Question 1

Bleeding disorders may be caused by:

Accepted Answer

A)  dysfunction of lymphocytes. 
B)  dysfunction of neutrophils. 
C)  dysfunction of platelets. 
D)  dysfunction of erythrocytes. 
A)  dysfunction of lymphocytes. 
B)  dysfunction of neutrophils. 
C)  dysfunction of platelets. 
D)  dysfunction of erythrocytes.

Question 2

Which of the following represents the final clerical check of a transfusion?

Accepted Answer

A)  The phlebotomist asks the patient to state his name and Social Security number and compares that information with the patient requisition. 
B)  The medical technologist compares the specimen label with computer information. 
C)  The nurse uses the patient's armband to compare patient identification with the patient crossmatch report and tags attached to the unit. 
D)  Two individuals verify affixing of proper labels to selected blood products. 
A)  The phlebotomist asks the patient to state his name and Social Security number and compares that information with the patient requisition. 
B)  The medical technologist compares the specimen label with computer information. 
C)  The nurse uses the patient's armband to compare patient identification with the patient crossmatch report and tags attached to the unit. 
D)  Two individuals verify affixing of proper labels to selected blood products.

Question 3

Why is whole blood contraindicated for patients with severe chronic anemia?

Accepted Answer

A)  These patients have a reduced number of red blood cells. 
B)  The plasma volume of these patients is decreased. 
C)  The plasma volume of these patients is increased. 
D)  These patients have an increased number of red blood cells. 
A)  These patients have a reduced number of red blood cells. 
B)  The plasma volume of these patients is decreased. 
C)  The plasma volume of these patients is increased. 
D)  These patients have an increased number of red blood cells.

Question 4

All blood components should be transfused within what time period to avoid bacterial contamination issues?

Accepted Answer

A)  4 hours 
B)  6 hours 
C)  8 hours 
D)  24 hours 
A)  4 hours 
B)  6 hours 
C)  8 hours 
D)  24 hours

Question 5

For which of the following transfusion candidates would CMV-negative blood be most likely indicated?

Accepted Answer

A)  Renal dialysis patients 
B)  Pregnant women 
C)  Transplant candidates 
D)  CMV seropositive patients 
A)  Renal dialysis patients 
B)  Pregnant women 
C)  Transplant candidates 
D)  CMV seropositive patients

Question 6

How is a coagulation factor unit defined?

Accepted Answer

A)  Activity in 1 mL of pooled plasma 
B)  100% activity in 1 unit/L 
C)  Activity in 100 units/mL 
D)  All of the above 
A)  Activity in 1 mL of pooled plasma 
B)  100% activity in 1 unit/L 
C)  Activity in 100 units/mL 
D)  All of the above

Question 7

Which type of filter is used in routine blood administration sets to remove gross clots from all blood products?

Accepted Answer

A)  Leukopoor 
B)  170 µm 
C)  100 µm 
D)  50 µm 
A)  Leukopoor 
B)  170 µm 
C)  100 µm 
D)  50 µm

Question 8

In the case of a need for massive transfusion in which a shortage of Rh-negative blood exists, which of these patients must not be switched to administration of Rh-positive blood if at all possible?

Accepted Answer

A)  35 year old male 
B)  85 year old male 
C)  35 year old female 
D)  85 year old female 
A)  35 year old male 
B)  85 year old male 
C)  35 year old female 
D)  85 year old female

Question 9

In anemia uncomplicated by low plasma proteins or shock, the transfusion of:

Accepted Answer

A)  whole blood is most desirable. 
B)  plasma is desirable. 
C)  packed red blood cells is most desirable. 
D)  fresh frozen plasma is most desirable. 
A)  whole blood is most desirable. 
B)  plasma is desirable. 
C)  packed red blood cells is most desirable. 
D)  fresh frozen plasma is most desirable.

Question 10

The rejection of the transplantation of platelets from one individual to another is termed or defined as:

Accepted Answer

A)  a hemolytic transfusion reaction. 
B)  platelet refractoriness. 
C)  graft-versus-host disease. 
D)  none of the above. 
A)  a hemolytic transfusion reaction. 
B)  platelet refractoriness. 
C)  graft-versus-host disease. 
D)  none of the above.

Question 11

The most important step in the safe administration of blood is to:

Accepted Answer

A)  perform compatibility testing accurately. 
B)  get an accurate patient history. 
C)  exclude disqualified donors. 
D)  accurately identify the donor unit and intended recipient. 
A)  perform compatibility testing accurately. 
B)  get an accurate patient history. 
C)  exclude disqualified donors. 
D)  accurately identify the donor unit and intended recipient.

Question 12

All of the following are characteristics of protein C except:

Accepted Answer

A)  it has a vitamin K dependent factor. 
B)  it has a serine protease inhibitor. 
C)  it enhances factors V and VIII. 
D)  it produces a hypercoagulable state. 
A)  it has a vitamin K dependent factor. 
B)  it has a serine protease inhibitor. 
C)  it enhances factors V and VIII. 
D)  it produces a hypercoagulable state.

Question 13

What transfusion therapy is indicated for a patient who is found to be refractory to random platelets?

Accepted Answer

A)  Irradiated random donor platelets 
B)  Random platelets from other donors 
C)  Apheresis platelets from an HLA-compatible donor 
D)  Neutralization of antiplatelet antibodies by type-specific platelets 
A)  Irradiated random donor platelets 
B)  Random platelets from other donors 
C)  Apheresis platelets from an HLA-compatible donor 
D)  Neutralization of antiplatelet antibodies by type-specific platelets

Question 14

What is the immunologic principle of RhIG administration?

Accepted Answer

A)  Anti-D attaches to Rh-positive cells of mother and are subsequently removed by cells of the reticuloendothelial system, preventing sensitization. 
B)  Anti-D attaches to Rh-positive cells of the infant in maternal circulation and are subsequently removed by cells of the reticuloendothelial system, preventing sensitization. 
C)  Anti-D attaches to Rh-negative cells of the infant in maternal circulation and are subsequently removed by cells of the reticuloendothelial system, preventing sensitization. 
D)  None of the above 
A)  Anti-D attaches to Rh-positive cells of mother and are subsequently removed by cells of the reticuloendothelial system, preventing sensitization. 
B)  Anti-D attaches to Rh-positive cells of the infant in maternal circulation and are subsequently removed by cells of the reticuloendothelial system, preventing sensitization. 
C)  Anti-D attaches to Rh-negative cells of the infant in maternal circulation and are subsequently removed by cells of the reticuloendothelial system, preventing sensitization. 
D)  None of the above

Question 15

In what disease state is acquired antithrombin III deficiency manifested?

Accepted Answer

A)  DIC 
B)  von Willebrand's disease 
C)  Liver disease 
D)  Lupus erythematosus 
A)  DIC 
B)  von Willebrand's disease 
C)  Liver disease 
D)  Lupus erythematosus

Question 16

Which of the following Rh-negative patients may be transfused with Rh-positive units when few O-negative units are available in an emergency?

Accepted Answer

A)  Pregnant woman 
B)  Middle-aged male 
C)  25-year-old female 
D)  Neonate 
A)  Pregnant woman 
B)  Middle-aged male 
C)  25-year-old female 
D)  Neonate

Question 17

What is suspected when the hematocrit has decreased by 4% and the total bilirubin level is increased 5 days after transfusion?

Accepted Answer

A)  Acute hemolytic transfusion reaction 
B)  Volume overload 
C)  Delayed hemolytic transfusion reaction 
D)  Urticarial reaction 
A)  Acute hemolytic transfusion reaction 
B)  Volume overload 
C)  Delayed hemolytic transfusion reaction 
D)  Urticarial reaction

Question 18

All coagulation factors are produced in the liver except:

Accepted Answer

A)  antihemophilic factor (AHF). 
B)  factor I. 
C)  vWF. 
D)  factor VII. 
A)  antihemophilic factor (AHF). 
B)  factor I. 
C)  vWF. 
D)  factor VII.

Question 19

Why are fresh blood units (less than 7 days old) preferred for a neonate transfusion?

Accepted Answer

A)  They reduce the risk of hyperkalemia. 
B)  They minimize 2,3 DPG levels. 
C)  They reduce the risk of hypokalemia. 
D)  They reduce the risk of hypernatremia. 
A)  They reduce the risk of hyperkalemia. 
B)  They minimize 2,3 DPG levels. 
C)  They reduce the risk of hypokalemia. 
D)  They reduce the risk of hypernatremia.

Question 20

How does 25% albumin induce diuresis in liver disease patients?

Accepted Answer

A)  Albumin inactivates antidiuretic hormone in diabetics. 
B)  Albumin solution acts with diuretic drugs to concentrate plasma, driving water into extravascular spaces. 
C)  Albumin solution acts with diuretics and brings extravascular water into vascular space to dilute albumin. 
D)  None of the above 
A)  Albumin inactivates antidiuretic hormone in diabetics. 
B)  Albumin solution acts with diuretic drugs to concentrate plasma, driving water into extravascular spaces. 
C)  Albumin solution acts with diuretics and brings extravascular water into vascular space to dilute albumin. 
D)  None of the above

Exam 16: Transfusion Therapy

Bleeding disorders may be caused by:

Which of the following represents the final clerical check of a transfusion?

Why is whole blood contraindicated for patients with severe chronic anemia?

All blood components should be transfused within what time period to avoid bacterial contamination issues?

For which of the following transfusion candidates would CMV-negative blood be most likely indicated?

How is a coagulation factor unit defined?

Which type of filter is used in routine blood administration sets to remove gross clots from all blood products?

In the case of a need for massive transfusion in which a shortage of Rh-negative blood exists, which of these patients must not be switched to administration of Rh-positive blood if at all possible?

In anemia uncomplicated by low plasma proteins or shock, the transfusion of:

The rejection of the transplantation of platelets from one individual to another is termed or defined as:

The most important step in the safe administration of blood is to:

All of the following are characteristics of protein C except:

What transfusion therapy is indicated for a patient who is found to be refractory to random platelets?

What is the immunologic principle of RhIG administration?

In what disease state is acquired antithrombin III deficiency manifested?

Which of the following Rh-negative patients may be transfused with Rh-positive units when few O-negative units are available in an emergency?

What is suspected when the hematocrit has decreased by 4% and the total bilirubin level is increased 5 days after transfusion?

All coagulation factors are produced in the liver except:

Why are fresh blood units (less than 7 days old) preferred for a neonate transfusion?

How does 25% albumin induce diuresis in liver disease patients?

Red Blood Cells and Platelet Preservation: Historical Perspectives and Current Trends

Basic Genetics

Fundamentals of Immunology

Concepts in Molecular Biology

The Antiglobulin Test

The Abo Blood Group System

The Rh Blood Group System

Blood Group Terminology and Common Blood Groups

Uncommon Blood Groups

Detection and Identification of Antibodies

Pre-Transfusion Testing

Blood Bank Technologies and Automation

Donor Selection

Transfusion-Transmitted Diseases

Component Preparation

Adverse Effects of Blood Transfusion

Apheresis

Cellular Therapy in the Transplant Setting

Hemolytic Disease of the Fetus and Newborn

Autoimmune Hemolytic Anemias

Tissue Banking As Part of the Transfusion Service

The Hla System

Relationship Testing

Quality Management

Patient Blood Management

Transfusion Safety and Federal Regulatory Requirements

Laboratory Information Systems in the Blood Bank

Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services

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