Question 1

What is unique about the Kpa antigen?

Accepted Answer

A)  It occurs in as high a frequency as its antithetical partner, Kpb. 
B)  It suppresses the expression of k and Jsb. 
C)  It enhances the expression of k and Jsb. 
D)  Its inheritance is most often a result of a consanguineous marriage. 
A)  It occurs in as high a frequency as its antithetical partner, Kpb. 
B)  It suppresses the expression of k and Jsb. 
C)  It enhances the expression of k and Jsb. 
D)  Its inheritance is most often a result of a consanguineous marriage.

Question 2

What red blood cell antigens do McLeod individuals express?

Accepted Answer

A)  TracekKpbJsbK11 
B)  KmKx 
C)  None 
D)  KkKpbJsa 
A)  TracekKpbJsbK11 
B)  KmKx 
C)  None 
D)  KkKpbJsa

Question 3

Which statement is true concerning the Cartwright antigens?

Accepted Answer

A)  The Ytb antigen is a strong immunogen. 
B)  Cord blood tests as Yta negative. 
C)  The Yta is inherited as a dominant allele. 
D)  Ytb is a high-frequency antigen. 
A)  The Ytb antigen is a strong immunogen. 
B)  Cord blood tests as Yta negative. 
C)  The Yta is inherited as a dominant allele. 
D)  Ytb is a high-frequency antigen.

Question 4

The Miltenberger subsystem is related to what major blood group system?

Accepted Answer

A)  Rh 
B)  Kell 
C)  P 
D)  MNSs 
A)  Rh 
B)  Kell 
C)  P 
D)  MNSs

Question 5

Where are Lewis antigens found?

Accepted Answer

A)  Plasma 
B)  Saliva 
C)  Milk 
D)  All of the above 
A)  Plasma 
B)  Saliva 
C)  Milk 
D)  All of the above

Question 6

Which enzyme is responsible for Lewis specificity?

Accepted Answer

A)  L-fucosyltransferase 
B)  N-acetylglycosyltransferase 
C)  D-galactosyltransferase 
D)  N-acetylgalactosyltransferase 
A)  L-fucosyltransferase 
B)  N-acetylglycosyltransferase 
C)  D-galactosyltransferase 
D)  N-acetylgalactosyltransferase

Question 7

What is found in secretions of Le(a-b-) individuals?

Accepted Answer

A)  Lea 
B)  Leb 
C)  Both a and b 
D)  None of the above 
A)  Lea 
B)  Leb 
C)  Both a and b 
D)  None of the above

Question 8

The Sc1 antigen occurs in approximately what percentage of the random population?

Accepted Answer

A)  100% 
B)  50% 
C)  10% 
D)  35% 
A)  100% 
B)  50% 
C)  10% 
D)  35%

Question 9

Both anti-Dia and anti-Dib are known to:

Accepted Answer

A)  cause severe HDN. 
B)  bind complement. 
C)  occur as a result of red blood cell stimulation. 
D)  react at the 37°C and IgG phases. 
A)  cause severe HDN. 
B)  bind complement. 
C)  occur as a result of red blood cell stimulation. 
D)  react at the 37°C and IgG phases.

Question 10

Why are P1 individuals susceptible to urinary tract infections by Escherichia coli?

Accepted Answer

A)  E. coli attach to antigen glycolipids on uroepithelial cells. 
B)  Polysaccharides from bacteria coat antigens on red blood cells. 
C)  P1 individuals have a decreased amount of immunoglobulins. 
D)  The fimbriae of E. coli have receptor sites for sialic acid. 
A)  E. coli attach to antigen glycolipids on uroepithelial cells. 
B)  Polysaccharides from bacteria coat antigens on red blood cells. 
C)  P1 individuals have a decreased amount of immunoglobulins. 
D)  The fimbriae of E. coli have receptor sites for sialic acid.

Question 11

Anti-M will react strongest with which cells?

Accepted Answer

A)  M+N- 
B)  M+N+ 
C)  M-N- 
D)  M-N+ 
A)  M+N- 
B)  M+N+ 
C)  M-N- 
D)  M-N+

Question 12

Why do En(a-) individuals have a reduced chance of infection with Plasmodium falciparum?

Accepted Answer

A)  There is a reduction in N-acetylneuraminic acid. 
B)  There is an increase in N-acetylneuraminic acid. 
C)  GPB is in an altered state. 
D)  There is a reduction in N-acetylgalactosamine. 
A)  There is a reduction in N-acetylneuraminic acid. 
B)  There is an increase in N-acetylneuraminic acid. 
C)  GPB is in an altered state. 
D)  There is a reduction in N-acetylgalactosamine.

Question 13

What can be done to rule in anti-M when only M+N+ red blood cells are available?

Accepted Answer

A)  Decrease the 37°C incubation time. 
B)  Use potentiating agents such as LISS. 
C)  Decrease the serum-to-cell ratio. 
D)  Use plasma anticoagulated in an acidic medium. 
A)  Decrease the 37°C incubation time. 
B)  Use potentiating agents such as LISS. 
C)  Decrease the serum-to-cell ratio. 
D)  Use plasma anticoagulated in an acidic medium.

Question 14

Disease associations have linked which Colton phenotype with monosomy-7?

Accepted Answer

A)  Co(a+b-) 
B)  Co(a+b+) 
C)  Co(a-b+) 
D)  Co(a-b-) 
A)  Co(a+b-) 
B)  Co(a+b+) 
C)  Co(a-b+) 
D)  Co(a-b-)

Question 15

Anti-i is found in association with what disease?

Accepted Answer

A)  Pneumonia 
B)  Infectious mononucleosis 
C)  Syphilis 
D)  Gonorrhea 
A)  Pneumonia 
B)  Infectious mononucleosis 
C)  Syphilis 
D)  Gonorrhea

Question 16

What name is attached to the Ena antigen?

Accepted Answer

A)  Envelope 
B)  Enterprise 
C)  Envision 
D)  Epitope 
A)  Envelope 
B)  Enterprise 
C)  Envision 
D)  Epitope

Question 17

How were Aua and Aub initially linked to the Lutheran system?

Accepted Answer

A)  Enhanced by enzymes (trysin) 
B)  Well-expressed on cord cells 
C)  Suppression by In(Lu) gene 
D)  Antigens active on H precursor substance 
A)  Enhanced by enzymes (trysin) 
B)  Well-expressed on cord cells 
C)  Suppression by In(Lu) gene 
D)  Antigens active on H precursor substance

Question 18

Where are the Kidd antigens found?

Accepted Answer

A)  Red blood cells 
B)  Platelets 
C)  Lymphocytes 
D)  Monocytes 
A)  Red blood cells 
B)  Platelets 
C)  Lymphocytes 
D)  Monocytes

Question 19

Which antigen is expressed on C4B complement fragments?

Accepted Answer

A)  Cha 
B)  Kna 
C)  Yka 
D)  Gya 
A)  Cha 
B)  Kna 
C)  Yka 
D)  Gya

Question 20

Approximately what percentage of the black population are s-?

Accepted Answer

A)  70% 
B)  98% 
C)  3% 
D)  25% 
A)  70% 
B)  98% 
C)  3% 
D)  25%

Exam 8: Blood Group Terminology and the Other Blood Groups

What is unique about the Kpa antigen?

What red blood cell antigens do McLeod individuals express?

Which statement is true concerning the Cartwright antigens?

The Miltenberger subsystem is related to what major blood group system?

Where are Lewis antigens found?

Which enzyme is responsible for Lewis specificity?

What is found in secretions of Le(a-b-) individuals?

The Sc1 antigen occurs in approximately what percentage of the random population?

Both anti-Dia and anti-Dib are known to:

Why are P1 individuals susceptible to urinary tract infections by Escherichia coli?

Anti-M will react strongest with which cells?

Why do En(a-) individuals have a reduced chance of infection with Plasmodium falciparum?

What can be done to rule in anti-M when only M+N+ red blood cells are available?

Disease associations have linked which Colton phenotype with monosomy-7?

Anti-i is found in association with what disease?

What name is attached to the Ena antigen?

How were Aua and Aub initially linked to the Lutheran system?

Where are the Kidd antigens found?

Which antigen is expressed on C4B complement fragments?

Approximately what percentage of the black population are s-?

Red Blood Cells and Platelet Preservation: Historical Perspectives and Current Trends

Basic Genetics

Fundamentals of Immunology

Concepts in Molecular Biology

The Antiglobulin Test

The Abo Blood Group System

The RH Blood Group System

Detection and Identification of Antibodies

Pre-Transfusion Testing

Overview of the Routine Blood Bank Laboratory

Other Technologies and Automation

Donor Screening and Component Preparation

Apheresis

Transfusion Therapy

Cellular Therapy

Transfusion-Transmitted Diseases

Hemolytic Disease of the Fetus and Newborn

Autoimmune Hemolytic Anemias

The Hla System

Relationship Testing

Quality Management

Transfusion Safety and Federal Regulatory Requirements

Utilization Management

Laboratory Information Systems

Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services

Tissue Banking: A New Role for the Transfusion Service

Filters

What is unique about the Kp^a antigen?

Both anti-Di^a and anti-Di^b are known to:

Why are P₁ individuals susceptible to urinary tract infections by Escherichia coli?

What name is attached to the En^a antigen?

How were Au^a and Au^b initially linked to the Lutheran system?

Which antigen is expressed on C₄B complement fragments?