Question 1

Anti-Indian is able to cause:

Accepted Answer

A)  hemolytic transfusion reactions. 
B)  hemolytic disease of the fetus and newborn. 
C)  both of these 
D)  neither of these. 
A)  hemolytic transfusion reactions. 
B)  hemolytic disease of the fetus and newborn. 
C)  both of these 
D)  neither of these.

Question 2

Which antigen is destroyed by DTT?

Accepted Answer

A)  Dombrock 
B)  JMH 
C)  Knops 
D)  All of these 
A)  Dombrock 
B)  JMH 
C)  Knops 
D)  All of these

Question 3

Anti-Vel antibody is usually:

Accepted Answer

A)  IgG 
B)  IgM 
C)  Both 
D)  Neither 
A)  IgG 
B)  IgM 
C)  Both 
D)  Neither

Question 4

How does Anti-LW usually react?

Accepted Answer

A)  Weakly with D+ RBCs 
B)  Strongly with D- RBCs from adults 
C)  Weakly with D- RBCs from cord blood 
D)  Negatively with Rhnull RBCs 
A)  Weakly with D+ RBCs 
B)  Strongly with D- RBCs from adults 
C)  Weakly with D- RBCs from cord blood 
D)  Negatively with Rhnull RBCs

Question 5

Bg antibodies are primarily directed toward antigenic determinants present on:

Accepted Answer

A)  white blood cells. 
B)  red blood cells. 
C)  platelets. 
D)  meso cells. 
A)  white blood cells. 
B)  red blood cells. 
C)  platelets. 
D)  meso cells.

Question 6

Knops antigens are present in most populations at a rate of:

Accepted Answer

A)  10% 
B)  30% 
C)  60% 
D)  90% 
A)  10% 
B)  30% 
C)  60% 
D)  90%

Question 7

Cromer system antibodies:

Accepted Answer

A)  are usually IgG. 
B)  do not cause HDFN. 
C)  are expressed on placentas. 
D)  are all of these. 
A)  are usually IgG. 
B)  do not cause HDFN. 
C)  are expressed on placentas. 
D)  are all of these.

Question 8

Low prevalence Gerbich-negative phenotypes include all of these EXCEPT

Accepted Answer

A)  Ana 
B)  Ge2 
C)  Lsa 
D)  Wb 
A)  Ana 
B)  Ge2 
C)  Lsa 
D)  Wb

Question 9

Which antibody is viewed to be clinically significant because of its association with HTR and HDN?

Accepted Answer

A)  Anti-Bga 
B)  Anti-Kna 
C)  Anti-Dib 
D)  Anti-Cha 
A)  Anti-Bga 
B)  Anti-Kna 
C)  Anti-Dib 
D)  Anti-Cha

Question 10

Which of the following antigens is NOT part of the Rh-Associated Glycoprotein System?

Accepted Answer

A)  DCE 
B)  DSLK 
C)  Duclos 
D)  Ola 
A)  DCE 
B)  DSLK 
C)  Duclos 
D)  Ola

Question 11

Antigens in the CH/RG blood group system are described as:

Accepted Answer

A)  resistant to ficin treatment. 
B)  antithetical partners. 
C)  well developed on cord cells. 
D)  adsorbed onto the red blood cell membrane. 
A)  resistant to ficin treatment. 
B)  antithetical partners. 
C)  well developed on cord cells. 
D)  adsorbed onto the red blood cell membrane.

Question 12

ISBT nomenclature for the Xg System is

Accepted Answer

A)  002 
B)  006 
C)  012 
D)  024 
A)  002 
B)  006 
C)  012 
D)  024

Question 13

The high-incidence Gya, Hy, and Joa antigens belong to which blood group system?

Accepted Answer

A)  Wr 
B)  DI 
C)  DO 
D)  Sc 
A)  Wr 
B)  DI 
C)  DO 
D)  Sc

Question 14

Where might you expect anti-Ytb to react in antibody screening?

Accepted Answer

A)  Immediate spin phase 
B)  37°C phase 
C)  IAT phase 
D)  All of the above 
A)  Immediate spin phase 
B)  37°C phase 
C)  IAT phase 
D)  All of the above

Question 15

Why was the Forssman system originally thought to be an A subgroup?

Accepted Answer

A)  Cross-reactivity with monoclonal anti-A1 
B)  Cross-reactivity with monoclonal anti-A2 
C)  Cross-reactivity with polycolonal anti-A 
D)  No cross-reactivity with polycolonal anti-A 
A)  Cross-reactivity with monoclonal anti-A1 
B)  Cross-reactivity with monoclonal anti-A2 
C)  Cross-reactivity with polycolonal anti-A 
D)  No cross-reactivity with polycolonal anti-A

Question 16

A plasma inhibition study was performed on a patient whose serum sample reacted +/- on all panel cells at AHG. Three sets of A, B, C tubes were set up according to the following scheme: Tube A had 2 drops of patient serum and 1 drop of Ch(a+) Rg(a-) plasma.
Tube B had 2 drops of patient serum and 1 drop of Ch(a-) Rg(a+) plasma.
Tube C had 2 drops of patient serum and 1 drop of Ch(a+) Rg(a+) plasma.
Screening cells were added in triplicate and incubated for 60 minutes at 37°C. The antiglobulin test was performed. All three A tubes reacted at 2+, and the B and C tubes were negative. What antibody is indicated?

Accepted Answer

A)  Anti-Cha 
B)  Anti-Rga 
C)  Another alloantibody 
D)  None of the above 
A)  Anti-Cha 
B)  Anti-Rga 
C)  Another alloantibody 
D)  None of the above

Question 17

is an antigen in the high-prevalence series (901) that is found in saliva and urine. The corresponding antibody typically reacts at the AHG phase and produces a characteristic refractile, mixed-field reaction.

Accepted Answer

A)  Vel 
B)  JMH 
C)  Lan 
D)  Sda 
A)  Vel 
B)  JMH 
C)  Lan 
D)  Sda

Question 18

Most the antigens in the blood group collections are

Accepted Answer

A)  high frequency. 
B)  low frequency. 
C)  Both. 
D)  Neither. 
A)  high frequency. 
B)  low frequency. 
C)  Both. 
D)  Neither.

Question 19

The Dia and Dib antigens are located on:

Accepted Answer

A)  complement receptor one (CRI). 
B)  erythrocyte acetylcholinesterase. 
C)  the anion exchange molecule (AE-1). 
D)  channel-forming integral protein (CHIP). 
A)  complement receptor one (CRI). 
B)  erythrocyte acetylcholinesterase. 
C)  the anion exchange molecule (AE-1). 
D)  channel-forming integral protein (CHIP).

Question 20

Anti-Vel is able to cause:

Accepted Answer

A)  in vitro but not in vivo hemolysis. 
B)  in vivo but not in vitro hemolysis. 
C)  both in vitro and in vivo hemolysis. 
D)  neither in vitro nor in vivo hemolysis. 
A)  in vitro but not in vivo hemolysis. 
B)  in vivo but not in vitro hemolysis. 
C)  both in vitro and in vivo hemolysis. 
D)  neither in vitro nor in vivo hemolysis.

Exam 9: Uncommon Blood Groups

Anti-Indian is able to cause:

Which antigen is destroyed by DTT?

Anti-Vel antibody is usually:

How does Anti-LW usually react?

Bg antibodies are primarily directed toward antigenic determinants present on:

Knops antigens are present in most populations at a rate of:

Cromer system antibodies:

Low prevalence Gerbich-negative phenotypes include all of these EXCEPT

Which antibody is viewed to be clinically significant because of its association with HTR and HDN?

Which of the following antigens is NOT part of the Rh-Associated Glycoprotein System?

Antigens in the CH/RG blood group system are described as:

ISBT nomenclature for the Xg System is

The high-incidence Gya, Hy, and Joa antigens belong to which blood group system?

Where might you expect anti-Ytb to react in antibody screening?

Why was the Forssman system originally thought to be an A subgroup?

is an antigen in the high-prevalence series (901) that is found in saliva and urine. The corresponding antibody typically reacts at the AHG phase and produces a characteristic refractile, mixed-field reaction.

Most the antigens in the blood group collections are

The Dia and Dib antigens are located on:

Anti-Vel is able to cause:

Red Blood Cells and Platelet Preservation: Historical Perspectives and Current Trends

Basic Genetics

Fundamentals of Immunology

Concepts in Molecular Biology

The Antiglobulin Test

The Abo Blood Group System

The Rh Blood Group System

Blood Group Terminology and Common Blood Groups

Detection and Identification of Antibodies

Pre-Transfusion Testing

Blood Bank Technologies and Automation

Donor Selection

Transfusion-Transmitted Diseases

Component Preparation

Transfusion Therapy

Adverse Effects of Blood Transfusion

Apheresis

Cellular Therapy in the Transplant Setting

Hemolytic Disease of the Fetus and Newborn

Autoimmune Hemolytic Anemias

Tissue Banking As Part of the Transfusion Service

The Hla System

Relationship Testing

Quality Management

Patient Blood Management

Transfusion Safety and Federal Regulatory Requirements

Laboratory Information Systems in the Blood Bank

Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services

Filters

The high-incidence Gy^a, Hy, and Jo^a antigens belong to which blood group system?

Where might you expect anti-Yt^b to react in antibody screening?

The Di^a and Di^b antigens are located on: