Question 1

Which of the following best describes classical genetics?

Accepted Answer

A)  DNA alteration that is caused by a physical or chemical agent 
B)  Transmission of characteristics from parents to offspring 
C)  Possessing a pair of identical alleles 
D)  The synthesis of RNA from DNA requiring RNA polymerase 
A)  DNA alteration that is caused by a physical or chemical agent 
B)  Transmission of characteristics from parents to offspring 
C)  Possessing a pair of identical alleles 
D)  The synthesis of RNA from DNA requiring RNA polymerase

Question 2

All of the following are included in transcription except:

Accepted Answer

A)  mRNA terminates at the 5' end. 
B)  RNA polymerase II binds to a promoter. 
C)  it proceeds from the 3' end to the 5' end. 
D)  the 5' end is capped with a methyl residue. 
A)  mRNA terminates at the 5' end. 
B)  RNA polymerase II binds to a promoter. 
C)  it proceeds from the 3' end to the 5' end. 
D)  the 5' end is capped with a methyl residue.

Question 3

A structural alteration of DNA in an organism that is caused by a physical or chemical agent is called:

Accepted Answer

A)  transcription. 
B)  translation. 
C)  mutation. 
D)  cloning. 
A)  transcription. 
B)  translation. 
C)  mutation. 
D)  cloning.

Question 4

How is it genetically possible for a child to type Rh-negative?

Accepted Answer

A)  Both parents are Dd. 
B)  Both parents are DD. 
C)  Mom is DD and Dad is Dd. 
D)  Sibling is Rh-positive. 
A)  Both parents are Dd. 
B)  Both parents are DD. 
C)  Mom is DD and Dad is Dd. 
D)  Sibling is Rh-positive.

Question 5

What blood group is the best example of codominantly inherited blood group genes?

Accepted Answer

A)  Rh 
B)  MN 
C)  Lewis 
D)  ABO 
A)  Rh 
B)  MN 
C)  Lewis 
D)  ABO

Question 6

The diploid chromosome number in humans is:

Accepted Answer

A)  12 
B)  23 
C)  46 
D)  92 
A)  12 
B)  23 
C)  46 
D)  92

Question 7

In which of the following circumstances will Hardy-Weinberg's principle fail?

Accepted Answer

A)  Mutation 
B)  Genetic drift 
C)  Nonrandom mating 
D)  All the above 
A)  Mutation 
B)  Genetic drift 
C)  Nonrandom mating 
D)  All the above

Question 8

A triple set of nucleotides is a:

Accepted Answer

A)  helix. 
B)  base. 
C)  codon. 
D)  template. 
A)  helix. 
B)  base. 
C)  codon. 
D)  template.

Question 9

In Mendel's law of separation, the first-filial generation is:

Accepted Answer

A)  recessive. 
B)  homozygous. 
C)  heterozygous. 
D)  autologous. 
A)  recessive. 
B)  homozygous. 
C)  heterozygous. 
D)  autologous.

Question 10

Which of the following best describes the process of mitosis?

Accepted Answer

A)  Cell division by which only one-half of the daughter cells produced are identical to the parent cell 
B)  Cell division of germ cells by which two successive divisions of the nucleus produce cells that contain half the number of chromosomes of somatic cells 
C)  Cell division that produces two daughter cells having the same number of chromosomes as the parent 
D)  Cell division that produces four daughter cells (4n) 
A)  Cell division by which only one-half of the daughter cells produced are identical to the parent cell 
B)  Cell division of germ cells by which two successive divisions of the nucleus produce cells that contain half the number of chromosomes of somatic cells 
C)  Cell division that produces two daughter cells having the same number of chromosomes as the parent 
D)  Cell division that produces four daughter cells (4n)

Question 11

A gene, such as the O gene, that produces no detectable product is called:

Accepted Answer

A)  an amorph. 
B)  a trait. 
C)  an allele. 
D)  recessive. 
A)  an amorph. 
B)  a trait. 
C)  an allele. 
D)  recessive.

Question 12

The two strands of DNA are: ; one runs in a 5' to 3' direction, and the other runs in a 3' to 5' direction.

Accepted Answer

A)  parallel 
B)  antiparallel 
C)  somatic 
D)  zigzag 
A)  parallel 
B)  antiparallel 
C)  somatic 
D)  zigzag

Question 13

The condition in which one chromosome has a copy of the gene and the other chromosome has that gene deleted or absent is referred to as:

Accepted Answer

A)  homozygous. 
B)  heterozygous. 
C)  hemizygous. 
D)  recessive. 
A)  homozygous. 
B)  heterozygous. 
C)  hemizygous. 
D)  recessive.

Question 14

How do restriction endonucleases function?

Accepted Answer

A)  Disrupt hydrogen bonding in DNA structure 
B)  Promote digestion of RNA 
C)  Cut DNA into smaller fragments 
D)  Terminate translation of mRNA 
A)  Disrupt hydrogen bonding in DNA structure 
B)  Promote digestion of RNA 
C)  Cut DNA into smaller fragments 
D)  Terminate translation of mRNA

Question 15

When 1,000 donors were tested, 75% were positive for C and 25% were negative for C; the gene frequency of C is:

Accepted Answer

A) 10. 
B) 1. 
C)  0.5. 
D)  25. 
A) 10. 
B) 1. 
C)  0.5. 
D)  25.

Question 16

A human gamete (egg or sperm) contains how many chromosomes?

Accepted Answer

A)  23 pairs 
B)  46 pairs 
C)  23 chromosomes 
D)  46 chromosomes 
A)  23 pairs 
B)  46 pairs 
C)  23 chromosomes 
D)  46 chromosomes

Question 17

Which of the following best describes the structure of human chromosomes?

Accepted Answer

A)  Linear strands of DNA wound around histones 
B)  Linear strands of RNA wrapped around histones 
C)  Tertiary structure of DNA wound around histones 
D)  Quaternary structure of DNA wound around histones 
A)  Linear strands of DNA wound around histones 
B)  Linear strands of RNA wrapped around histones 
C)  Tertiary structure of DNA wound around histones 
D)  Quaternary structure of DNA wound around histones

Question 18

When an individual is said to have blood group A, it refers to the individual's:

Accepted Answer

A)  alleles on the chromosome. 
B)  genotype. 
C)  phenotype. 
D)  haplotype. 
A)  alleles on the chromosome. 
B)  genotype. 
C)  phenotype. 
D)  haplotype.

Question 19

How many chromosomes do somatic cells of humans have?

Accepted Answer

A)  46 
B)  50 
C)  23 
D)  100 
A)  46 
B)  50 
C)  23 
D)  100

Question 20

Using the Hardy-Weinberg equation, if a total random population carried the dominant allele E and 20% carried the recessive allele e, what would the total percentage be for the recessive trait ee?

Accepted Answer

A)  64% 
B)  4% 
C)  16% 
D)  0.4% 
A)  64% 
B)  4% 
C)  16% 
D)  0.4%

Exam 2: Basic Genetics

Which of the following best describes classical genetics?

All of the following are included in transcription except:

A structural alteration of DNA in an organism that is caused by a physical or chemical agent is called:

How is it genetically possible for a child to type Rh-negative?

What blood group is the best example of codominantly inherited blood group genes?

The diploid chromosome number in humans is:

In which of the following circumstances will Hardy-Weinberg's principle fail?

A triple set of nucleotides is a:

In Mendel's law of separation, the first-filial generation is:

Which of the following best describes the process of mitosis?

A gene, such as the O gene, that produces no detectable product is called:

The two strands of DNA are: ; one runs in a 5' to 3' direction, and the other runs in a 3' to 5' direction.

The condition in which one chromosome has a copy of the gene and the other chromosome has that gene deleted or absent is referred to as:

How do restriction endonucleases function?

When 1,000 donors were tested, 75% were positive for C and 25% were negative for C; the gene frequency of C is:

A human gamete (egg or sperm) contains how many chromosomes?

Which of the following best describes the structure of human chromosomes?

When an individual is said to have blood group A, it refers to the individual's:

How many chromosomes do somatic cells of humans have?

Using the Hardy-Weinberg equation, if a total random population carried the dominant allele E and 20% carried the recessive allele e, what would the total percentage be for the recessive trait ee?

Red Blood Cells and Platelet Preservation: Historical Perspectives and Current Trends

Fundamentals of Immunology

Concepts in Molecular Biology

The Antiglobulin Test

The Abo Blood Group System

The Rh Blood Group System

Blood Group Terminology and Common Blood Groups

Uncommon Blood Groups

Detection and Identification of Antibodies

Pre-Transfusion Testing

Blood Bank Technologies and Automation

Donor Selection

Transfusion-Transmitted Diseases

Component Preparation

Transfusion Therapy

Adverse Effects of Blood Transfusion

Apheresis

Cellular Therapy in the Transplant Setting

Hemolytic Disease of the Fetus and Newborn

Autoimmune Hemolytic Anemias

Tissue Banking As Part of the Transfusion Service

The Hla System

Relationship Testing

Quality Management

Patient Blood Management

Transfusion Safety and Federal Regulatory Requirements

Laboratory Information Systems in the Blood Bank

Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services

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