Question 1

Approximately what percentage of the black population are s-?

Accepted Answer

A)  70% 
B)  98% 
C)  3% 
D)  25% 
A)  70% 
B)  98% 
C)  3% 
D)  25%

Question 2

What red blood cell antigens do McLeod individuals express?

Accepted Answer

A)  TracekKpbJsbK11 
B)  KmKx 
C)  None 
D)  KkKpbJsa 
A)  TracekKpbJsbK11 
B)  KmKx 
C)  None 
D)  KkKpbJsa

Question 3

How is Le(y) formed?

Accepted Answer

A)  Fucose-B(1-4) GlcNAc is added to type 1 chain oligosaccharide. 
B)  Fucose-A(1-3) GlcNAc is added to type 2H precursor substance. 
C)  Fucose-A(1-4) GlcNAc is added to type 2H precursor substance. 
D)  Fucose-B(1-3) GlcNAc is added to type 2 chain oligosaccharide. 
A)  Fucose-B(1-4) GlcNAc is added to type 1 chain oligosaccharide. 
B)  Fucose-A(1-3) GlcNAc is added to type 2H precursor substance. 
C)  Fucose-A(1-4) GlcNAc is added to type 2H precursor substance. 
D)  Fucose-B(1-3) GlcNAc is added to type 2 chain oligosaccharide.

Question 4

Lewis cell-bound antigens absorbed from plasma onto the red blood cell membranes are:

Accepted Answer

A)  glycoproteins. 
B)  glycolipids. 
C)  sphingolipids. 
D)  ceramides. 
A)  glycoproteins. 
B)  glycolipids. 
C)  sphingolipids. 
D)  ceramides.

Question 5

Anti-Lea, which is reactive at the Coombs phase, may cause what kind of hemolysis?

Accepted Answer

A)  In vivo 
B)  In vitro 
C)  Intravascular 
D)  None of the above 
A)  In vivo 
B)  In vitro 
C)  Intravascular 
D)  None of the above

Question 6

A person who inherits alleles Fya and Fyb will carry which antigens on their red blood cells?

Accepted Answer

A)  Only Fya antigen 
B)  Only Fyb antigen 
C)  Both Fya and Fyb antigen 
D)  Neither Fya or Fyb antigen 
A)  Only Fya antigen 
B)  Only Fyb antigen 
C)  Both Fya and Fyb antigen 
D)  Neither Fya or Fyb antigen

Question 7

Which of the following statements is false?

Accepted Answer

A)  Lewis antibodies do not bind complement. 
B)  Lewis antibodies may cause hemolytic reactions if detectable at 37°C. 
C)  Lewis antibodies are IgM; therefore, they cannot cross the placenta and cause hemolytic disease of the newborn. 
D)  Lewis antigens are finally developed around age 6. 
A)  Lewis antibodies do not bind complement. 
B)  Lewis antibodies may cause hemolytic reactions if detectable at 37°C. 
C)  Lewis antibodies are IgM; therefore, they cannot cross the placenta and cause hemolytic disease of the newborn. 
D)  Lewis antigens are finally developed around age 6.

Question 8

The Miltenberger subsystem is related to what major blood group system?

Accepted Answer

A)  Rh 
B)  Kell 
C)  P 
D)  MNSs 
A)  Rh 
B)  Kell 
C)  P 
D)  MNSs

Question 9

The Kell gene is located on the long arm of which chromosome?

Accepted Answer

A)  5 
B)  7 
C)  9 
D)  11 
A)  5 
B)  7 
C)  9 
D)  11

Question 10

At which phase are Lewis antibodies usually detected?

Accepted Answer

A)  Immediate spin 
B)  37°C 
C)  Coombs 
D)  All of the above 
A)  Immediate spin 
B)  37°C 
C)  Coombs 
D)  All of the above

Question 11

The gene that codes for P1 is located on which chromosome?

Accepted Answer

A)  22 
B)  12 
C)  9 
D)  4 
A)  22 
B)  12 
C)  9 
D)  4

Question 12

How do MN antigens differ in their biochemical protein structure?

Accepted Answer

A)  M contains serine at position 1 and N contains glycine. 
B)  N contains glutamic acid at position 5 and M contains glycine. 
C)  N contains glycine at position 5 and M contains arginine. 
D)  M contains serine at position 1 and N contains lysine. 
A)  M contains serine at position 1 and N contains glycine. 
B)  N contains glutamic acid at position 5 and M contains glycine. 
C)  N contains glycine at position 5 and M contains arginine. 
D)  M contains serine at position 1 and N contains lysine.

Question 13

Anti-Lua is destroyed by what enzyme?

Accepted Answer

A)  Trypsin 
B)  Ficin 
C)  Papain 
D)  All of the above 
A)  Trypsin 
B)  Ficin 
C)  Papain 
D)  All of the above

Question 14

What is the biochemical structure of the P system antigens?

Accepted Answer

A)  Phospholipid 
B)  Glycophorin B 
C)  Glycosphingolipids 
D)  Glycophorin A 
A)  Phospholipid 
B)  Glycophorin B 
C)  Glycosphingolipids 
D)  Glycophorin A

Question 15

The Fy5 antigen has been shown to be the result of an interaction between Duffy genes and:

Accepted Answer

A)  Lewis 
B)  ABO 
C)  Rh 
D)  Kidd 
A)  Lewis 
B)  ABO 
C)  Rh 
D)  Kidd

Question 16

Which of the following statements regarding individuals who are Fy(a-b-) is true?

Accepted Answer

A)  The presence of Fyb in the tissue of individuals who are black who are Fy(a-b-) prevents those individuals from forming Anti-Fyb. 
B)  The presence of Fya substance in individuals who are white who are Fy(a-b-) prevents those individuals from forming Anti-Fya. 
C)  All individuals that are Fy(a-b-) are likely to form anti Fyb if exposed to the Fyb antigen. 
D)  Anti Fyb can only be produced from individuals that have inherited the Duffy gene. 
A)  The presence of Fyb in the tissue of individuals who are black who are Fy(a-b-) prevents those individuals from forming Anti-Fyb. 
B)  The presence of Fya substance in individuals who are white who are Fy(a-b-) prevents those individuals from forming Anti-Fya. 
C)  All individuals that are Fy(a-b-) are likely to form anti Fyb if exposed to the Fyb antigen. 
D)  Anti Fyb can only be produced from individuals that have inherited the Duffy gene.

Question 17

The Duffy antigens have mobility characteristics similar to what other antigenic structure?

Accepted Answer

A)  Ss-SGP 
B)  MN-SGP 
C)  H precursor structure 
D)  Jka protein 
A)  Ss-SGP 
B)  MN-SGP 
C)  H precursor structure 
D)  Jka protein

Question 18

Which group of antigens below best represents the definition of high-frequency antigens?

Accepted Answer

A)  Jsb, Kpb 
B)  K, k 
C)  Kpa, Jsa 
D)  Jka, K 
A)  Jsb, Kpb 
B)  K, k 
C)  Kpa, Jsa 
D)  Jka, K

Question 19

What MN phenotype is found in highest frequency in the white population?

Accepted Answer

A)  M+N+ 
B)  M+N- 
C)  M-N- 
D)  M-N+ 
A)  M+N+ 
B)  M+N- 
C)  M-N- 
D)  M-N+

Question 20

Persons who are genetically P1 may serologically type as P2 because of:

Accepted Answer

A)  inheritance of the In(Lu) gene. 
B)  inheritance of the p gene. 
C)  presence of anti-P1 in their serum. 
D)  depressed antigen expression. 
A)  inheritance of the In(Lu) gene. 
B)  inheritance of the p gene. 
C)  presence of anti-P1 in their serum. 
D)  depressed antigen expression.

Exam 8: Blood Group Terminology and Common Blood Groups

Approximately what percentage of the black population are s-?

What red blood cell antigens do McLeod individuals express?

How is Le(y) formed?

Lewis cell-bound antigens absorbed from plasma onto the red blood cell membranes are:

Anti-Lea, which is reactive at the Coombs phase, may cause what kind of hemolysis?

A person who inherits alleles Fya and Fyb will carry which antigens on their red blood cells?

Which of the following statements is false?

The Miltenberger subsystem is related to what major blood group system?

The Kell gene is located on the long arm of which chromosome?

At which phase are Lewis antibodies usually detected?

The gene that codes for P1 is located on which chromosome?

How do MN antigens differ in their biochemical protein structure?

Anti-Lua is destroyed by what enzyme?

What is the biochemical structure of the P system antigens?

The Fy5 antigen has been shown to be the result of an interaction between Duffy genes and:

Which of the following statements regarding individuals who are Fy(a-b-) is true?

The Duffy antigens have mobility characteristics similar to what other antigenic structure?

Which group of antigens below best represents the definition of high-frequency antigens?

What MN phenotype is found in highest frequency in the white population?

Persons who are genetically P1 may serologically type as P2 because of:

Red Blood Cells and Platelet Preservation: Historical Perspectives and Current Trends

Basic Genetics

Fundamentals of Immunology

Concepts in Molecular Biology

The Antiglobulin Test

The Abo Blood Group System

The Rh Blood Group System

Uncommon Blood Groups

Detection and Identification of Antibodies

Pre-Transfusion Testing

Blood Bank Technologies and Automation

Donor Selection

Transfusion-Transmitted Diseases

Component Preparation

Transfusion Therapy

Adverse Effects of Blood Transfusion

Apheresis

Cellular Therapy in the Transplant Setting

Hemolytic Disease of the Fetus and Newborn

Autoimmune Hemolytic Anemias

Tissue Banking As Part of the Transfusion Service

The Hla System

Relationship Testing

Quality Management

Patient Blood Management

Transfusion Safety and Federal Regulatory Requirements

Laboratory Information Systems in the Blood Bank

Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services

Filters

Anti-Le^a, which is reactive at the Coombs phase, may cause what kind of hemolysis?

A person who inherits alleles Fy^a and Fy^b will carry which antigens on their red blood cells?

The gene that codes for P₁ is located on which chromosome?

Anti-Lu^a is destroyed by what enzyme?

Persons who are genetically P₁ may serologically type as P₂ because of: