Exam 8: Blood Group Terminology and Common Blood Groups

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A woman undergoing a hysterectomy requires two units of blood. The antibody screen was negative. One unit was incompatible in the Coombs phase (2+), the other unit was compatible. Give a reason why this antibody was not detected in the antibody screen.

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When red blood cells are placed in a solution of 2M urea, the red blood cells will lyse. However, it has been shown that which red blood cells are resistant to lysis?

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Infection with which organism is associated with naturally occurring IgM anti-K.

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Why is dosage inconsistent in the Duffy blood group?

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What are the antibody characteristics of Fy3, Fy4, and Fy5?

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What abnormal blood cell morphology is associated with the McLeod phenotype?

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What characteristic differentiates Ss antigens from MN antigens?

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Which of the following statements about the Lewis system is not true?

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Alloanti-Lub will react with Lu(a+b+) cells than/as with Lu(a-b+) cells.

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Black persons who genotype as Fy4Fy4 will phenotype as:

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What type of hemolytic transfusion reaction (HTR) occurs more frequently in patients with Jk antibodies?

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How is the Luke (LKE) system related to the P blood group system?

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Anti-Jka was identified in a previously transfused patient. Five cells that were homozygous for Jka yielded 2+ reactions in the AHG phase. The same cells were treated with ficin and yielded 3+ reactions in AHG. Therefore, Jka is by enzyme treatment.

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A woman came in for a cesarean section. The antibody screen was positive with a 3+ reaction in the AHG phase using screening cell I. Screening cells II and III were negative in all phases. An 8-cell panel was performed that paralleled the antibody screen, where three cells reacted 3+ at AHG and five cells were negative at all phases of reactivity. The antibody identified was anti-Kell. What procedure might be helpful in predicting the infant's susceptibility to HDN?

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What Kidd antibody will react with all panel cells and phenotype as Jk(a-b-)?

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Where are Lewis antigens found?

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Approximately what percentage of the black population is [Le(a-b-)]?

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What Kell phenotype is found in highest frequency in the white population?

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Why is anti-LebL the antibody of choice when phenotyping red blood cells?

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What is the source of anti-M lectin?

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