Question 1

What is the ISBT designation for the Lutheran blood group system?

Accepted Answer

A)  LN 
B)  LU 
C)  LT 
D)  LR 
A)  LN 
B)  LU 
C)  LT 
D)  LR

Question 2

What substances would be present in the saliva of a person with the LeLe HH SeSe AA genotype?

Accepted Answer

A)  A, H 
B)  A, B, H 
C)  H, B, Lea, Leb 
D)  A, H, Lea, Leb 
A)  A, H 
B)  A, B, H 
C)  H, B, Lea, Leb 
D)  A, H, Lea, Leb

Question 3

A patient who had a viral infection suspected to be Infectious mononucleosis may develop which antibody?

Accepted Answer

A)  Anti-I 
B)  Anti-i 
C)  Anti-P 
D)  Anti-p 
A)  Anti-I 
B)  Anti-i 
C)  Anti-P 
D)  Anti-p

Question 4

What sample requirement is essential for identification of a Kidd antibody?

Accepted Answer

A)  Fresh whole blood 
B)  Fresh serum or plasma 
C)  Fasting sample 
D)  Sample on ice 
A)  Fresh whole blood 
B)  Fresh serum or plasma 
C)  Fasting sample 
D)  Sample on ice

Question 5

Which antigen(s) is/are antithetical partner(s) to s?

Accepted Answer

A)  MN 
B)  E 
C)  U 
D)  f 
A)  MN 
B)  E 
C)  U 
D)  f

Question 6

All of the following are characteristics of Kidd antibodies except:

Accepted Answer

A)  IgG immunoglobulins. 
B)  ability to bind complement. 
C)  naturally occurring. 
D)  exhibit dosage. 
A)  IgG immunoglobulins. 
B)  ability to bind complement. 
C)  naturally occurring. 
D)  exhibit dosage.

Question 7

All of the following are characteristics of the Ena antigen except:

Accepted Answer

A)  it is a high-frequency antigen. 
B)  it is a low-frequency antigen. 
C)  individuals negative for Ena lack MN-SGP. 
D)  most Ena-negative individuals produce anti-Ena. 
A)  it is a high-frequency antigen. 
B)  it is a low-frequency antigen. 
C)  individuals negative for Ena lack MN-SGP. 
D)  most Ena-negative individuals produce anti-Ena.

Question 8

Lewis antibodies are of what immunoglobulin class?

Accepted Answer

A)  IgM 
B)  IgG 
C)  IgA 
D)  IgE 
A)  IgM 
B)  IgG 
C)  IgA 
D)  IgE

Question 9

Why is HDN not a consideration when the mother possesses anti-P1 in her serum?

Accepted Answer

A)  Anti-P1 is an IgM antibody. 
B)  P1 antigen is poorly expressed at birth. 
C)  Anti-P1 does not react at 37°C. 
D)  Anti-P1 is a naturally occurring antibody. 
A)  Anti-P1 is an IgM antibody. 
B)  P1 antigen is poorly expressed at birth. 
C)  Anti-P1 does not react at 37°C. 
D)  Anti-P1 is a naturally occurring antibody.

Question 10

What serologic factor distinguishes anti-Fy3 from anti-Fya or anti-Fyb?

Accepted Answer

A)  It is not destroyed by enzymes. 
B)  It is an IgM antibody. 
C)  It does not bind complement. 
D)  It does show dosage. 
A)  It is not destroyed by enzymes. 
B)  It is an IgM antibody. 
C)  It does not bind complement. 
D)  It does show dosage.

Question 11

What is the most common Kidd phenotype in the black population?

Accepted Answer

A)  Jk(a+b-) 
B)  Jk(a+b+) 
C)  Jk(a-b+) 
D)  Jk(a-b-) 
A)  Jk(a+b-) 
B)  Jk(a+b+) 
C)  Jk(a-b+) 
D)  Jk(a-b-)

Question 12

Why do En(a-) individuals have a reduced chance of infection with Plasmodium falciparum?

Accepted Answer

A)  There is a reduction in N-acetylneuraminic acid. 
B)  There is an increase in N-acetylneuraminic acid. 
C)  GPB is in an altered state. 
D)  There is a reduction in N-acetylgalactosamine. 
A)  There is a reduction in N-acetylneuraminic acid. 
B)  There is an increase in N-acetylneuraminic acid. 
C)  GPB is in an altered state. 
D)  There is a reduction in N-acetylgalactosamine.

Question 13

At what age does I antigen become detectable on infant cells?

Accepted Answer

A)  1 year 
B)  18 months 
C)  4 years 
D)  1 month 
A)  1 year 
B)  18 months 
C)  4 years 
D)  1 month

Question 14

What sequence of antigens coincides with strongest immunogen to weakest immunogen?

Accepted Answer

A)  D, Fya, Fyb, K 
B)  D, K, Fya, Fyb 
C)  Fya, Fyb, D, K 
D)  K, Fya, Fyb, D 
A)  D, Fya, Fyb, K 
B)  D, K, Fya, Fyb 
C)  Fya, Fyb, D, K 
D)  K, Fya, Fyb, D

Question 15

Anti-N is known to occur in patients undergoing dialysis with equipment sterilized by formaldehyde?

Accepted Answer

A)  cancer 
B)  thyroid 
C)  renal 
D)  immunocompromised 
A)  cancer 
B)  thyroid 
C)  renal 
D)  immunocompromised

Question 16

On which malaria receptor site is Duffy antigen dependent?

Accepted Answer

A)  Attachment receptor 
B)  Junction receptor 
C)  Ligand receptor 
D)  None of the above 
A)  Attachment receptor 
B)  Junction receptor 
C)  Ligand receptor 
D)  None of the above

Question 17

What is the etiology of dialysis-associated anti-N?

Accepted Answer

A)  Formaldehyde alters the N antigen so that it is recognized as foreign. 
B)  Most renal patients express the phenotype M+N-S-s- where most potent forms of anti-N are found. 
C)  Treatment of renal patients depresses N-antigen expression. 
D)  None of the above 
A)  Formaldehyde alters the N antigen so that it is recognized as foreign. 
B)  Most renal patients express the phenotype M+N-S-s- where most potent forms of anti-N are found. 
C)  Treatment of renal patients depresses N-antigen expression. 
D)  None of the above

Question 18

Patients diagnosed with , where the autoantibody is directed against the K antigen, may exhibit a diminished expression of antigen.

Accepted Answer

A)  autoimmune hemolytic anemia 
B)  lupus erythematosus 
C)  rheumatoid arthritis 
D)  chronic granulomatous disease 
A)  autoimmune hemolytic anemia 
B)  lupus erythematosus 
C)  rheumatoid arthritis 
D)  chronic granulomatous disease

Question 19

You have a patient with Anti-P1. Theoretically, how many units would be compatible if you set up 10 units of blood?

Accepted Answer

A)  2 
B)  4 
C)  6 
D)  9 
A)  2 
B)  4 
C)  6 
D)  9

Question 20

Which organ removes cells coated with Jk antibodies from circulation?

Accepted Answer

A)  Spleen 
B)  Liver 
C)  Kidneys 
D)  Bone marrow 
A)  Spleen 
B)  Liver 
C)  Kidneys 
D)  Bone marrow

Exam 8: Blood Group Terminology and Common Blood Groups

What is the ISBT designation for the Lutheran blood group system?

What substances would be present in the saliva of a person with the LeLe HH SeSe AA genotype?

A patient who had a viral infection suspected to be Infectious mononucleosis may develop which antibody?

What sample requirement is essential for identification of a Kidd antibody?

Which antigen(s) is/are antithetical partner(s) to s?

All of the following are characteristics of Kidd antibodies except:

All of the following are characteristics of the Ena antigen except:

Lewis antibodies are of what immunoglobulin class?

Why is HDN not a consideration when the mother possesses anti-P1 in her serum?

What serologic factor distinguishes anti-Fy3 from anti-Fya or anti-Fyb?

What is the most common Kidd phenotype in the black population?

Why do En(a-) individuals have a reduced chance of infection with Plasmodium falciparum?

At what age does I antigen become detectable on infant cells?

What sequence of antigens coincides with strongest immunogen to weakest immunogen?

Anti-N is known to occur in patients undergoing dialysis with equipment sterilized by formaldehyde?

On which malaria receptor site is Duffy antigen dependent?

What is the etiology of dialysis-associated anti-N?

Patients diagnosed with , where the autoantibody is directed against the K antigen, may exhibit a diminished expression of antigen.

You have a patient with Anti-P1. Theoretically, how many units would be compatible if you set up 10 units of blood?

Which organ removes cells coated with Jk antibodies from circulation?

Red Blood Cells and Platelet Preservation: Historical Perspectives and Current Trends

Basic Genetics

Fundamentals of Immunology

Concepts in Molecular Biology

The Antiglobulin Test

The Abo Blood Group System

The Rh Blood Group System

Uncommon Blood Groups

Detection and Identification of Antibodies

Pre-Transfusion Testing

Blood Bank Technologies and Automation

Donor Selection

Transfusion-Transmitted Diseases

Component Preparation

Transfusion Therapy

Adverse Effects of Blood Transfusion

Apheresis

Cellular Therapy in the Transplant Setting

Hemolytic Disease of the Fetus and Newborn

Autoimmune Hemolytic Anemias

Tissue Banking As Part of the Transfusion Service

The Hla System

Relationship Testing

Quality Management

Patient Blood Management

Transfusion Safety and Federal Regulatory Requirements

Laboratory Information Systems in the Blood Bank

Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services

Filters

All of the following are characteristics of the En^a antigen except:

Why is HDN not a consideration when the mother possesses anti-P₁ in her serum?

What serologic factor distinguishes anti-Fy3 from anti-Fy^a or anti-Fy^b?