Question 1

A child undergoing apheresis may require CFC to minimize:

Accepted Answer

A)  extracorporeal volume. 
B)  extravascular volume. 
C)  intracorporeal volume. 
D)  extramedullary volume. 
A)  extracorporeal volume. 
B)  extravascular volume. 
C)  intracorporeal volume. 
D)  extramedullary volume. A

Question 2

While undergoing plasmapheresis, the donor experienced numbness around his mouth, which is indicative of citrate toxicity. How can this be treated?

Accepted Answer

A)  Administering exogenous sodium 
B)  Administering exogenous potassium 
C)  Administering exogenous calcium 
D)  Decreasing the extracorporeal volume 
A)  Administering exogenous sodium 
B)  Administering exogenous potassium 
C)  Administering exogenous calcium 
D)  Decreasing the extracorporeal volume C

Question 3

All of the following statements are consistent with CFC except:

Accepted Answer

A)  blood is drawn from one phlebotomy site and returned through another. 
B)  reinfusion to the patient completes one cycle. 
C)  the process of phlebotomy, separation, and reinfusion is uninterrupted. 
D)  separation of components is achieved through centrifugation. 
A)  blood is drawn from one phlebotomy site and returned through another. 
B)  reinfusion to the patient completes one cycle. 
C)  the process of phlebotomy, separation, and reinfusion is uninterrupted. 
D)  separation of components is achieved through centrifugation. B

Question 4

The removal of granulocytic cells from patient plasma can be assisted through the use of which adsorbent during plasmapheresis procedures?

Accepted Answer

A)  Cellulose acetate 
B)  Charcoal 
C)  Polymyxin B 
D)  Any of these. 
A)  Cellulose acetate 
B)  Charcoal 
C)  Polymyxin B 
D)  Any of these.

Question 5

All of the following constitute variables of apheresis procedures except:

Accepted Answer

A)  centrifuge speed. 
B)  anticoagulant. 
C)  length of blood dwell time in centrifuge. 
D)  blood type. 
A)  centrifuge speed. 
B)  anticoagulant. 
C)  length of blood dwell time in centrifuge. 
D)  blood type.

Question 6

What effect do steroids have on leukapheresis?

Accepted Answer

A)  Decrease the vascular pool of granulocytes 
B)  Increase the vascular pool of granulocytes 
C)  Help to separate red blood cells from white blood cells, using specific gravity properties 
D)  Neutralize the effect of toxic granulation in neutrophils 
A)  Decrease the vascular pool of granulocytes 
B)  Increase the vascular pool of granulocytes 
C)  Help to separate red blood cells from white blood cells, using specific gravity properties 
D)  Neutralize the effect of toxic granulation in neutrophils

Question 7

Which of the following factors influenced the need for apheresis technology?

Accepted Answer

A)  Marked increase in the number of exchange transfusions 
B)  Amputee patients 
C)  The blood component needs of patients on chemotherapy 
D)  AIDS epidemic 
A)  Marked increase in the number of exchange transfusions 
B)  Amputee patients 
C)  The blood component needs of patients on chemotherapy 
D)  AIDS epidemic

Question 8

What effect does aspirin have on platelets?

Accepted Answer

A)  Prevents release of ATP 
B)  Prevents platelet adhesion 
C)  Prevents platelet aggregation 
D)  Inhibits antigen expression 
A)  Prevents release of ATP 
B)  Prevents platelet adhesion 
C)  Prevents platelet aggregation 
D)  Inhibits antigen expression

Question 9

Erythrocytapheresis is successful in which of the following conditions?

Accepted Answer

A)  Leukemia 
B)  Colon/rectal cancer 
C)  Malaria 
D)  Waldenstrom's macroglobulinemia 
A)  Leukemia 
B)  Colon/rectal cancer 
C)  Malaria 
D)  Waldenstrom's macroglobulinemia

Question 10

What is therapeutic plasmapheresis?

Accepted Answer

A)  The removal of large volumes of patient plasma 
B)  The removal of minute volumes of patient plasma 
C)  The removal of plasma containing anti-D 
D)  The removal of plasma containing immunoglobulin 
A)  The removal of large volumes of patient plasma 
B)  The removal of minute volumes of patient plasma 
C)  The removal of plasma containing anti-D 
D)  The removal of plasma containing immunoglobulin

Question 11

During a plasmapheresis procedure, the red blood cells must be returned within how many hours of phlebotomy?

Accepted Answer

A)  2 hours 
B)  4 hours 
C)  6 hours 
D)  8 hours 
A)  2 hours 
B)  4 hours 
C)  6 hours 
D)  8 hours

Question 12

The removal of bile acids from patient plasma can be assisted through the use of which adsorbent during plasmapheresis procedures?

Accepted Answer

A)  Cellulose acetate 
B)  Charcoal 
C)  Polymyxin B 
D)  Any of these. 
A)  Cellulose acetate 
B)  Charcoal 
C)  Polymyxin B 
D)  Any of these.

Question 13

A normal healthy donor undergoes a procedure to obtain platelets that will be transfused to a patient is representative of:

Accepted Answer

A)  therapeutic apheresis collection. 
B)  component apheresis collection. 
C)  whole blood donation. 
D)  None of the above. 
A)  therapeutic apheresis collection. 
B)  component apheresis collection. 
C)  whole blood donation. 
D)  None of the above.

Question 14

In plateletpheresis, which blood component is returned to the donor?

Accepted Answer

A)  Red blood cells 
B)  Platelets 
C)  White blood cells 
D)  Options A and C 
A)  Red blood cells 
B)  Platelets 
C)  White blood cells 
D)  Options A and C

Question 15

Fatalities that result from therapeutic apheresis have primarily been caused by:

Accepted Answer

A)  cardiac arrest and arrhythmia. 
B)  stroke. 
C)  seizure. 
D)  renal failure. 
A)  cardiac arrest and arrhythmia. 
B)  stroke. 
C)  seizure. 
D)  renal failure.

Question 16

Citrate used as an anticoagulant in apheresis procedures is removed from the body by:

Accepted Answer

A)  the kidneys. 
B)  being metabolized in the liver. 
C)  sweating. 
D)  none of the above. 
A)  the kidneys. 
B)  being metabolized in the liver. 
C)  sweating. 
D)  none of the above.

Question 17

Which of the following terms is defined as the removal of white blood cells with the return of red blood cells, plasma, and platelets?

Accepted Answer

A)  Leukapheresis 
B)  Erythrocytapheresis 
C)  Plasmapheresis 
D)  Plateletpheresis 
A)  Leukapheresis 
B)  Erythrocytapheresis 
C)  Plasmapheresis 
D)  Plateletpheresis

Question 18

Which of the following is an indication for therapeutic apheresis?

Accepted Answer

A)  Collection of neocytes to reduce the number of transfusions in patient with thalassemia major 
B)  A pathogenic substance exists in the blood that contributes to a disease process. 
C)  A substance can be more effectively removed by apheresis than by the body's own homeostatic mechanisms. 
D)  Options B and C 
A)  Collection of neocytes to reduce the number of transfusions in patient with thalassemia major 
B)  A pathogenic substance exists in the blood that contributes to a disease process. 
C)  A substance can be more effectively removed by apheresis than by the body's own homeostatic mechanisms. 
D)  Options B and C

Question 19

How is HES used in apheresis procedures?

Accepted Answer

A)  As a chelation agent to bind calcium 
B)  As a sedimenting agent to separate white blood cells from red blood cells 
C)  As a primer to keep infusion lines open 
D)  As a hemolysin to lyse red blood cells 
A)  As a chelation agent to bind calcium 
B)  As a sedimenting agent to separate white blood cells from red blood cells 
C)  As a primer to keep infusion lines open 
D)  As a hemolysin to lyse red blood cells

Question 20

Which apheresis method carries the additional risk of returning red blood cells to the wrong individual and yielding the smallest volume of selected blood component?

Accepted Answer

A)  IFC 
B)  Manual apheresis 
C)  CFC 
D)  Membrane filtration 
A)  IFC 
B)  Manual apheresis 
C)  CFC 
D)  Membrane filtration

Exam 18: Apheresis

A child undergoing apheresis may require CFC to minimize:

While undergoing plasmapheresis, the donor experienced numbness around his mouth, which is indicative of citrate toxicity. How can this be treated?

All of the following statements are consistent with CFC except:

The removal of granulocytic cells from patient plasma can be assisted through the use of which adsorbent during plasmapheresis procedures?

All of the following constitute variables of apheresis procedures except:

What effect do steroids have on leukapheresis?

Which of the following factors influenced the need for apheresis technology?

What effect does aspirin have on platelets?

Erythrocytapheresis is successful in which of the following conditions?

What is therapeutic plasmapheresis?

During a plasmapheresis procedure, the red blood cells must be returned within how many hours of phlebotomy?

The removal of bile acids from patient plasma can be assisted through the use of which adsorbent during plasmapheresis procedures?

A normal healthy donor undergoes a procedure to obtain platelets that will be transfused to a patient is representative of:

In plateletpheresis, which blood component is returned to the donor?

Fatalities that result from therapeutic apheresis have primarily been caused by:

Citrate used as an anticoagulant in apheresis procedures is removed from the body by:

Which of the following terms is defined as the removal of white blood cells with the return of red blood cells, plasma, and platelets?

Which of the following is an indication for therapeutic apheresis?

How is HES used in apheresis procedures?

Which apheresis method carries the additional risk of returning red blood cells to the wrong individual and yielding the smallest volume of selected blood component?

Red Blood Cells and Platelet Preservation: Historical Perspectives and Current Trends

Basic Genetics

Fundamentals of Immunology

Concepts in Molecular Biology

The Antiglobulin Test

The Abo Blood Group System

The Rh Blood Group System

Blood Group Terminology and Common Blood Groups

Uncommon Blood Groups

Detection and Identification of Antibodies

Pre-Transfusion Testing

Blood Bank Technologies and Automation

Donor Selection

Transfusion-Transmitted Diseases

Component Preparation

Transfusion Therapy

Adverse Effects of Blood Transfusion

Cellular Therapy in the Transplant Setting

Hemolytic Disease of the Fetus and Newborn

Autoimmune Hemolytic Anemias

Tissue Banking As Part of the Transfusion Service

The Hla System

Relationship Testing

Quality Management

Patient Blood Management

Transfusion Safety and Federal Regulatory Requirements

Laboratory Information Systems in the Blood Bank

Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services

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