Question 1

Serologic tests determine a person's:

Accepted Answer

A)  genotype. 
B)  haplotype. 
C)  phenotype. 
D)  all of the above. 
A)  genotype. 
B)  haplotype. 
C)  phenotype. 
D)  all of the above.

Question 2

All of the following statements are representative of Lewis antibodies except:

Accepted Answer

A)  they occur frequently in pregnant women. 
B)  they occur more often in group O persons than A or B. 
C)  they are destroyed by enzymes. 
D)  they can be neutralized by Lewis substances. 
A)  they occur frequently in pregnant women. 
B)  they occur more often in group O persons than A or B. 
C)  they are destroyed by enzymes. 
D)  they can be neutralized by Lewis substances.

Question 3

What is the International Society of Blood Transfusion (ISBT) assignment for the antigen P²?

Accepted Answer

A)  003001 
B)  004001 
C)  003100 
D)  005001 
A)  003001 
B)  004001 
C)  003100 
D)  005001

Question 4

What is the ISBT designation for the Kidd blood group system?

Accepted Answer

A)  101 
B)  009 
C)  002 
D)  107 
A)  101 
B)  009 
C)  002 
D)  107

Question 5

What would be the probable genotype of a patient who phenotypes as ABLe (a-b-)?

Accepted Answer

A)  LeLe sese hh AB 
B)  lele sese Hh OO 
C)  lele sese HH AB 
D)  Lele Sese hh OO 
A)  LeLe sese hh AB 
B)  lele sese Hh OO 
C)  lele sese HH AB 
D)  Lele Sese hh OO

Question 6

A person who inherits alleles Fya and Fyb will carry which antigens on their red blood cells?

Accepted Answer

A)  Only Fya antigen 
B)  Only Fyb antigen 
C)  Both Fya and Fyb antigen 
D)  Neither Fya or Fyb antigen 
A)  Only Fya antigen 
B)  Only Fyb antigen 
C)  Both Fya and Fyb antigen 
D)  Neither Fya or Fyb antigen

Question 7

An individual from Bombay who has inherited the Le gene will have a phenotype of:

Accepted Answer

A)  Le(a-b-). 
B)  Le(a+b+). 
C)  Le(a+b-). 
D)  Le(a-b+). 
A)  Le(a-b-). 
B)  Le(a+b+). 
C)  Le(a+b-). 
D)  Le(a-b+).

Question 8

At what phase of the antihuman globulin test will anti-Kell be detected?

Accepted Answer

A)  IS 
B)  37°C 
C)  AHG 
D)  All of the above 
A)  IS 
B)  37°C 
C)  AHG 
D)  All of the above

Question 9

You have a patient with Anti-P1. Theoretically, how many units would be compatible if you set up 10 units of blood?

Accepted Answer

A)  2 
B)  4 
C)  6 
D)  9 
A)  2 
B)  4 
C)  6 
D)  9

Question 10

Alloanti-Lub will react_______________ with Lu(a+b+) cells than/as with Lu(a-b+) cells.

Accepted Answer

A)  stronger 
B)  weaker 
C)  the same 
D)  none of the above 
A)  stronger 
B)  weaker 
C)  the same 
D)  none of the above

Question 11

Where are the Duffy antigens found?

Accepted Answer

A)  Red blood cells 
B)  Platelets 
C)  Lymphocytes 
D)  All of the above 
A)  Red blood cells 
B)  Platelets 
C)  Lymphocytes 
D)  All of the above

Question 12

What effect do enzyme-treated cells have on anti-I detection?

Accepted Answer

A)  Enhances reactivity 
B)  Destroys reactivity 
C)  No effect 
D)  None of the above 
A)  Enhances reactivity 
B)  Destroys reactivity 
C)  No effect 
D)  None of the above

Question 13

Persons who express the phenotype P2 are at risk for developing anti-P1 when handling what animal species?

Accepted Answer

A)  Dogs 
B)  Cats 
C)  Pigeons 
D)  Mice 
A)  Dogs 
B)  Cats 
C)  Pigeons 
D)  Mice

Question 14

Persons who phenotype as Fy(a-b-) are resistant to infection by which organism?

Accepted Answer

A)  Plasmodium falciparum 
B)  Plasmodium vivax 
C)  Plasmodium ovale 
D)  Plasmodium malariae 
A)  Plasmodium falciparum 
B)  Plasmodium vivax 
C)  Plasmodium ovale 
D)  Plasmodium malariae

Question 15

What biochemical substituent is responsible for the i determinant?

Accepted Answer

A)  Two repeating N-acetyllactosamine units on H3 structures 
B)  Two repeating N-acetyllactosamine units on H4 structures 
C)  Two repeating N-acetyllactosamine units on H2 structures 
D)  Two repeating N-acetyllactosamine units on H1 structures 
A)  Two repeating N-acetyllactosamine units on H3 structures 
B)  Two repeating N-acetyllactosamine units on H4 structures 
C)  Two repeating N-acetyllactosamine units on H2 structures 
D)  Two repeating N-acetyllactosamine units on H1 structures

Question 16

A patient who has a pathologic autoanti-I must be transfused with:

Accepted Answer

A)  a leukocyte filter. 
B)  a cold pack. 
C)  a blood warmer 
D)  none of the above 
A)  a leukocyte filter. 
B)  a cold pack. 
C)  a blood warmer 
D)  none of the above

Question 17

The gene that codes for P1 is located on which chromosome?

Accepted Answer

A)  22 
B)  12 
C)  9 
D)  4 
A)  22 
B)  12 
C)  9 
D)  4

Question 18

Anti-Jka was identified in a previously transfused patient. Five cells that were homozygous for Jka yielded 2+ reactions in the AHG phase. The same cells were treated with ficin and yielded 3+ reactions in AHG. Therefore, Jka is _______________by enzyme treatment.

Accepted Answer

A)  destroyed 
B)  enhanced 
C)  unaffected 
D)  none of the above 
A)  destroyed 
B)  enhanced 
C)  unaffected 
D)  none of the above

Question 19

Antigens in the CH/RG blood group system are described as:

Accepted Answer

A)  resistant to ficin treatment. 
B)  antithetical partners. 
C)  well developed on cord cells. 
D)  adsorbed onto the red blood cell membrane. 
A)  resistant to ficin treatment. 
B)  antithetical partners. 
C)  well developed on cord cells. 
D)  adsorbed onto the red blood cell membrane.

Question 20

What percentage of the white population inherits the Le gene?

Accepted Answer

A)  50% 
B)  90% 
C)  10% 
D)  25% 
A)  50% 
B)  90% 
C)  10% 
D)  25%

Exam 8: Blood Group Terminology and the Other Blood Groups

Serologic tests determine a person's:

All of the following statements are representative of Lewis antibodies except:

What is the International Society of Blood Transfusion (ISBT) assignment for the antigen P²?

What is the ISBT designation for the Kidd blood group system?

What would be the probable genotype of a patient who phenotypes as ABLe (a-b-)?

A person who inherits alleles Fya and Fyb will carry which antigens on their red blood cells?

An individual from Bombay who has inherited the Le gene will have a phenotype of:

At what phase of the antihuman globulin test will anti-Kell be detected?

You have a patient with Anti-P1. Theoretically, how many units would be compatible if you set up 10 units of blood?

Alloanti-Lub will react_______________ with Lu(a+b+) cells than/as with Lu(a-b+) cells.

Where are the Duffy antigens found?

What effect do enzyme-treated cells have on anti-I detection?

Persons who express the phenotype P2 are at risk for developing anti-P1 when handling what animal species?

Persons who phenotype as Fy(a-b-) are resistant to infection by which organism?

What biochemical substituent is responsible for the i determinant?

A patient who has a pathologic autoanti-I must be transfused with:

The gene that codes for P1 is located on which chromosome?

Anti-Jka was identified in a previously transfused patient. Five cells that were homozygous for Jka yielded 2+ reactions in the AHG phase. The same cells were treated with ficin and yielded 3+ reactions in AHG. Therefore, Jka is _______________by enzyme treatment.

Antigens in the CH/RG blood group system are described as:

What percentage of the white population inherits the Le gene?

Red Blood Cells and Platelet Preservation: Historical Perspectives and Current Trends

Basic Genetics

Fundamentals of Immunology

Concepts in Molecular Biology

The Antiglobulin Test

The Abo Blood Group System

The RH Blood Group System

Detection and Identification of Antibodies

Pre-Transfusion Testing

Overview of the Routine Blood Bank Laboratory

Other Technologies and Automation

Donor Screening and Component Preparation

Apheresis

Transfusion Therapy

Cellular Therapy

Transfusion-Transmitted Diseases

Hemolytic Disease of the Fetus and Newborn

Autoimmune Hemolytic Anemias

The Hla System

Relationship Testing

Quality Management

Transfusion Safety and Federal Regulatory Requirements

Utilization Management

Laboratory Information Systems

Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services

Tissue Banking: A New Role for the Transfusion Service

Filters

A person who inherits alleles Fy^a and Fy^b will carry which antigens on their red blood cells?

Alloanti-Lu^b will react_______________ with Lu(a+b+) cells than/as with Lu(a-b+) cells.

Persons who express the phenotype P₂ are at risk for developing anti-P₁ when handling what animal species?

The gene that codes for P₁ is located on which chromosome?

Anti-Jk^a was identified in a previously transfused patient. Five cells that were homozygous for Jk^a yielded 2+ reactions in the AHG phase. The same cells were treated with ficin and yielded 3+ reactions in AHG. Therefore, Jk^a is _______________by enzyme treatment.