, using crystalloid to replace blood volume and reinfusing blood at the end of surgery?

What blood component is responsible for most allergic reactions?

Why is plasma not recommended for the treatment of hemophilia B?

Four units of packed RBCs were used in the operating room at 3 p.m. Can the remaining 2 units be returned to the blood bank at 5 p.m.?

Persons making predeposit donations for planned surgery will take iron supplements to replenish iron and stimulate:

Which class of vWD provides the least amount of vWF?

What is the source of hyperimmune globulins used in the prevention of hepatitis B?

A patient with paroxysmal cold hemoglobinuria (PCH) would requirein the event of a blood transfusion.

In addition to nonhemolytic febrile transfusion reactions, what other indication exists for washed red blood cells?

Red Blood Cells and Platelet Preservation: Historical Perspectives and Current Trends

Basic Genetics

Fundamentals of Immunology

Concepts in Molecular Biology

The Antiglobulin Test

The Abo Blood Group System

The Rh Blood Group System

Blood Group Terminology and Common Blood Groups

Uncommon Blood Groups

Detection and Identification of Antibodies

Pre-Transfusion Testing

Blood Bank Technologies and Automation

Donor Selection

Transfusion-Transmitted Diseases

Component Preparation

Adverse Effects of Blood Transfusion

Apheresis

Cellular Therapy in the Transplant Setting

Hemolytic Disease of the Fetus and Newborn

Autoimmune Hemolytic Anemias

Tissue Banking As Part of the Transfusion Service

The Hla System

Relationship Testing

Quality Management

Patient Blood Management

Transfusion Safety and Federal Regulatory Requirements

Laboratory Information Systems in the Blood Bank

Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services

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