Exam 8: Blood Group Terminology and Common Blood Groups

The M and N antigens exhibit dosage. Therefore, if a person inherits the homozygous genotype MM, their red blood cells will react with anti-M than/as those of a person with a heterozygous genotype of MN.

Most Kell autoantibodies are directed against which antigens that are usually undefined?

Red blood cells that phenotyped as [Le(a-b-)] are incubated with plasma containing Le^a substance. The red blood cells convert to the phenotype [Le(a+b-)]. Whereas the same red blood cells incubated with saliva containing Le^a substance do not convert. Why?

Why are the M and N antigens important for paternity testing?

What would be the probable genotype of a patient who phenotypes as ABLe (a-b-)?

What fatal disease is associated with the McLeod phenotype?

A blood bank technologist needed to confirm the presence of anti-P₁ in a patient specimen. Fresh cells were not available for use, so an old panel that contained cells positive for P₁ was used. No cells positive for the antigen reacted at any phase of the antiglobulin test, whereas cells from the screening cells showed specificity for the presence of anti-P₁. What is a possible explanation for this?

Anti-M will react strongest with which cells?

Most blood group alleles are:

All of the following are grouped with the para-Kell antigens except:

Name the substance used to neutralize antibodies to P1.

A patient who has a pathologic autoanti-I must be transfused with:

Anti-Fs is more likely to react with which cells?

Lutheran antibodies are rarely associated with causing hemolytic disease of the newborn (HDN) for which of the following reasons?

How is the En^a antigen related to the Wr(a-b-) phenotype?

Cord blood cells and adult cells that have the rare i phenotype will both demonstrate which reaction?

Autoantibodies to U antigen may be found in patients with:

What effect do enzyme-treated cells have on anti-I detection?

What antibody gives a 1+ reaction in undiluted and diluted samples?

What finding may protect individuals from making alloanti-Lu^b in dominant In(Lu) genotypes?