Question 1

The average life span of a circulating neutrophil is:

Accepted Answer

A)  6 to 10 hours 
B)  6 to 10 days 
C)  1 to 3 hours 
D)  1 to 3 days 
E)  24 hours 
A)  6 to 10 hours 
B)  6 to 10 days 
C)  1 to 3 hours 
D)  1 to 3 days 
E)  24 hours

Question 2

What bone marrow interpretation would be assessed to a complete count that showed neutrophilia with an increase in bone marrow cellularity, and increased myeloid-to-erythroid ratio?

Accepted Answer

A)  Granulocytic hypoplasia 
B)  Marrow hypoplasia 
C)  Granulocytic hyperplasia 
D)  Marrow hyperplasia 
E)  None of the above 
A)  Granulocytic hypoplasia 
B)  Marrow hypoplasia 
C)  Granulocytic hyperplasia 
D)  Marrow hyperplasia 
E)  None of the above

Question 3

The myeloid-to-erythroid ratio represents:

Accepted Answer

A)  The ratio of granulocytic and their precursors to nucleated erythrocytes and their precursors 
B)  The ratio of myeloid to non-nucleated erythroid cells 
C)  The ratio of myeloid to eosinophilic cells 
D)  The ratio of monocytoid to erythroid cells 
E)  None of the above 
A)  The ratio of granulocytic and their precursors to nucleated erythrocytes and their precursors 
B)  The ratio of myeloid to non-nucleated erythroid cells 
C)  The ratio of myeloid to eosinophilic cells 
D)  The ratio of monocytoid to erythroid cells 
E)  None of the above

Question 4

Marrow erythroblasts containing bright-blue iron specks when stained are called:

Accepted Answer

A)  Sideroblasts 
B)  Siderocytes 
C)  Histiocytes 
D)  Erythrocytes 
E)  None of the above 
A)  Sideroblasts 
B)  Siderocytes 
C)  Histiocytes 
D)  Erythrocytes 
E)  None of the above

Question 5

The EDTA chelation method is used for iron studies in bone biopsy. What purpose does it serve?

Accepted Answer

A)  Binds hemosiderin 
B)  Binds magnesium 
C)  Binds calcium 
D)  Binds ferritin 
E)  None of the above 
A)  Binds hemosiderin 
B)  Binds magnesium 
C)  Binds calcium 
D)  Binds ferritin 
E)  None of the above

Question 6

Which cells have the two unique biologic characteristics of self-renewal and multilineage differentiation?

Accepted Answer

A)  Pronormoblasts 
B)  Stem cells 
C)  Myeloblasts 
D)  Lymphoblast 
E)  Eosinophil 
A)  Pronormoblasts 
B)  Stem cells 
C)  Myeloblasts 
D)  Lymphoblast 
E)  Eosinophil

Question 7

The most appropriate site for a successful bone marrow aspiration in an adult patient would be:

Accepted Answer

A)  Calvariae 
B)  Scapula 
C)  Iliac crest 
D)  Long bones 
E)  None of the above 
A)  Calvariae 
B)  Scapula 
C)  Iliac crest 
D)  Long bones 
E)  None of the above

Question 8

The hematopoietic system consists of which of the following?

Accepted Answer

A)  Bone marrow 
B)  Lymph node 
C)  Spleen 
D)  Liver 
E)  All of the above 
A)  Bone marrow 
B)  Lymph node 
C)  Spleen 
D)  Liver 
E)  All of the above

Question 9

What is the site of erythropoietin production?

Accepted Answer

A)  Spleen 
B)  Kidney 
C)  Liver 
D)  Bone marrow 
E)  None of the above 
A)  Spleen 
B)  Kidney 
C)  Liver 
D)  Bone marrow 
E)  None of the above

Exam 2: Bone Marrow

The average life span of a circulating neutrophil is:

What bone marrow interpretation would be assessed to a complete count that showed neutrophilia with an increase in bone marrow cellularity, and increased myeloid-to-erythroid ratio?

The myeloid-to-erythroid ratio represents:

Marrow erythroblasts containing bright-blue iron specks when stained are called:

The EDTA chelation method is used for iron studies in bone biopsy. What purpose does it serve?

Which cells have the two unique biologic characteristics of self-renewal and multilineage differentiation?

The most appropriate site for a successful bone marrow aspiration in an adult patient would be:

The hematopoietic system consists of which of the following?

What is the site of erythropoietin production?

Morphology of Human Blood and Marrow Cells: Hematopoiesis

The Red Blood Cell: Structure and Function

Anemia: Diagnosis and Clinical Considerations

Evaluation of Red Blood Cell Morphology and Introduction to Platelet and White Blood Cell Morphology

Iron Metabolism and Hypochromic Anemias

Megaloblastic Anemias

Aplastic Anemia Including Pure Red Cell Aplasia and Congenital Dyserythropoietic Anemia and Paroxysmal Nocturnal Hemoglobinuria

Introduction to Hemolytic Anemias: Intracorpuscular Defects: I Hereditary Defects of the Red Cell Membrane

Hemolytic Anemias: Intracorpuscular Defects: II Hereditary Enzyme Deficiencies

Hemolytic Anemias: Intracorpuscular Defects: III the Hemoglobinopathies

Hemolytic Anemias: Intracorpuscular Defects: Iv Thalassemia

Hemolytic Anemias: Extracorpuscular Defects

Hypoproliferative Anemia: Anemia Associated With Systemic Diseases

Cell Biology, Disorders of Neutrophils, Infectious Mononucleosis, and Reactive Lymphocytosis

Introduction to Leukemia and the Acute Leukemias

Chronic Myeloproliferative Disorders I: Chronic Myelogenous Leukemia

Chronic Myeloproliferative Disorders Ii: Polycythemia Vera, Essential Thrombocythemia, and Idiopathic Myelofibrosis

Myelodysplastic Syndromes

Chronic Lymphocytic Leukemia and Related Lymphoproliferative Disorders

The Lymphomas

Multiple Myeloma and Related Plasma Cell Disorders

Lipid Lysosomal Storage Diseases and Histiocytosis

Introduction to Hemostasis

Disorders of Primary Hemostasis: Quantitative and Qualitative Platelet Disorders and Vascular Disorders

Disorders of Plasma Clotting Factors

Interaction of the Fibrinolytic, Coagulation, and Kinin Systems; Disseminated Intravascular Coagulation; and Related Pathology

Introduction to Thrombosis and Anticoagulant Therapy

Quality Control in the Hematology Laboratory

Body Fluid Examination: the Qualitative, Quantitative, and Morphologic Analysis of Serous, Cerebrospinal, and Synovial Fluids

Hematology Methods

Principles of Automated Differential Analysis

Coagulation Procedures

Applications of Flow Cytometry to Hematology and Hemostasis

Molecular Diagnostic Techniques in Hematopathology

Special Stainscytochemistry

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