Question 1

__________ acts as the stabilizer of the fibrin gel.

Accepted Answer

A)  Factor X 
B)  Factor XIII 
C)  Factor I 
D)  Factor VI 
E)  Factor VII 
A)  Factor X 
B)  Factor XIII 
C)  Factor I 
D)  Factor VI 
E)  Factor VII

Question 2

Which laboratory test is prolonged in a factor XII deficiency?

Accepted Answer

A)  TT 
B)  PT 
C)  APTT 
D)  All of the above 
E)  None of the above 
A)  TT 
B)  PT 
C)  APTT 
D)  All of the above 
E)  None of the above

Question 3

The bleeding time in von Willebrand's disease (vWD) will correct with infusion of _________.

Accepted Answer

A)  Normal platelets 
B)  Normal plasma 
C)  Plasma from person with vWD 
D)  All of the above 
E)  None of the above 
A)  Normal platelets 
B)  Normal plasma 
C)  Plasma from person with vWD 
D)  All of the above 
E)  None of the above

Question 4

All of the following statements are true regarding factor IX except:

Accepted Answer

A)  Factor IX is a vitamin K-dependent factor. 
B)  Factor IX is synthesized in the liver. 
C)  Factor IX is increased in hemophilia B. 
D)  Factor IX is present in serum but not in absorbed plasma. 
E)  Factor IX is decreased in liver disease. 
A)  Factor IX is a vitamin K-dependent factor. 
B)  Factor IX is synthesized in the liver. 
C)  Factor IX is increased in hemophilia B. 
D)  Factor IX is present in serum but not in absorbed plasma. 
E)  Factor IX is decreased in liver disease.

Question 5

Which is (are) an effective treatment(s) for vWD?

Accepted Answer

A)  Cryoprecipitate 
B)  Concentrates of vWF 
C)  Red blood cells 
D)  A and B 
E)  A and C 
A)  Cryoprecipitate 
B)  Concentrates of vWF 
C)  Red blood cells 
D)  A and B 
E)  A and C

Question 6

Which conditions or factors lead to a decrease in factor II?

Accepted Answer

A)  Liver dysfunction 
B)  Broad-spectrum antibiotic use 
C)  Coumarin therapy 
D)  Abnormal absorption of vitamin K in intestinal tract 
E)  All of the above 
A)  Liver dysfunction 
B)  Broad-spectrum antibiotic use 
C)  Coumarin therapy 
D)  Abnormal absorption of vitamin K in intestinal tract 
E)  All of the above

Question 7

What is the treatment of choice in the acquired dysprothrombinemias?

Accepted Answer

A)  Immunosuppressive drugs 
B)  Whole blood 
C)  Prothrombin complex concentrates 
D)  Hormonal therapy 
E)  None of the above 
A)  Immunosuppressive drugs 
B)  Whole blood 
C)  Prothrombin complex concentrates 
D)  Hormonal therapy 
E)  None of the above

Question 8

What is the normal range of fibrinogen in plasma?

Accepted Answer

A)  50-300 mg/dL 
B)  100-350 mg/dL 
C)  200-400 mg/dL 
D)  100-200 mg/dL 
E)  None of the above 
A)  50-300 mg/dL 
B)  100-350 mg/dL 
C)  200-400 mg/dL 
D)  100-200 mg/dL 
E)  None of the above

Exam 26: Disorders of Plasma Clotting Factors

__________ acts as the stabilizer of the fibrin gel.

Which laboratory test is prolonged in a factor XII deficiency?

The bleeding time in von Willebrand's disease (vWD) will correct with infusion of _________.

All of the following statements are true regarding factor IX except:

Which is (are) an effective treatment(s) for vWD?

Which conditions or factors lead to a decrease in factor II?

What is the treatment of choice in the acquired dysprothrombinemias?

What is the normal range of fibrinogen in plasma?

Morphology of Human Blood and Marrow Cells: Hematopoiesis

Bone Marrow

The Red Blood Cell: Structure and Function

Anemia: Diagnosis and Clinical Considerations

Evaluation of Red Blood Cell Morphology and Introduction to Platelet and White Blood Cell Morphology

Iron Metabolism and Hypochromic Anemias

Megaloblastic Anemias

Aplastic Anemia Including Pure Red Cell Aplasia and Congenital Dyserythropoietic Anemia and Paroxysmal Nocturnal Hemoglobinuria

Introduction to Hemolytic Anemias: Intracorpuscular Defects: I Hereditary Defects of the Red Cell Membrane

Hemolytic Anemias: Intracorpuscular Defects: II Hereditary Enzyme Deficiencies

Hemolytic Anemias: Intracorpuscular Defects: III the Hemoglobinopathies

Hemolytic Anemias: Intracorpuscular Defects: Iv Thalassemia

Hemolytic Anemias: Extracorpuscular Defects

Hypoproliferative Anemia: Anemia Associated With Systemic Diseases

Cell Biology, Disorders of Neutrophils, Infectious Mononucleosis, and Reactive Lymphocytosis

Introduction to Leukemia and the Acute Leukemias

Chronic Myeloproliferative Disorders I: Chronic Myelogenous Leukemia

Chronic Myeloproliferative Disorders Ii: Polycythemia Vera, Essential Thrombocythemia, and Idiopathic Myelofibrosis

Myelodysplastic Syndromes

Chronic Lymphocytic Leukemia and Related Lymphoproliferative Disorders

The Lymphomas

Multiple Myeloma and Related Plasma Cell Disorders

Lipid Lysosomal Storage Diseases and Histiocytosis

Introduction to Hemostasis

Disorders of Primary Hemostasis: Quantitative and Qualitative Platelet Disorders and Vascular Disorders

Interaction of the Fibrinolytic, Coagulation, and Kinin Systems; Disseminated Intravascular Coagulation; and Related Pathology

Introduction to Thrombosis and Anticoagulant Therapy

Quality Control in the Hematology Laboratory

Body Fluid Examination: the Qualitative, Quantitative, and Morphologic Analysis of Serous, Cerebrospinal, and Synovial Fluids

Hematology Methods

Principles of Automated Differential Analysis

Coagulation Procedures

Applications of Flow Cytometry to Hematology and Hemostasis

Molecular Diagnostic Techniques in Hematopathology

Special Stainscytochemistry

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