Question 1

What amino acid initiates translation by attaching to tRNA?

Accepted Answer

A)  Glycine 
B)  Alanine 
C)  Methionine 
D)  Lysine 
A)  Glycine 
B)  Alanine 
C)  Methionine 
D)  Lysine C

Question 2

In the MN blood group system, a person who inherits an "M" allele and an "N" allele expresses both M and N antigens on the RBCs. Which of the following is true?

Accepted Answer

A)  M is dominant to N. 
B)  N is dominant to M. 
C)  M an N are codominant alleles. 
D)  M and N are located on the same chromosome. 
A)  M is dominant to N. 
B)  N is dominant to M. 
C)  M an N are codominant alleles. 
D)  M and N are located on the same chromosome. C

Question 3

A woman with blood group A marries a man with blood group O. Their firstborn child has blood group O. The mother's most probable genotype is:

Accepted Answer

A)  OO 
B)  AA 
C)  AB 
D)  AO 
A)  OO 
B)  AA 
C)  AB 
D)  AO D

Question 4

Which constituent in the Hardy-Weinberg equation represents the total number of alleles?

Accepted Answer

A)  q 
B)  p 
C)  2pq 
D)  q2 
A)  q 
B)  p 
C)  2pq 
D)  q2

Question 5

Point mutations include which of the following?

Accepted Answer

A)  Substitutions 
B)  Insertions 
C)  Deletions 
D)  Substitutions, insertions, and deletions 
A)  Substitutions 
B)  Insertions 
C)  Deletions 
D)  Substitutions, insertions, and deletions

Question 6

DNA is composed of all of the following except:

Accepted Answer

A)  adenine. 
B)  guanine. 
C)  cytosine. 
D)  uracil. 
A)  adenine. 
B)  guanine. 
C)  cytosine. 
D)  uracil.

Question 7

Which of the following must be true when using the Hardy-Weinberg equation?

Accepted Answer

A)  The population must be large 
B)  Mutations cannot occur 
C)  Mating must occur randomly 
D)  All of the above 
A)  The population must be large 
B)  Mutations cannot occur 
C)  Mating must occur randomly 
D)  All of the above

Question 8

Which type of genetic change (mutation) is incapable of reverting back to the original phenotype?

Accepted Answer

A)  Duplication 
B)  Deletion 
C)  Recombination 
D)  Insertion 
A)  Duplication 
B)  Deletion 
C)  Recombination 
D)  Insertion

Question 9

Most antigens in the various blood group systems follow what kind of inheritance patterns?

Accepted Answer

A)  Codominant 
B)  Homozygous 
C)  Dominant 
D)  Autosomal 
A)  Codominant 
B)  Homozygous 
C)  Dominant 
D)  Autosomal

Question 10

Alternate forms of a gene that can occur at a single chromosome locus are referred to as:

Accepted Answer

A)  amorphs. 
B)  traits. 
C)  alleles. 
D)  recessive. 
A)  amorphs. 
B)  traits. 
C)  alleles. 
D)  recessive.

Question 11

In a pedigree analysis, what do vertical lines indicate?

Accepted Answer

A)  Consanguineous mating 
B)  Offspring 
C)  Stillbirth 
D)  Deceased sibling 
A)  Consanguineous mating 
B)  Offspring 
C)  Stillbirth 
D)  Deceased sibling

Question 12

How is RNA different from DNA?

Accepted Answer

A)  RNA usually exists as one strand 
B)  Ribose is substituted for deoxyribose 
C)  RNA incorporates uracil 
D)  All of the above 
A)  RNA usually exists as one strand 
B)  Ribose is substituted for deoxyribose 
C)  RNA incorporates uracil 
D)  All of the above

Question 13

A father carries the Xga trait and passes it on to all of his daughters but none of his sons. What type of inheritance does this represent?

Accepted Answer

A)  Autosomal dominant 
B)  X-linked dominant 
C)  X-linked recessive 
D)  Autosomal recessive 
A)  Autosomal dominant 
B)  X-linked dominant 
C)  X-linked recessive 
D)  Autosomal recessive

Question 14

What is a vector?

Accepted Answer

A)  Substance capable of catalyzing a reaction 
B)  Sequence of three bases in a strand of DNA 
C)  Extrachromosomal genetic element that can carry a recombinant DNA molecule into a host bacterial cell 
D)  Substance that can carry an electric current in solution 
A)  Substance capable of catalyzing a reaction 
B)  Sequence of three bases in a strand of DNA 
C)  Extrachromosomal genetic element that can carry a recombinant DNA molecule into a host bacterial cell 
D)  Substance that can carry an electric current in solution

Question 15

In what stage of mitosis is DNA not actively dividing?

Accepted Answer

A)  Interphase 
B)  Prophase 
C)  Metaphase 
D)  Anaphase 
A)  Interphase 
B)  Prophase 
C)  Metaphase 
D)  Anaphase

Question 16

All of the following processes occur in replication, except:

Accepted Answer

A)  the two DNA strands separate via helicase. 
B)  DNA polymerase acts on the 5' to 3' parent strand to produce an anticomplementary duplicate strand. 
C)  DNA polymerase acts on the 3' to 5' parent strand to produce an anticomplementary duplicate strand. 
D)  replication of the 3' to 5' parent strand is initiated by the enzyme primase, which anneals to the parent strand. 
A)  the two DNA strands separate via helicase. 
B)  DNA polymerase acts on the 5' to 3' parent strand to produce an anticomplementary duplicate strand. 
C)  DNA polymerase acts on the 3' to 5' parent strand to produce an anticomplementary duplicate strand. 
D)  replication of the 3' to 5' parent strand is initiated by the enzyme primase, which anneals to the parent strand.

Question 17

All of the following may cause an alteration in DNA, except:

Accepted Answer

A)  ultraviolet light. 
B)  alkylating agents. 
C)  antibodies. 
D)  enzymes. 
A)  ultraviolet light. 
B)  alkylating agents. 
C)  antibodies. 
D)  enzymes.

Question 18

All of the following are consistent with Mendel's basic rules of inheritance except:

Accepted Answer

A)  the gene is transmitted through generations intact. 
B)  a pair of genes is always found in the same gamete. 
C)  different pairs of genes are assorted independently of each other. 
D)  a pair of genes is rarely found in the same gamete. 
A)  the gene is transmitted through generations intact. 
B)  a pair of genes is always found in the same gamete. 
C)  different pairs of genes are assorted independently of each other. 
D)  a pair of genes is rarely found in the same gamete.

Question 19

What is meant by the term autosomal?

Accepted Answer

A)  Trait is not carried on the sex chromosomes 
B)  Trait is carried on sex chromosomes 
C)  Trait is not expressed in the parents 
D)  Organism possesses different alleles for a given characteristic 
A)  Trait is not carried on the sex chromosomes 
B)  Trait is carried on sex chromosomes 
C)  Trait is not expressed in the parents 
D)  Organism possesses different alleles for a given characteristic

Question 20

Methods to isolate intact DNA in order for it to be studied include all of the following except:

Accepted Answer

A)  pH changes. 
B)  enzyme activation. 
C)  detergent lysis. 
D)  heat treatment. 
A)  pH changes. 
B)  enzyme activation. 
C)  detergent lysis. 
D)  heat treatment.

Exam 2: Basic Genetics

What amino acid initiates translation by attaching to tRNA?

In the MN blood group system, a person who inherits an "M" allele and an "N" allele expresses both M and N antigens on the RBCs. Which of the following is true?

A woman with blood group A marries a man with blood group O. Their firstborn child has blood group O. The mother's most probable genotype is:

Which constituent in the Hardy-Weinberg equation represents the total number of alleles?

Point mutations include which of the following?

DNA is composed of all of the following except:

Which of the following must be true when using the Hardy-Weinberg equation?

Which type of genetic change (mutation) is incapable of reverting back to the original phenotype?

Most antigens in the various blood group systems follow what kind of inheritance patterns?

Alternate forms of a gene that can occur at a single chromosome locus are referred to as:

In a pedigree analysis, what do vertical lines indicate?

How is RNA different from DNA?

A father carries the Xga trait and passes it on to all of his daughters but none of his sons. What type of inheritance does this represent?

What is a vector?

In what stage of mitosis is DNA not actively dividing?

All of the following processes occur in replication, except:

All of the following may cause an alteration in DNA, except:

All of the following are consistent with Mendel's basic rules of inheritance except:

What is meant by the term autosomal?

Methods to isolate intact DNA in order for it to be studied include all of the following except:

Red Blood Cells and Platelet Preservation: Historical Perspectives and Current Trends

Fundamentals of Immunology

Concepts in Molecular Biology

The Antiglobulin Test

The Abo Blood Group System

The Rh Blood Group System

Blood Group Terminology and Common Blood Groups

Uncommon Blood Groups

Detection and Identification of Antibodies

Pre-Transfusion Testing

Blood Bank Technologies and Automation

Donor Selection

Transfusion-Transmitted Diseases

Component Preparation

Transfusion Therapy

Adverse Effects of Blood Transfusion

Apheresis

Cellular Therapy in the Transplant Setting

Hemolytic Disease of the Fetus and Newborn

Autoimmune Hemolytic Anemias

Tissue Banking As Part of the Transfusion Service

The Hla System

Relationship Testing

Quality Management

Patient Blood Management

Transfusion Safety and Federal Regulatory Requirements

Laboratory Information Systems in the Blood Bank

Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services

Filters

A father carries the Xg^a trait and passes it on to all of his daughters but none of his sons. What type of inheritance does this represent?