Question 1

Each cryoprecipitate unit contains at least how much factor VIII?

Accepted Answer

A)  80 units 
B)  50 units 
C)  30 units 
D)  100 units 
A)  80 units 
B)  50 units 
C)  30 units 
D)  100 units

Question 2

The rejection of the transplantation of platelets from one individual to another is termed or defined as:

Accepted Answer

A)  a hemolytic transfusion reaction. 
B)  platelet refractoriness. 
C)  graft versus host disease. 
D)  none of the above. 
A)  a hemolytic transfusion reaction. 
B)  platelet refractoriness. 
C)  graft versus host disease. 
D)  none of the above.

Question 3

Which plateletpheresis product should be irradiated?

Accepted Answer

A)  Autologous unit collected prior to surgery 
B)  Random stock unit going to a patient with disseminated intravascular coagulation (DI
C)  
C)  A directed donation given by a mother to her son 
D)  A directed donation given by an unrelated family friend 
A)  Autologous unit collected prior to surgery 
B)  Random stock unit going to a patient with disseminated intravascular coagulation (DI
C)  
C)  A directed donation given by a mother to her son 
D)  A directed donation given by an unrelated family friend

Question 4

A patient with severe hemolytic anemia had a pulse of 120 beats per minute and a respiratory rate of 37 breaths per minute. What blood component is indicated for this patient?

Accepted Answer

A)  Plasma 
B)  Whole blood 
C)  Red blood cells 
D)  Platelets 
A)  Plasma 
B)  Whole blood 
C)  Red blood cells 
D)  Platelets

Question 5

Why is it recommended that factor VIII concentrates be used in patients with von Willebrand's disease?

Accepted Answer

A)  Because of the variability in vWF content. 
B)  Because of factor VIII's short half-life. 
C)  Factor VIII concentrates are reserved for hemophiliacs. 
D)  All of the above. 
A)  Because of the variability in vWF content. 
B)  Because of factor VIII's short half-life. 
C)  Factor VIII concentrates are reserved for hemophiliacs. 
D)  All of the above.

Question 6

What is the most efficient way to remove leukocytes from red blood cell units?

Accepted Answer

A)  Leukoreduction filters 
B)  Centrifugation 
C)  Deglycerolizing 
D)  Washing 
A)  Leukoreduction filters 
B)  Centrifugation 
C)  Deglycerolizing 
D)  Washing

Question 7

What is the purpose of dialysis in uremic patients?

Accepted Answer

A)  Release of functional von Willebrand factor (vWF) from endothelial cells 
B)  Removal of by-products of protein metabolism that renders vWF and platelets nonfunctional 
C)  Release of platelets from the bone marrow 
D)  All of the above 
A)  Release of functional von Willebrand factor (vWF) from endothelial cells 
B)  Removal of by-products of protein metabolism that renders vWF and platelets nonfunctional 
C)  Release of platelets from the bone marrow 
D)  All of the above

Question 8

A patient with paroxysmal cold hemoglobinuria (PCH) would require _____ in the event of a blood transfusion.

Accepted Answer

A)  irradiation 
B)  cytomegalovirus-negative units 
C)  a blood warmer 
D)  Hgb S-negative units 
A)  irradiation 
B)  cytomegalovirus-negative units 
C)  a blood warmer 
D)  Hgb S-negative units

Question 9

Which of the following statements concerning red blood cells prepared with additive solution 1 (AS-1) is true?

Accepted Answer

A)  The shelf-life is 35 days. 
B)  The AS-1 unit contains more plasma than the CPDA-1 red blood cells. 
C)  Red blood cell mass is lower than that of CPDA-1 red blood cells. 
D)  The hematocrit is lower than CPDA-1 red blood cells. 
A)  The shelf-life is 35 days. 
B)  The AS-1 unit contains more plasma than the CPDA-1 red blood cells. 
C)  Red blood cell mass is lower than that of CPDA-1 red blood cells. 
D)  The hematocrit is lower than CPDA-1 red blood cells.

Question 10

How would the hematocrit of a patient with chronic anemia be affected by transfusion of 2 units of whole blood versus transfusion with 3 units of packed RBCs?

Accepted Answer

A)  Patient's hematocrit would be equally affected. 
B)  The packed RBCs would increase the hematocrit more than the whole blood. 
C)  The whole blood would increase the hematocrit more than the packed RBCs. 
D)  The hematocrit would not change at all with the whole blood because of the plasma in the unit. 
A)  Patient's hematocrit would be equally affected. 
B)  The packed RBCs would increase the hematocrit more than the whole blood. 
C)  The whole blood would increase the hematocrit more than the packed RBCs. 
D)  The hematocrit would not change at all with the whole blood because of the plasma in the unit.

Question 11

What is the expiration on washed red blood cells?

Accepted Answer

A)  35 days 
B)  24 hours 
C)  42 days 
D)  6 hours 
A)  35 days 
B)  24 hours 
C)  42 days 
D)  6 hours

Question 12

Which of the following is not a function of the hospital transfusion committee?

Accepted Answer

A)  FDA certification 
B)  Reviewing transfusion reactions 
C)  Submitting reports of committee recommendations to medical staff 
D)  Ensuring proper procedures are upheld by hospital personnel 
A)  FDA certification 
B)  Reviewing transfusion reactions 
C)  Submitting reports of committee recommendations to medical staff 
D)  Ensuring proper procedures are upheld by hospital personnel

Question 13

Why is whole blood contraindicated for patients with severe chronic anemia?

Accepted Answer

A)  These patients have a reduced number of red blood cells. 
B)  The plasma volume of these patients is decreased. 
C)  The plasma volume of these patients is increased. 
D)  These patients have an increased number of red blood cells. 
A)  These patients have a reduced number of red blood cells. 
B)  The plasma volume of these patients is decreased. 
C)  The plasma volume of these patients is increased. 
D)  These patients have an increased number of red blood cells.

Question 14

Which of the following may be a serious manifestation of FFP transfusion in congenital factor deficiencies?

Accepted Answer

A)  Tachycardia 
B)  Pleurisy 
C)  Hypogammaglobulinemia 
D)  Pulmonary edema 
A)  Tachycardia 
B)  Pleurisy 
C)  Hypogammaglobulinemia 
D)  Pulmonary edema

Question 15

Factor IX concentrates contain which factors (otherwise known as "prothrombin complex")?

Accepted Answer

A)  I, V, VII, IX 
B)  II, V, VII, IX 
C)  II, VII, IX, X 
D)  V, VII, IX, XII 
A)  I, V, VII, IX 
B)  II, V, VII, IX 
C)  II, VII, IX, X 
D)  V, VII, IX, XII

Question 16

Bleeding disorders may be caused by:

Accepted Answer

A)  dysfunction of lymphocytes. 
B)  dysfunction of neutrophils. 
C)  dysfunction of platelets. 
D)  dysfunction of erythrocytes. 
A)  dysfunction of lymphocytes. 
B)  dysfunction of neutrophils. 
C)  dysfunction of platelets. 
D)  dysfunction of erythrocytes.

Question 17

What transfusion therapy is indicated for a patient who is found to be refractory to random platelets?

Accepted Answer

A)  Irradiated random donor platelets 
B)  Random platelets from other donors 
C)  Apheresis platelets from an HLA-compatible donor 
D)  Neutralization of antiplatelet antibodies by type-specific platelets 
A)  Irradiated random donor platelets 
B)  Random platelets from other donors 
C)  Apheresis platelets from an HLA-compatible donor 
D)  Neutralization of antiplatelet antibodies by type-specific platelets

Exam 15: Transfusion Therapy

Each cryoprecipitate unit contains at least how much factor VIII?

The rejection of the transplantation of platelets from one individual to another is termed or defined as:

Which plateletpheresis product should be irradiated?

A patient with severe hemolytic anemia had a pulse of 120 beats per minute and a respiratory rate of 37 breaths per minute. What blood component is indicated for this patient?

Why is it recommended that factor VIII concentrates be used in patients with von Willebrand's disease?

What is the most efficient way to remove leukocytes from red blood cell units?

What is the purpose of dialysis in uremic patients?

A patient with paroxysmal cold hemoglobinuria (PCH) would require _____ in the event of a blood transfusion.

Which of the following statements concerning red blood cells prepared with additive solution 1 (AS-1) is true?

How would the hematocrit of a patient with chronic anemia be affected by transfusion of 2 units of whole blood versus transfusion with 3 units of packed RBCs?

What is the expiration on washed red blood cells?

Which of the following is not a function of the hospital transfusion committee?

Why is whole blood contraindicated for patients with severe chronic anemia?

Which of the following may be a serious manifestation of FFP transfusion in congenital factor deficiencies?

Factor IX concentrates contain which factors (otherwise known as "prothrombin complex")?

Bleeding disorders may be caused by:

What transfusion therapy is indicated for a patient who is found to be refractory to random platelets?

Red Blood Cells and Platelet Preservation: Historical Perspectives and Current Trends

Basic Genetics

Fundamentals of Immunology

Concepts in Molecular Biology

The Antiglobulin Test

The Abo Blood Group System

The RH Blood Group System

Blood Group Terminology and the Other Blood Groups

Detection and Identification of Antibodies

Pre-Transfusion Testing

Overview of the Routine Blood Bank Laboratory

Other Technologies and Automation

Donor Screening and Component Preparation

Apheresis

Cellular Therapy

Transfusion-Transmitted Diseases

Hemolytic Disease of the Fetus and Newborn

Autoimmune Hemolytic Anemias

The Hla System

Relationship Testing

Quality Management

Transfusion Safety and Federal Regulatory Requirements

Utilization Management

Laboratory Information Systems

Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services

Tissue Banking: A New Role for the Transfusion Service

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