Question 1

Cryoprecipitate is not used to treat which condition?

Accepted Answer

A)  Hemophilia A 
B)  von Willebrand's disease 
C)  Hemophilia B 
D)  Hypofibrinogenemia 
A)  Hemophilia A 
B)  von Willebrand's disease 
C)  Hemophilia B 
D)  Hypofibrinogenemia C

Question 2

Which of the following represents the final clerical check of a transfusion?

Accepted Answer

A)  The phlebotomist asks the patient to state his name and Social Security number and compares that information with the patient requisition. 
B)  The medical technologist compares the specimen label with computer information. 
C)  The nurse uses the patient's armband to compare patient identification with the patient crossmatch report and tags attached to the unit. 
D)  Two individuals verify affixing of proper labels to selected blood products. 
A)  The phlebotomist asks the patient to state his name and Social Security number and compares that information with the patient requisition. 
B)  The medical technologist compares the specimen label with computer information. 
C)  The nurse uses the patient's armband to compare patient identification with the patient crossmatch report and tags attached to the unit. 
D)  Two individuals verify affixing of proper labels to selected blood products. C

Question 3

Which of the following is not an indication for fresh frozen plasma (FFP) transfusion?

Accepted Answer

A)  Disseminated intravascular coagulation (DI
C)  
B)  Vitamin K deficiency 
C)  Factor VIII deficiency 
D)  Massive transfusion 
A)  Disseminated intravascular coagulation (DI
C)  
B)  Vitamin K deficiency 
C)  Factor VIII deficiency 
D)  Massive transfusion C

Question 4

Which class of vWD provides the least amount of vWF?

Accepted Answer

A)  Type I 
B)  Type IIB 
C)  Type III 
D)  Type IIA 
A)  Type I 
B)  Type IIB 
C)  Type III 
D)  Type IIA

Question 5

Which of the following are not at risk for developing cytomegalovirus (CMV) via CMV-positive blood products?

Accepted Answer

A)  CMV-positive heart transplant recipients 
B)  CMV-negative pregnant women 
C)  CMV-negative bone marrow transplant recipients 
D)  CMV-negative premature infants 
A)  CMV-positive heart transplant recipients 
B)  CMV-negative pregnant women 
C)  CMV-negative bone marrow transplant recipients 
D)  CMV-negative premature infants

Question 6

What component is indicated for patients who have had moderate to severe allergic transfusion reactions and have anti-IgA antibodies because of IgA deficiency?

Accepted Answer

A)  Whole blood 
B)  Packed RBCs 
C)  Washed RBCs 
D)  Granulocyte preparations 
A)  Whole blood 
B)  Packed RBCs 
C)  Washed RBCs 
D)  Granulocyte preparations

Question 7

Why is the increase in hemoglobin and hematocrit evident more quickly in red blood cell transfusions than in whole blood transfusions?

Accepted Answer

A)  Blood volume adjustment is less when red blood cells are transfused. 
B)  Blood volume adjustment is greater when red blood cells are transfused. 
C)  Whole blood takes longer to mix. 
D)  Whole blood is usually transfused through a porous filter. 
A)  Blood volume adjustment is less when red blood cells are transfused. 
B)  Blood volume adjustment is greater when red blood cells are transfused. 
C)  Whole blood takes longer to mix. 
D)  Whole blood is usually transfused through a porous filter.

Question 8

How is the whole blood that is collected from a donor different from whole blood circulating in someone's blood vessels?

Accepted Answer

A)  The anticoagulant in donor blood prevents activation of the coagulation system. 
B)  The citrate mixed with donor blood serves as substrate for red blood cell metabolism. 
C)  The pH of whole blood is higher in collected units than in blood vessels. 
D)  Immunogenicity is diminished in collected units. 
A)  The anticoagulant in donor blood prevents activation of the coagulation system. 
B)  The citrate mixed with donor blood serves as substrate for red blood cell metabolism. 
C)  The pH of whole blood is higher in collected units than in blood vessels. 
D)  Immunogenicity is diminished in collected units.

Question 9

How is cryoprecipitated AHF used with prosthetic vascular grafts?

Accepted Answer

A)  Bovine thrombin activates factor XIII, which acts as a fibrin solvent to prime grafts. 
B)  Bovine thrombin activates factor VIII, which acts as a fibrin glue to seal gaps. 
C)  Bovine thrombin activates fibrinogen, which acts as a fibrin glue to seal gaps. 
D)  None of the above 
A)  Bovine thrombin activates factor XIII, which acts as a fibrin solvent to prime grafts. 
B)  Bovine thrombin activates factor VIII, which acts as a fibrin glue to seal gaps. 
C)  Bovine thrombin activates fibrinogen, which acts as a fibrin glue to seal gaps. 
D)  None of the above

Question 10

In anemia uncomplicated by low plasma proteins or shock, the transfusion of:

Accepted Answer

A)  whole blood is most desirable. 
B)  plasma is desirable. 
C)  packed red blood cells is most desirable. 
D)  fresh frozen plasma is most desirable. 
A)  whole blood is most desirable. 
B)  plasma is desirable. 
C)  packed red blood cells is most desirable. 
D)  fresh frozen plasma is most desirable.

Question 11

What whole blood component contained in pheresed granulocyte concentrate warrants crossmatching of this product?

Accepted Answer

A)  White blood cells 
B)  Red blood cells 
C)  Platelets 
D)  Plasma 
A)  White blood cells 
B)  Red blood cells 
C)  Platelets 
D)  Plasma

Question 12

Platelets prepared from_____  are referred to as random donor platelets.

Accepted Answer

A)  recovered plasma 
B)  pheresis products 
C)  whole blood units 
D)  red blood cells 
A)  recovered plasma 
B)  pheresis products 
C)  whole blood units 
D)  red blood cells

Question 13

What is the recommended treatment for mild von Willebrand's disease?

Accepted Answer

A)  VIII concentrate 
B)  Fresh frozen plasma 
C)  Cryoprecipitate 
D)  DDAVP (1-Deamino-8-arginine vasopressin) 
A)  VIII concentrate 
B)  Fresh frozen plasma 
C)  Cryoprecipitate 
D)  DDAVP (1-Deamino-8-arginine vasopressin)

Question 14

In what disease state is acquired antithrombin III deficiency manifested?

Accepted Answer

A)  DIC 
B)  von Willebrand's disease 
C)  Liver disease 
D)  Lupus erythematosus 
A)  DIC 
B)  von Willebrand's disease 
C)  Liver disease 
D)  Lupus erythematosus

Question 15

Four units of packed RBCs were used in the operating room at 3 p.m. Can the remaining 2 units be returned to the blood bank at 5 p.m.?

Accepted Answer

A)  Yes, if the 2 units have been kept under the proper storage conditions 
B)  Yes, but only if the units are to be used for the same patient 
C)  No, units may have been out of blood bank for more than 4 hours 
D)  No, units have been out of the blood bank for longer than 30 minutes 
A)  Yes, if the 2 units have been kept under the proper storage conditions 
B)  Yes, but only if the units are to be used for the same patient 
C)  No, units may have been out of blood bank for more than 4 hours 
D)  No, units have been out of the blood bank for longer than 30 minutes

Question 16

What is the only blood component that provides high concentrations of vWF?

Accepted Answer

A)  FFP 
B)  Whole blood 
C)  Platelets 
D)  Cryoprecipitated AHF 
A)  FFP 
B)  Whole blood 
C)  Platelets 
D)  Cryoprecipitated AHF

Question 17

Cryoprecipitate AHF contains how much fibrinogen?

Accepted Answer

A)  500 to 750 mg 
B)  50 to 100 mg 
C)  150 to 250 mg 
D)  250 to 400 mg 
A)  500 to 750 mg 
B)  50 to 100 mg 
C)  150 to 250 mg 
D)  250 to 400 mg

Question 18

Which intravenous solution is not recommended for dilution of blood components because of red blood cell damage?

Accepted Answer

A)  0.9% saline 
B)  Dextrose 
C)  5% albumin 
D)  Plasma 
A)  0.9% saline 
B)  Dextrose 
C)  5% albumin 
D)  Plasma

Question 19

What plasma product is used to replace fluid in patients undergoing plasmapheresis procedures?

Accepted Answer

A)  Albumin 
B)  Plasma protein fraction 
C)  Immune globulin 
D)  Cryoprecipitate 
A)  Albumin 
B)  Plasma protein fraction 
C)  Immune globulin 
D)  Cryoprecipitate

Question 20

Cryoprecipitated AHF can be used in the treatment of:

Accepted Answer

A)  Bernard-Soulier syndrome. 
B)  von Willebrand's disease (vW
D) . 
C)  antithrombin III deficiency. 
D)  hemolytic uremic syndrome. 
A)  Bernard-Soulier syndrome. 
B)  von Willebrand's disease (vW
D) . 
C)  antithrombin III deficiency. 
D)  hemolytic uremic syndrome.

Exam 15: Transfusion Therapy

Cryoprecipitate is not used to treat which condition?

Which of the following represents the final clerical check of a transfusion?

Which of the following is not an indication for fresh frozen plasma (FFP) transfusion?

Which class of vWD provides the least amount of vWF?

Which of the following are not at risk for developing cytomegalovirus (CMV) via CMV-positive blood products?

What component is indicated for patients who have had moderate to severe allergic transfusion reactions and have anti-IgA antibodies because of IgA deficiency?

Why is the increase in hemoglobin and hematocrit evident more quickly in red blood cell transfusions than in whole blood transfusions?

How is the whole blood that is collected from a donor different from whole blood circulating in someone's blood vessels?

How is cryoprecipitated AHF used with prosthetic vascular grafts?

In anemia uncomplicated by low plasma proteins or shock, the transfusion of:

What whole blood component contained in pheresed granulocyte concentrate warrants crossmatching of this product?

Platelets prepared from_____ are referred to as random donor platelets.

What is the recommended treatment for mild von Willebrand's disease?

In what disease state is acquired antithrombin III deficiency manifested?

Four units of packed RBCs were used in the operating room at 3 p.m. Can the remaining 2 units be returned to the blood bank at 5 p.m.?

What is the only blood component that provides high concentrations of vWF?

Cryoprecipitate AHF contains how much fibrinogen?

Which intravenous solution is not recommended for dilution of blood components because of red blood cell damage?

What plasma product is used to replace fluid in patients undergoing plasmapheresis procedures?

Cryoprecipitated AHF can be used in the treatment of:

Red Blood Cells and Platelet Preservation: Historical Perspectives and Current Trends

Basic Genetics

Fundamentals of Immunology

Concepts in Molecular Biology

The Antiglobulin Test

The Abo Blood Group System

The RH Blood Group System

Blood Group Terminology and the Other Blood Groups

Detection and Identification of Antibodies

Pre-Transfusion Testing

Overview of the Routine Blood Bank Laboratory

Other Technologies and Automation

Donor Screening and Component Preparation

Apheresis

Cellular Therapy

Transfusion-Transmitted Diseases

Hemolytic Disease of the Fetus and Newborn

Autoimmune Hemolytic Anemias

The Hla System

Relationship Testing

Quality Management

Transfusion Safety and Federal Regulatory Requirements

Utilization Management

Laboratory Information Systems

Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services

Tissue Banking: A New Role for the Transfusion Service

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