Question 1

The homozygous phenotype Fy(a+b-) has antigenic Fy sites than heterozygous cells, Fy(a+b+).

Accepted Answer

A)  more 
B)  fewer 
C)  weaker 
D)  none of the above 
A)  more 
B)  fewer 
C)  weaker 
D)  none of the above

Question 2

How are lipids dissociated from the red blood cell membrane for biochemical studies?

Accepted Answer

A)  Increased pH 
B)  Ion exchange 
C)  Sodium dodecyl sulfate 
D)  Organic solvents 
A)  Increased pH 
B)  Ion exchange 
C)  Sodium dodecyl sulfate 
D)  Organic solvents

Question 3

Anti-I is found in association with what microorganism?

Accepted Answer

A)  Mycoplasma pneumoniae 
B)  Treponema pallidum 
C)  Escherichia coli 
D)  Proteus vulgaris 
A)  Mycoplasma pneumoniae 
B)  Treponema pallidum 
C)  Escherichia coli 
D)  Proteus vulgaris

Question 4

Why was U antigen included in the MNSs blood group system?

Accepted Answer

A)  U is enhanced by enzyme treatment. 
B)  All U-negative red blood cells were also S-s-. 
C)  All U-positive red blood cells were also S+s+. 
D)  All U-negative red blood cells were also M-N-. 
A)  U is enhanced by enzyme treatment. 
B)  All U-negative red blood cells were also S-s-. 
C)  All U-positive red blood cells were also S+s+. 
D)  All U-negative red blood cells were also M-N-.

Question 5

What does the type 1 chain refer to?

Accepted Answer

A)  Alpha linkage of the number 1 carbon of galactose to the number 3 carbon of N-acetylglucosamine residue of precursor structure 
B)  Beta linkage of the number 2 carbon of galactose to the number 4 carbon of N-acetylglucosamine residue of precursor structure 
C)  Beta linkage of the number 1 carbon of galactose to the number 3 carbon of N-acetylglucosamine residue of precursor structure 
D)  Alpha linkage of the number 1 carbon of galactose to the number 4 carbon of N-acetylglucosamine residue to precursor structure 
A)  Alpha linkage of the number 1 carbon of galactose to the number 3 carbon of N-acetylglucosamine residue of precursor structure 
B)  Beta linkage of the number 2 carbon of galactose to the number 4 carbon of N-acetylglucosamine residue of precursor structure 
C)  Beta linkage of the number 1 carbon of galactose to the number 3 carbon of N-acetylglucosamine residue of precursor structure 
D)  Alpha linkage of the number 1 carbon of galactose to the number 4 carbon of N-acetylglucosamine residue to precursor structure

Question 6

What anemia will result in an increased expression of i antigen, which exceeds that found on control cord cells?

Accepted Answer

A)  Sideroblastic anemia 
B)  CDA type I 
C)  CDA type II 
D)  CDA type III 
A)  Sideroblastic anemia 
B)  CDA type I 
C)  CDA type II 
D)  CDA type III

Question 7

Type I H antigen in secretions is a product of which of the following genes?

Accepted Answer

A)  H 
B)  Le 
C)  Se 
D)  le 
A)  H 
B)  Le 
C)  Se 
D)  le

Question 8

What percentage of the white population inherits the Le gene?

Accepted Answer

A)  50% 
B)  90% 
C)  10% 
D)  25% 
A)  50% 
B)  90% 
C)  10% 
D)  25%

Question 9

What class of immunoglobulin makes up anti-Lua?

Accepted Answer

A)  IgA 
B)  IgM 
C)  IgG 
D)  All of the above 
A)  IgA 
B)  IgM 
C)  IgG 
D)  All of the above

Question 10

A patient who recently recovered from a Mycoplasma pneumoniae infection may develop which antibody?

Accepted Answer

A)  Anti-I 
B)  Anti-i 
C)  Anti-P 
D)  Anti-p 
A)  Anti-I 
B)  Anti-i 
C)  Anti-P 
D)  Anti-p

Question 11

Anti-M was detected in a 27-year-old man before surgery. Units negative for M antigen were not available; however, the units were approved for transfusion when major crossmatch using M+N+ donor cells and patient serum resulted in:

Accepted Answer

A)  IS = 1+, 37 = 1+, AHG = 0 
B)  IS = 1+, 37 = 0, AHG = 0 
C)  IS = 3+, 37 = 2+, AHG = 1+ 
D)  IS = 2+, 37 = 1+, AHG = 0 
A)  IS = 1+, 37 = 1+, AHG = 0 
B)  IS = 1+, 37 = 0, AHG = 0 
C)  IS = 3+, 37 = 2+, AHG = 1+ 
D)  IS = 2+, 37 = 1+, AHG = 0

Question 12

Persons who are negative for Duffy antigens are less likely to contract which of the following diseases?

Accepted Answer

A)  Chicken pox 
B)  Influenza 
C)  Malaria 
D)  Polio 
A)  Chicken pox 
B)  Influenza 
C)  Malaria 
D)  Polio

Question 13

Persons who inherit the Se and Le genes will have A or B glycolipids in plasma than persons who are Se le.

Accepted Answer

A)  more 
B)  fewer 
C)  inactive 
D)  none of the above 
A)  more 
B)  fewer 
C)  inactive 
D)  none of the above

Question 14

Which has been shown to define the Duffy receptor that Plasmodium vivax uses to penetrate red blood cells?

Accepted Answer

A)  Anti-Fy3 
B)  Anti-Fy5 
C)  Anti-Fy6 
D)  Anti-Fy4 
A)  Anti-Fy3 
B)  Anti-Fy5 
C)  Anti-Fy6 
D)  Anti-Fy4

Question 15

At birth, infant cells are rich in , and is nearly undetectable.

Accepted Answer

A)  I/i 
B)  I/H 
C)  i/I 
D)  H/i 
A)  I/i 
B)  I/H 
C)  i/I 
D)  H/i

Question 16

Anti-Lu3 will be compatible with donor blood from individuals with which of the following phenotypes?

Accepted Answer

A)  Lu(a-b+) 
B)  Lu (a+b-) 
C)  Lu (a-b-) 
D)  Lu (a+b+) 
A)  Lu(a-b+) 
B)  Lu (a+b-) 
C)  Lu (a-b-) 
D)  Lu (a+b+)

Question 17

What is unique about the Kpa antigen?

Accepted Answer

A)  It occurs in as high a frequency as its antithetical partner, Kpb. 
B)  It suppresses the expression of k and Jsb. 
C)  It enhances the expression of k and Jsb. 
D)  Its inheritance is most often a result of a consanguineous marriage. 
A)  It occurs in as high a frequency as its antithetical partner, Kpb. 
B)  It suppresses the expression of k and Jsb. 
C)  It enhances the expression of k and Jsb. 
D)  Its inheritance is most often a result of a consanguineous marriage.

Question 18

Which of the following blood groups is inherited from the parents but absent at birth?

Accepted Answer

A)  P1 
B)  Lewis 
C)  Lutheran 
D)  Fya 
A)  P1 
B)  Lewis 
C)  Lutheran 
D)  Fya

Question 19

Persons who phenotype as Fy(a-b-) are resistant to infection by which organism?

Accepted Answer

A)  Plasmodium falciparum 
B)  Plasmodium vivax 
C)  Plasmodium ovale 
D)  Plasmodium malariae 
A)  Plasmodium falciparum 
B)  Plasmodium vivax 
C)  Plasmodium ovale 
D)  Plasmodium malariae

Question 20

Which of the following distinguishes the recessive LuLu gene from the dominant In(Lu) gene?

Accepted Answer

A)  Normal expression of P1 
B)  Abnormal expression of P1 
C)  Expression of the Lu(a-b-) phenotype 
D)  Expression of trace amounts of i antigen 
A)  Normal expression of P1 
B)  Abnormal expression of P1 
C)  Expression of the Lu(a-b-) phenotype 
D)  Expression of trace amounts of i antigen

Exam 8: Blood Group Terminology and Common Blood Groups

The homozygous phenotype Fy(a+b-) has antigenic Fy sites than heterozygous cells, Fy(a+b+).

How are lipids dissociated from the red blood cell membrane for biochemical studies?

Anti-I is found in association with what microorganism?

Why was U antigen included in the MNSs blood group system?

What does the type 1 chain refer to?

What anemia will result in an increased expression of i antigen, which exceeds that found on control cord cells?

Type I H antigen in secretions is a product of which of the following genes?

What percentage of the white population inherits the Le gene?

What class of immunoglobulin makes up anti-Lua?

A patient who recently recovered from a Mycoplasma pneumoniae infection may develop which antibody?

Anti-M was detected in a 27-year-old man before surgery. Units negative for M antigen were not available; however, the units were approved for transfusion when major crossmatch using M+N+ donor cells and patient serum resulted in:

Persons who are negative for Duffy antigens are less likely to contract which of the following diseases?

Persons who inherit the Se and Le genes will have A or B glycolipids in plasma than persons who are Se le.

Which has been shown to define the Duffy receptor that Plasmodium vivax uses to penetrate red blood cells?

At birth, infant cells are rich in , and is nearly undetectable.

Anti-Lu3 will be compatible with donor blood from individuals with which of the following phenotypes?

What is unique about the Kpa antigen?

Which of the following blood groups is inherited from the parents but absent at birth?

Persons who phenotype as Fy(a-b-) are resistant to infection by which organism?

Which of the following distinguishes the recessive LuLu gene from the dominant In(Lu) gene?

Red Blood Cells and Platelet Preservation: Historical Perspectives and Current Trends

Basic Genetics

Fundamentals of Immunology

Concepts in Molecular Biology

The Antiglobulin Test

The Abo Blood Group System

The Rh Blood Group System

Uncommon Blood Groups

Detection and Identification of Antibodies

Pre-Transfusion Testing

Blood Bank Technologies and Automation

Donor Selection

Transfusion-Transmitted Diseases

Component Preparation

Transfusion Therapy

Adverse Effects of Blood Transfusion

Apheresis

Cellular Therapy in the Transplant Setting

Hemolytic Disease of the Fetus and Newborn

Autoimmune Hemolytic Anemias

Tissue Banking As Part of the Transfusion Service

The Hla System

Relationship Testing

Quality Management

Patient Blood Management

Transfusion Safety and Federal Regulatory Requirements

Laboratory Information Systems in the Blood Bank

Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services

Filters

What class of immunoglobulin makes up anti-Lu^a?

What is unique about the Kp^a antigen?